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고려대학교 교수소개

Knowledge & Innovation

생명과학대학

Home > 생명과학대학 >생명공학부

소개

Prof. 이호정

Tel: 02-3290-3006 (Lab: 3466)

Fax: 3290-3508

E-mail: lhojoung@korea.ac.kr

  • About Professor
  • Curriculum vitae
  • Publication
  • Research
  • Teaching
  • Lab Members
  • Profile

    연구분야 : 식물분자생물학
    위치 : 생명과학관 서관 509호 (Lab: L512) Education

  • Curriculum

    Education 
     
     BS 1987-1991 Pusan National University 
     MS 1991-1993 Pohang University (POSTECH) 
     Ph.D. 1997-2002 The University of Arizona
     
     
    Professional Experiences 
     
     2008. 9 - Present Associate professor, Div. Biotechnology, Korea University 
     2003. 9 - 2008. 8 Assistant professor, Div. Biotechnology, Korea University 
     2002. 8 - 2003. 8 Post-Doctor, KLESL, Kwangiu, Korea 

     

  • Publication

    2016
     

    MYBD employed by HY5 increases anthocyanin accumulation via repression of MYBL2 in Arabidopsis. The Plant Journal84(6), 1192-1205.

     

    Nguyen, N. H., & Lee, H. (2016). MYB-related transcription factors function as regulators of the circadian clock and anthocyanin biosynthesis in Arabidopsis. Plant signaling & behavior, 11(3), e1139278.

     

    Nguyen, N. H., Kim, J. H., Kwon, J., Jeong, C. Y., Lee, W., Lee, D., ... & Lee, H. (2016). Characterization of Arabidopsis thaliana FLAVONOL SYNTHASE 1 (FLS1)-overexpression plants in response to abiotic stress. Plant Physiology and Biochemistry, 103, 133-142.

     

    Lee, W. J., Jeong, C. Y., Kwon, J., Van Kien, V., Lee, D., Hong, S. W., & Lee, H. (2016). Drastic anthocyanin increase in response to PAP1 overexpression in fls1 knockout mutant confers enhanced osmotic stress tolerance in Arabidopsis thaliana. Plant cell reports, 35(11), 2369-2379.

     

    Nguyen, N. H., Jeong, C. Y., Lee, W. J., & Lee, H. (2016). Identification of a novel Arabidopsis mutant showing sensitivity to histone deacetylase inhibitors. Applied Biological Chemistry, 59(6), 855-860.

     
     
     
    2015
     
     Tien Thanh Vu, Chan Young Jeong, Hoai Nguyen Nguyen, Dongho Lee, Sang A Lee, Ji Hye Kim, Suk-Whan Hong and Hojoung Lee (2015) Characterization of Brassica napus Flavonol Synthase Involved in Flavonol Biosynthesis in Brassica napus L.. J Agric Food Chem. 63:7819-7829.
     
     Nguyen Hoai Nguyen, Chan Young Jeong, Geun-Ho Kang, Sang-Dong Yoo, Suk-Whan Hong and Hojoung Lee (2015) MYBD employed by HY5 increases anthocyanin accumulation via repression of MYBL2 in Arabidopsis . Plant Journal (in press) 
     
     
     
     
    2014 
     
           
     
    Jun Hyeok Kim, Woo Young Hyun, Hoai Nguyen Nguyen, Chan Young Jeong, Liming Xiong, Suk-Whan Hong and Hojoung Lee (2014) AtMyb7, a subgroup 4 R2R3 Myb, negatively regulates ABA-induced inhibition of seed germination by blocking the expression of the bZIP transcription factor ABI5. Plant Cell Environ. 38: 559-571.
     
     Ji Hae Lee, Jung Eun Lee, Yeojin Kim, Hojoung Lee , Hee-jin Jun, and Sung-Joon Lee (2014) Multidrug and Toxic Compound Extrusion Protein-1 (MATE1/SLC47A1) Is a Novel Flavonoid Transporter. J Agric Food Chem. 62: 9690-9698.
     
    2013 
     
     
    Nguyen Hoai Nguyen, Jun Hyeok Kim, Woo Young Hyun, Ngoc Trinh Nguyen, Suk-Whan Hong, Hojoung Lee (2013) TTG1 mediated flavonols biosynthesis alleviates root growth inhibition in response to ABA. Plant Cell Rep. 32:503-514.
     
     Jun Hyeok Kim, Nguyen Hoai Nguyen, Chan Young Jeong, Ngoc Trinh Nguyen, Suk-Whan Hong and Hojoung Lee (2013) Loss of the R2R3 MYB, AtMyb73, causes up-regulation of the expression of the SOS1 and SOS3 genes in response to high salinity in Arabidopsis. Journal of Plant Physiology. 170: 1461-1465.
     
     Nguyen Hoai Nguyen, Jun Hyeok Kim, Suk-Whan Hong and Hojoung Lee (2013) Inhibition of histone deacetylation alters Arabidopsis root growth in response to auxin via PIN1 degradation. Plant Cell Rep. 32: 1625-1636.
     
     Yerim Kwon, Jun Hyeok Kim, Hoai Nguyen Nguyen, Yusuke Jikumaru, Yuji Kamiya, Suk-Whan Hong, and Hojoung Lee (2013) A Novel Arabidopsis MYB-like Transcription Factor MYBH Regulates Hypocotyl Elongation by Enhancing Auxin Accumulation. Journal of Experimental Botany. 64: 3911-3922.
     
     Jun Hyeok Kim, Hoai Nguyen Nguyen, Ngoc Trinh Nguyen, Suk-Whan Hong and Hojoung Lee (2013) Loss of all three calreticulins, CRT1, CRT2 and CRT3, causes enhanced sensitivity to water stress in Arabidopsis. Plant Cell Rep. 32: 1843-1853.
     
     
    2012 
     
     
    Sooah Kim, Eun Ju Yun, Md. Aktar Hossain, Hojoung Lee , Kyoung Heon Kim (2012) Global profiling of ultraviolet-induced metabolic disruption in Melissa officinalis by using gas chromatography-mass spectrometry. Analytical and Bioanalytical Chemistry. 404: 553-562.
     
     
     
     
    Jee Eun Oh, Young Hye Kim, Jun Hyeok Kim, Ye Rim Kwon and Hojoung Lee (2011) Enhanced level of anthocyanin leads to increased salt tolerance in Arabidopsis PAP1-D plants upon sucrose treatment. (SCIE) The Korean Society for Applied Biological Chemistry. 54: 79-88.
     
     
    2011 
     
     
    Jee Eun Oh, Ye Rim Kwon, Jun Hyeok Kim, Hana Noh, Suk-Whan Hong and Hojoung Lee (2011) A dual role for Myb60 in stomatal regulation and root growth of Arabidopsis thaliana under drought stress. Plant Molecular Biology. 77: 91-103.
     
     
     Jee Eun Oh, Young Hye Kim, Jun Hyeok Kim, Ye Rim Kwon and Hojoung Lee (2011) Enhanced level of anthocyanin leads to increased salt tolerance in Arabidopsis PAP1-D plants upon sucrose treatment. (SCIE) The Korean Society for Applied Biological Chemistry. 54: 79-88.
     
     
    2010
     
     Seung Hee Chu, Hana-Noh, Sooah Kim, Kyoung Heon Kim, Suk-Whan Hong and Hojoung Lee (2010) Enhanced drought tolerance in Arabidopsis via genetic manipulation aimed at the reduction of glucosamine-induced ROS generation. Plant Molecular BIology (in press)
     
     Yerim Kwon, Jee Eun Oh, Hana Noh, Suk-Whan Hong, Seonh Hee Bhoo and Hojoung Lee (2010) The ethylene signaling pathway has a negative impact on sucrose-induced anthocyanin accumulation in Arabidopsis. J. Plant Research. [Epub ahead of print]
     
     Jee Eun Oh, Md. Aktar Hossain, Hana Noh, Suk-whan Hong, Hojoung Lee (2010) The ectopic expression of MSR4 , methionine sulfoxide reductase 4 , results in the enhanced growth performance in Arabidopsis . Plant science (in press)
     
     Aktar Hossain M, Noh HN, Kim KI, Koh EJ, Wi SG, Bae HJ, Hong SW and  Lee H (2010) Mutation of the chitinase-like protein encoding AtCTL2 gene enhances lignin accumulation in dark grown Arabidopsis. J Plant Physiology. 15;167(8):650-8
     
    2009
     
     Md. Aktar Hossain, Sooah Kim, Kyoung Heon Kim, Hojoung Lee (2009)  Flavonoid compounds are enriched in lemon balm (Melissa officinalis) leaves by a high level of sucrose and confer increased antioxidant activity. Hortscience 44(7):1-7
     
     Koh EJ, Kwin YR, Kim KI, Hong SW, Lee H (2009) Altered ARA2 (Rab1a) expression in Arabidopsis reveals the involvement of a Rab/YPT family member in auxin-mediated responses. Plant Molecular Biology 70(1-2):113-22
     
     Seung-won Choi, Ye Rim Kwon, Md. Aktar Hossain, SukWhan Hong, Byeong-ha Lee and Hojoung Lee (2009) A mutation in ELA1, an age-dependent negative regulator of PAP1/MYB75, causes UV- and cold stress-tolerance in Arabidopsis thalina seedlings. Plant Science 678-686
     
     Hyun-Woo ju, Sun-Hee Kim, Kang-il Kim, Eun-Ji Koh, Suk-Whan Hong, Hojoung Lee  (2009) Glucosamine causes overproduction of reactive oxygen species, leading to repression of hypocotyl elongation through hexokinase-mediated mechanism in Arabidopsis. Journal of Plant Physiology 166:203-12
     
     2008
     
     Eun-Ji Koh, Sung June Lee, Suk-Whan Hong, Hoi Seon Lee, and Hojoung Lee (2008) The ABA effect on the accumulation of an inertase inhibitor transcript that is driven by the CAMV35S promoter in Arabidopsis. Molecules and Cells 26:236-42
     
     Ye-Rim Kwon, hee-Jin Lee, Kyeong Heon Kim, Suk-Whan Hong, Sung June Lee, and Hojoung Lee (2008) Ectopic expression of EXPANSIN3 or EXPANSIN-b1 causes enhanced hormone and salt stress sensitivity in Arabidopsis. Biotechnology Letters 30:1281-8
     
    2007
     
     Ye-Rim Kwon, Sun-Hee Kin, Moon-Soo Jung, Mi-Sook Kim, Jee-Eun Oh, Hyun-Woo ju, Kang-il Kim, Elizabeth Vierling, Hojoung Lee and Suk-Whan Hong (2007) Arabidopsis hot2 encodes an endochitinase-like protein that is essential for tolerance to heat, salt and drought stresses. The Plant Journal 49, 184-193
      
     Hyong Seok Park, hee Jin Lee, Min Hye Shin, Kwang-Won lee, Hojoung Lee , Young-Suk Kim, Kwang Ok Kim and Kyeong Heon Kim (2007) Effects of cosolvents on the decffeination of green tea by supercritical carbon dioxide. Food Chemistry 105:1011-1017
     
    2006
     
     Mottler R, kim Y, Song L, Coutu J, Coutu A, Ciftci-Yilmaz S, lee H , Stevenson B, Zhu JK. (2006) Gain- and loss-os-function mutations in Zat10 enhance the tolerance of plants to abiotic stress. FEBS Lett 580, 6537-6542 
     
     EJ Koh, WY Song, Y Lee, KH Kim, K Kim, N Chung, KW Lee, SK Hong, H lee (2006) Expression of yeast cadmium factor1 (YCF1) confers salt tolerance to Arabidopsis thaliana. Plant Science 170:534-541
     

     

  • Research

    Research Topic 
     
    ● Plant abiotic stress signal transduction 
     
    ● Auxin signal transduction 
     
    ● Flavonoid biosynthesis 
     
      
    Lab Profile 
     
    식물의 환경스트레스는 산화스트레스와 밀접한 관계를 가지고 있는 데 그 이유는 식물이 합성해내는 각종 이차대사산물들이 식물의 산화스트레스를 억제하여 환경스트레스 노출 시에 저항성을 부여하는 물질로 기능하기 때문이다. 
     
    지금까지의 국내외 연구를 살펴보면 식물의 환경스트레스 신호 전달 체계 자체의 이해를 통한 신호전달 인자의 유전자원 확보와 그의 기능 규명에 초점이 맞추어져 왔으며 모델식물에서 확보된 이들 전사조절자의 경제작물로의 도입 및 그 특성 연구가 한창 진행되고 있는 단계이다. 
     
    본 연구실은 식물의 환경스트레스를 억제시킬 수 있는 각종 이차대사산물의 새로운 전사조절 관련 유전자들의 발견 및 그의 식물 형질전환체에 연구 목표를 두고 있으며 궁극적으로는 이들 유전자원을 활용한 작물의 내재해성 형질전환체의 생산과 그 효용성을 연구하고자 한다. 

     

  • Teaching

    준비 중입니다.

  • Lab Members

    준비 중입니다.