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간호대학

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소개

Prof. 설근희

E-mail: ghseol@korea.ac.kr
Tel: 82-2-3290-4922

 

  • About Professor
  • Curriculum vitae
  • Publication
  • Research
  • Teaching
  • Lab Members
  • Profile

     
    Geun Hee Seol, RN, PhD. (설근희)
     
    Professor
    Department of Basic Nursing Science, School of Nursing
    Korea University
    E-mail: ghseol@korea.ac.kr | Tel: 82-2-3290-4922
  • Curriculum

    education & training

    Post-Doctoral Fellow in Neuroscience, Mind/Brain Institute, Dept. of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA. 2006
    Ph.D. in Physiology, Dept. of Physiology, Ewha Womans University School of Medicine, Seoul, Korea. 2004
    M.S. in Physiology, Dept. of Physiology, Ewha Womans University School of Medicine, Seoul, Korea. 2001
    B.S. in Nursing, Dept. of Nursing, Korea University School of Medicine, Seoul, Korea. 1996
     

     

    Professional Experiences

    2015 -Present: Reviewer, Oxidative Medicine and Cellular Longevity
    2015 -Present: Reviewer, Journal of Pharmacy and Pharmacology
    2015- Present : Professor, Dept. of Nursing, Korea University School of Nursing, Korea       
    2015 -Present: Reviewer, Planta Media           
    2015 -Present: Reviewer, Flavour and Frangrance Journal
    2015 -Present: Reviewer, Phytotherapy Research
    2015 -Present: Reviewer, Pharmaceutical Biology
    2015 -Present: Director, College of Nursing, Korea University
    2015 -Present: Reviewer, Asian Nursing Research
    2015 -Present: Vice president, Korean Educational Association of Integrative Medicine
    2014 -Present: Reviewer, Phytomedicine
    2014 -Present: Reviewer, Journal of Cardiovascular Pharmacology
    2014 -Present: Reviewer , Korean Journal of Physiology & Pharmacology
    2014: Lead Guest Editor , Neural Plasticity
    2014 -Present: Reviewer , Medicinal Chemistry
    2013-Present: Reviewer , Evidence-Based Complementary and Alternative Medicine
    2013 -Present: Reviewer, Journal of Alternative and Complementary Medicine
    2013 -Present: Editor and Reviewer , Korean Journal of Human Development
    2012 -Present: Reviewer , Neuroscience Letters
    2012 -Present: Editor and Reviewer , Korean Journal of Stress Research
    2012 -Present: Education Director , Korean Educational Association of Integrative Medicine
    2011 -Present: Counselor, Psychologic Affairs from Korea Psychology Counseling Association
    2011 -Present: Reviewer , Journal of Korean Academy of Nursing
    2010-2015: Associate Professor, Dept. of Nursing, Korea University School of Nursing, Korea
    200 9 -Present: Reviewer , Journal of Korean Biological Nursing Science
    2007 -Present: Reviewer , Journal of Korean Gerontological Nursing
    2010 -2012: Academic Director , Korean Educational Association of Integrative Medicine
    2008 - 2010: Publication Director , Korean Educational Association of Integrative Medicine
    2006-2010: Assistant Professor, Dept. of Nursing, Korea University School of Nursing, Korea
    2006-2006: Adjunct Instructor, Dept. of Nursing, Korea University School of Nursing, Korea
    2006-2006: Post-doctoral Fellow, Dept. of Physiology, Eulji University School of Medicine, Korea
    2004-2006: Post-doctoral Fellow, Mind/Brain Institute, Dept. of Neuroscience, Johns Hopkins University School of Medicine, USA
    2002-2003: Adjunct Instructor, Dept. of Nursing, Dankook University School of Medicine, Korea
    1996-1998: Nurse, Dept. of Psychiatry, Korean University Anam Hospital
     

     

    Honors and Awards

    2013 “ 명강의상 ” Best Teaching (Myoung) Award, Korea University The Graduate School of Education, Spring 2013
    2013 Excellent Paper Award, Korean Society of Stress Medicine Domestic Conference
    2013 Poster Award, Korean Society of Adult Nursing International Conference
    2012 “ 석탑강의상 ” Outstanding Teaching (Seok-tap) Award, Korea University, Fall 2011
    2011 Award Certificate, Korean Educational Association of Integrative Medicine
    2011 The Marquis Who’s Who in the World Publications
    2011 “ 명강의상 ” Best Teaching (Myoung) Award, Korea University The Graduate School of Education, Spring 2011
    2011 “ 석탑강의상 ” Outstanding Teaching (Seok-tap) Award, Korea University, Fall 2010 
    2011- Present: Being listed for inclusion in ‘Marquis Who’s Who in the World 2011’ ( 세계인명사전등재 )
    2009 “ 석탑강의상 ” Outstanding Teaching (Seok-tap) Award, Korea University, Fall 2008
    2008 Poster Award, The 13th Congress of the Asian College of Psychosomatic Medicine

     

  • Publications

    Han AY, Lee HS, Seol GH. (2016) Foeniculum vulgare Mill. increases cytosolic Ca²⁺ concentration and inhibits store-operated Ca²⁺ entry in vascular endothelial cells. Biomed Pharmacother. 84: 800-805

    Kang P, Ryu KH, Lee JM, Kim HK, Seol GH. (2016) Endothelium- and smooth muscle-dependent vasodilator effects of Citrus aurantium L. var. amara: Focus on Ca2+ modulation. Biomed Pharmacother. 82: 467-471

    Park H, Seol GH, Ryu S, Choi IY. (2016) Neuroprotective effects of (-)-linalool against oxygen-glucose deprivation-induced neuronal injury. Arch Pharm Res . 3 9( 4): 555-564
     
    Seol GH , Kang P, Lee HS, Seol GH . (2016) A ntioxidant activity of linalool in patients with carpal tunnel syndrome . BMC Neurology. 16 (1): 17
     
    Hwang MJ, Seol GH. (2015) Cerebral oxygenation and pain of heel blood sampling using manual and automatic lancets in premature infants . J Perinat Neonatal Nurs . 29( 4): 356-362 
     
    Kim KY, Lee HS, Seol GH. (2015) Eucalyptol suppresses matrix metalloproteinase-9 expression through an extracellular signal-regulated kinase-dependent nuclear factor-kappa B pathway to exert anti-inflammatory effects in an acute lung inflammation model . J Pharm Pharmacol. 67(8): 1066-1074
     
    Kim KY, Lee HS, Min SS, Seol GH. (2015) Neuroprotective Effect of (-)-Linalool Against Sodium Nitroprusside-Induced Cytotoxicity . Medicinal Chemistry. 5(4): 178-182 
     
    Lee HS, Kang P, Kim KY, Seol GH. (2015) Foeniculum vulgare Mill. Protects against Lipopolysaccharide-induced Acute Lung Injury in Mice through ERK-dependent NF-kB Activ ation . Korean J Physiol Pharmacol. 19(2): 183-189
     
    Kang P, Seol GH. (2015) Linalool elicits vasorelaxation of mouse aortae through activation of guanylyl cyclase and K+ channels. J Pharm Pharmacol. 67(5): 714-719
     
    Yang HJ, Kim KY, Kang P, Lee HS, Seol GH. (2014) Effects of Salvia sclarea on chronic immobilization stress induced endothelial dysfunction in rats. BMC Complement Altern Med. 14(1): 396 
     
    Ryu S, Park H, Seol GH, Choi IY. (2014) 1,8-Cineole ameliorates oxygen-glucose deprivation/reoxygenation-induced ischemic injury by reducing oxidative stress in rat cortical neuron/glia. J Pharm Pharmacol. 66(12): 1818-1826
     
    Kim KY, Seo HJ, Min SS, Park M, Seol GH. (2014) The effect of 1,8-cineole inhalation on preoperative anxiety: a randomized clinical trial. Evid Based Complement Alternat Med . 2014: 820126
     
    Ryu S, Seol GH , Park H, Choi IY. (2014) Trans-anethole protects cortical neuronal cells against oxygen-glucose deprivation/reoxygenation. Neurol Sci. 35: 1541-1547
     
    Choi SY, Kang P, Lee HS, Seol GH. (2014) Effects of Inhalation of Essential Oil of Citrus aurantium L. var. amara on Menopausal Symptoms, Stress, and Estrogen in Postmenopausal Women : A Randomized Controlled Trial. Evid Based Complement Alternat Med . 2014: 756518
     
    Moon HK, Kang P, Lee HS, Min SS, Seol GH . (2014) Effects of 1,8-Cineole on Hypertension Induced by Chronic Exposure to Nicotine in Rats. J Pharm Pharmacol. 66(5): 688-693
     
    Kang P, Suh SH, Min SS, Seol GH . (2013) Citrus bergamia Risso elevated intracellular Ca 2+ in human endothelial cells due to release of Ca2+ from primary intracellular stores. Evid Based Complement Alternat Med . 2013 : 759615
     
    Kang P, Kim KY, Lee HS, Min SS, Seol GH . (2013) Anti-inflammatory effects of anethole in lipopolysaccharide-induced acute lung injury in mice . Life Sci . 93(24): 955-961
     
    Seol GH , Lee YH, Kang P, You JH, Park M, Min SS. (2013) Randomized controlled trial for Salvia sclarea or Lavandula angustifolia: Differential effects on blood pressure in female patients with urinary incontinence undergoing urodynamic examination. J Altern Complement Med. 19(7): 664-670
     
    Kang P, Suh SH, Min SS, Seol GH. (2013) The essential oil Citrus bergamia Risso induces vasorelaxation of mouse aorta by activating K + channels and inhibiting Ca 2+ influx. J Pharm Pharmacol. 65(5): 745-749
     
    You JH, Kang P, Min SS, Seol GH. (2013) Bergamot essential oil differentially modulates intracellular Ca 2+ levels in vascular endothelial and smooth muscle cells: a new finding seen with Fure-2. J Cardiovasc Pharm. 61(4): 324-328
     
    Jun YS, Kang P, Min SS, Lee JM, Kim HK, Seol GH. (2013)   Effect of eucalyptus oil inhalation on pain and inflammatory responses after total knee replacement: A randomized clinical trial . Evid Based Complement Alternat Med . 2013: 502727
     
    Kim EC, Lee MJ, Shin SY, Seol GH, Han SH, Yee J, Kim C, Min SS. (2013) Phorbol 12-myristate 13-acetate enhances long-term potentiation through activation of a protein kinase Cδ and ε in hippocampus. Korean J Physiol Pharmacol . 17 (1): 51-56
     
    Kim H, Han SH, Quan HY, Jung YJ, An J, Kang P, Park JB, Yoon BJ, Seol GH , Min SS. (2012) Bryostatin-1 promotes long-term potentiation via activation of PKCα and PKCε in the hippocampus. Neuroscience 226: 348-355
     
    Kang P, Jung KM, Min SS, Seol GH . (2012) Effect of basil essential oil-inhalation on pain, anxiety and vital sign in patients with chronic low back pain before spine surgery: A double-blind, randomized controlled trial. Korean J Str Res. 20(3): 169-178
     
    Min SS, An J, Lee JH, Seol GH, Im JH, Kim HS, Baik TK, Woo RS. (2011) Neuregulin-1 prevents amyloid β-induced impairment of long-term potentiation in hippocampal slices via ErbB4. Neurosci Lett . 505 (1): 6-9
     
    Seol GH, Jung MH. (2011) Effect of bergamot essential oil-inhalation on chronic pain after surgery for lumbar spinal stenosis. J Korean Biol Nurs Sci. 13(2): 156-163
     
    You JH, Kim MY, Moon HK, Min SS, Seol GH. (2011) Effect of clary sage-inhalation on pain and stress during the treatment of periodontitis. J Korean Acad Oral Health. 35(1): 32-40
     
    Seol GH , Shim HS, Kim PJ, Moon HK, Lee KH, Shim I, Suh SH, Min SS. (2010) Antidepressant-like effect of Salvia sclarea is explained by modulation of dopamine activities in rats. J Ethnopharmacol . 130(1):187-190
     
    Min SS , Han SH , Yee J , Kim C , Seol GH , Im JH , Kim HT , Lee KC , Kim HY , Lee MJ . (2009) Antinociceptive effects of the essential Oil of Ocimum basilicum in mice. Korean J Pain. 22(3): 206-209
     
    Zhang GH, Min SS, Seol GH, Lee KS, Han H, Kim YI, Han HC. (2009) Inhibition of the N-methyl-D-aspartate receptor unmasks the antinociception of endogenous opioids in the periphery. Pain 143(3): 233-237
     
    Min SS, Quan HY, Ma J, Han JS, Jeon BH,Seol GH. (2009) Chronic brain inflammation impairs two forms of long-term potentiation in the rat hippocampal CA1 area. Neurosci Lett . 456(1): 20-24
     
    Min SS, Quan HY, Ma J, Lee KH, Back SK, Na HS, Han SH, Yee JY, Kim C, Han JS, Seol GH. (2009) Impairment of long-term depression induced by chronic brain inflammation in rats. Biochem Biophys Res Commun . 383(1):93-97
     
    Lee MJ , Shim HS, Seo l GH , Kim PJ, Han SH , Yee J , Kim C , Lee KC , Kim HY , Min SS . (2008) Effects of intra-articular injection of agmatine and clonidine into the knee joint cavity on the induction and maintenance of arthritic pain in rats. Korean J Anesthesiol. 54(6): 656-661
     
    Liang GH, Kim JA, Seol GH, Choi S, Suh SH. (2008) The Na+/Ca2+exchanger inhibitor KB-R7943 activates large-conductance Ca2+-activated K+ channels in endothelial and vascular smooth muscle cells. Eur J Pharmacol . 582(1-3): 35-41
     
    Seol GH , Ziburkus J, Huang S, Song L, Kim IT, Takamiya K, Huganir RL, Lee HK, Kirkwood A. (2007) Neuromodulators control the polarity of spike-timing-dependent synaptic plasticity. Neuron 55(6): 919-929
     
    Song JA, Jang SO, Lim YJ, Lee SJ, Kim SY, Seol GH. (2007) Factors affecting loneliness in community dwelling Korean elders. J Korean Acad Fundam Nurs. 14(3): 371-381
     
    Choi SY, Chang J, Jiang B, Seol GH, Min SS, Han JS, Shin HS, Gallagher M, Kirkwood A. (2005) Multiple receptors coupled to phospholipase C gate long-term depression in visual cortex. J Neurosci . 25(49): 11433-11443
     
    Seol GH , Kim MY, Liang GH, Kim JA, Kim YJ, Oh S, Suh SH. (2005) Sphingosine-1-phosphate – induced intracellular Ca2+ mobilization in human endothelial cells. Endothelium 12(5) 263-267
     
    Kim MY, Seol GH, Liang GH, Kim JA, Suh SH. (2005) Na+-K+ pump activation inhibits endothelium-dependent relaxation by activating the forward mode of Na+/Ca2+ exchanger in mouse aorta. Am J Physiol Heart Circ Physiol. 289(5): H2020-2029
     
    Seol GH , Ahn SC, Kim JA, Nilius B, Suh SH. (2004) Inhibition of endothelium-dependent vasorelaxation by extracellular K+: a novel controlling signal for vascular contractility. Am J Physiol Heart Circ Physiol. 286(1): H329-339
     
    Ahn SC, Seol GH, Kim JA, Suh SH. (2004) Characteristics and a functional implication of Ca2+-activated K+ current in mouse aortic endothelial cells. Pflugers Arch. 447(4): 426-435
     
    Jeon SH, Seol GH, Suh SH, Park SH. (2004) Nitric oxide-induced intracellular Ca2+ modulation in macrovascular endothelial cells. Korean Circulation J. 34(9): 600-609
     
    You JY, Seol GH, Suh SH, Ahn JH. (2004) Regulatory mechanism of vascular contractility by extracellular K+: effect on endothelium-dependent relaxation and smooth muscle contractility. Korean J Thorac Cardiovasc Surg. 37(3): 210-219
     
    Seol GH, Kim J, Cho SH, Kim WK, Kim JW, Kim SJ. (2001) The inhibitory effect of opioid on the hyperpolarization-activated cation currents in rat substantia gelatinosa neurons. Korean J Physiol Pharmacol. 5(5):373-380
     
     

     

    Patents

    (2015) Pharmaceutical Composition for Preventing or Treating Diabetes Comprising Linalyl Acetate, 특허출원 
     

     

    Books

    (2014) Essentials of Anatomy and Physiology, 8 th ed., Hyunmoonsa
     
     
    (2014) Human Diseases, 7 th ed., Bioscience
     
     
    (2014) Introduction to Clinical Pharmacology, 7 th ed., Elsevier Korea
     
     
    (2013) Color Atlas of Pathophysiology, Seoulmedmedia
     
     
    (2013) Pathophysiology, Jungmunkag
     
     
    (2013) Essential of medical terminology, Medicean
     
     
    (2010) Pharmacology, Jungmunkag
     
     
    (2009) Human Diseases, 6 th ed., Bioscience
     
     
    (2009) Comprehensive Stress Management, Academia

     

  • Research

    Research Interests

    Our laboratory is interested in exploring the cellular and molecular mechanisms of neuronal plasticity underlying learning and memory. Dr. Geun-Hee Seol currently focuses upon the physiological roles of aromatic essential oils in neuronal cells as well as endothelial cells. In more detail, we explore novel biochemical mechanisms of aromatic essential oils which can control somatic diseases such as hypertension, depression. Current emphasis of laboratory animal studies focuses upon the experimental analysis of the basic mechanisms of aromatic essential oils with the objective of evaluating compounds. To d evelop aromatheraphy that has aromatic effect without adverse effects after revealing their mechanisms of action, we also study the action of aromatic essential oils in pain related clinical diseases. In addition, we are also interested in elucidating the role of calcium in the regulation of neuronal plasticity.
    Combining various techniques, such as electrophysiology, cellular & molecular biology, calcium imaging and behavioral neuroscience, we are investigat ing to understand molecule-to-behavior pathways using mice or rats . Main topics of our research include 1) neural mechanisms of learning and memory , 2) action mechanisms of aromatic essential oils , and 3) intracellular calcium signaling

     

    Research Project as Principal Investigator

    2016.11-2018.10 “Study of control mechanisms of compounds from aromatic natural product on hypoxia-induced cerebrovascular injury” supported by Basic Science Research Program through National Research Foundation of Korea (NRF)


    2016.3 -2019.3 “Study for clinical intervention and cardiovascular action mechanism of active compound from Codonopsis lanceolata” supported by the National Research Foundation of Korea Forest Service (KFS)


    2012.5 -2015.4 “Study for the inhibitory effect of aroma on the ischemic brain injury and changes of synaptic plasticity” supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP)
     
    2010.5 -2013.4 “Study for the mechanism of analgesic effect with aroma in inflammatory pain model” supported by Basic Science Research Program through National Research Foundation of Korea (NRF)
     
    2012.3-2013.2 “Effect of basil-inhalation on pain in patients with chronic low back pain” supported by Nursing Research Institute Grant, Korea University
     
    2010.3-2011.2 “ Effect of Aroma Essential Oil on Endothelial Ca 2+ signaling ” supported by a Korea University Grant
     
    2009.5 -2012.4 “Study for the mechanism of antihypertensive of aroma in vascular tone” supported by Basic Science Research Program through National Research Foundation of Korea (NRF)
     
    2007.5 -2010.2 “Study for the mechanism of anti-depression and anti-stress of aroma” supported by Korean Science and Engineering Foundation (KOSEF)
     
    2006.9-2007.8 “The regulating mechanism of synaptic plasticity in the cerebral cortex” supported by a Korea University Grant
     
    2004.4 -2005.3 “ A study of correlation between cognitive function and hippocampal LTD in aged rats” supported by Korean Science and Engineering Foundation (KOSEF)

     

     

  • Teaching

    Undergraduate Program: 
    · Basic Nursing Science I (기초간호과학I) · Basic Nursing Science Lab I (기초간호과학실습I) · Basic Nursing Science II (기초간호과학II) · Basic Nursing Science Lab II (기초간호과학실습II) · Basic Nursing Science III (기초간호과학III) · Basic Nursing Science IV (기초간호과학IV) 

    Graduate Program: 
     · Pathophysiology (병태생리학) · Advanced Basic Nursing Science (상급기초간호과학) · Seminar in Basic Nursing Science (기초간호과학세미나) · Quantitative Research Methods in Nursing (양적간호교육연구)

  • Lab Members

    기초간호과학연구실

     

    Current members:

    · 이희수(연구원) 

    · 강푸름(박사과정) 

    · 이성숙(박사과정) 

    · 한아영(박사과정) 

    · HSIEH YU SHAN (박사과정)

    · 이수연(석사과정)

    · 유강현(석사과정)

    · 서은혜(석사과정)

    · 권순호(석사과정)

    · 신유경(석사과정) 

     

    Former members:

    · 유지혜(석사)

    · 문혜경(박사) 

    · 김주리(석사) 

    · 양효정(석사) 

    · 최인녕(연구교수) 

    · 김가영(연구교수) 

    준비중입니다