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고려대학교 교수소개

Knowledge & Innovation

소개

Prof. 정남현

Tel:  02-3290-3026

E-mail: nchung@korea.ac.kr

  • About Professor
  • Curriculum Vitae
  • Publication
  • Research
  • Teaching
  • Lab Members
  • Profile

    Korea University, Anam Campus, College of Life Sciences and Biotechnology, West Building 511

  • Curriculum Vitae

    Education

    • 1980.3 - 1984.2 고려대학교 / 농화학, 학사
    • 1984.3 - 1986.2 고려대학교 / 생화학 및 발효화학, 석사
    • 1990.9 - 1995.8 유타 주립대학교 / 생화학, 박사

    Professional Experiences

    • 2007.3 - 현재 교수 / 고려대학교 생명공학부
    • 2006.3 - 2007.2 부교수 / 고려대학교 생명공학부
    • 2002.3 - 2006.2 부교수 / 고려대학교 생명유전공학부
    • 2001.3 - 2002.2 조교수 / 고려대학교 생명유전공학부
    • 2000.3 - 2001.2 조교수 / 고려대학교 응용생명환경학과
    • 1998.9 - 2000.2 연구원 / Laboratory of Biochemistry, NHLBI, NIH
    • 1995.6 - 1998.8 박사 후 연구원 / 코넬대학교 환경독성 프로그램
    • 1988.1 - 1990.7 선임연구원 / 태평양 화학 중앙연구소

    Academy

    • 2013.01-현재 한국분자세포생물학회, 편집부원장
    • 2012.01-현재 한국분자세포생물학회, 정회원
    • 2009.01-현재 한국생물공학회, 정회원
    • 2002.10-현재 한국환경독성학회, 정회원
    • 2000.06-현재 한국미생물․생명공학회, 정회원
    • 2000.03-현재 한국응용생명화학회, 정회원/이사/부회장/운영위원
  • Publication

    2019

     

    Lee, D. G., Go, E. B., Lee, M., Pak, P. J., Kim, J. S., & Chung, N. (2019). Gold nanoparticles conjugated with resveratrol induce cell cycle arrest in MCF-7 cell lines. Appl Bio Chem, 62(1), 33.

    2018

     

    Han, S., Choi, E. K., Park, W., Yi, C., & Chung, N. (2019). Effectiveness of expanded clay as a bacteria carrier for self-healing concrete. Appl Bio Chem, 62(1), 19.

     

    Lee, J. Y., Kim, M. S., Ju, J. E., Lee, M. S., Chung, N., & Jeong, Y. K. (2018). Simvastatin enhances the radiosensitivity of p53‑deficient cells via inhibition of mouse double minute 2 homolog. Int Jor onco 52(1), 211-218.

    2017

    • Lee, J. Y., Kim, M. S., Lee, M. S., Ju, J. E., Chung, N., & Jeong, Y. K. (2017). Digoxin enhances radiation response in radioresistant A549 cells by reducing protein phosphatase 2A. Biosci Rep, 37(6).

    • Lee, J. W., Kim, Y. I., Im, C. N., Kim, S. W., Kim, S. J., Min, S., Joo, Y. H., Yim, S. V., & Chung, N. (2017). Grape Seed Proanthocyanidin Inhibits Mucin Synthesis and Viral Replication by Suppression of AP-1 and NF-kappaB via p38 MAPKs/JNK Signaling Pathways in Respiratory Syncytial Virus-Infected A549 Cells. J Agric Food Chem, 65(22), 4472-4483.

    • Cho, M., Lee, H., Hwang, M. H., Cheong, Y. K., Kang, C. S., Lee, N. T., & Chung, N. (2017). Differential induction of allergy responses by low molecular weight wheat proteins from six wheat cultivars. Journal of Applied Biological Chemistry, 60(1), 55-59.

    • Hwang, M. H., Lee, D. G., Go, E. B., Cho, M., Park, Y. S., & Chung, N. (2017). Anti-diabetic effect of magnesium salt extracts from deep-sea water in C57BLKS/J-db/db mice. Applied Biological Chemistry, 60(1), 95-99.

    • Lee, H., Hwang, M. H., Cho, M., Lee, D. G., Go, E. B., Cheong, Y. K., Kang, C. S., Lee, N. T., & Chung, N. (2017). Comparison of blood glucose levels and allergic responses on treatment with six wheat cultivars. Applied Biological Chemistry, 60(1), 11-16.

    2016

    • Cho, Y. C., Pak, P. J., Joo, Y. H., Lee, H. S., & Chung, N. (2016). In vitro and in vivo comparison of the immunotoxicity of single- and multi-layered graphene oxides with or without pluronic F-127. Scientific Reports, 6.

    • Pak, P. J., Go, E. B., Hwang, M. H., Lee, D. G., Cho, M. J., Joo, Y. H., & Chung, N. (2016). Evaluation of the cytotoxicity of gold nanoparticle-quercetin complex and its potential as a drug delivery vesicle. Journal of Applied Biological Chemistry, 59(2), 145-147.

    • Pak, P. J., Kang, B. H., Park, S. H., Sung, J. H., Joo, Y. H., Jung, S. H., & Chung, N. (2016). Antitumor effects of herbal mixture extract in the pancreatic adenocarcinoma cell line PANC1. Oncology Reports, 36(5), 2875-2883.

    • Joo, Y. H., Lee, D. H., Lee, N. T., & Chung, N. (2016). Model development for prediction of the allergic response to the wheat proteins ω-5 gliadin and HMW-glutenin. Applied Biological Chemistry, 59(6), 827-831.

    • Kim, J. H., Pak, P. J., Kim, J. G., Cheong, Y. K., Kang, C. S., Lee, N. T., & Chung, N. (2016). Comparison of allergy-inducible wheat protein contents among imported and domestic wheat flours in Korea. Journal of Applied Biological Chemistry, 59(1), 1-3.

    2014~2015

    • Park, S. H., Sung, J. H., Kim, E. J., & Chung, N. (2015). Berberine induces apoptosis via ROS generation in PANC-1 and MIA-PaCa2 pancreatic cell lines. Brazilian Journal of Medical and Biological Research, 48(2), 111-119.

    • Pak, P. J., Kang, B. H., & Chung, N. (2015). Silver materials induce differential cytotoxicity and pulmonary toxicity based on size and shape. Journal of Applied Biological Chemistry, 58(2), 113-116.

    • Jung, H. J., Pak, P. J., Park, S. H., Ju, J. E., Kim, J. S., Lee, H. S., & Chung, N. (2014). Silver Wire Amplifies the Signaling Mechanism for IL-1beta Production More Than Silver Submicroparticles in Human Monocytic THP-1 Cells. Plos One, 9(11).

    • Kim, T. G., Cho, Y. C., Chun, B. H., Park, S. H., Lee, H. S., & Chung, N. (2014). Poly-gamma-glutamic acid enhances the quality of recombant erythropoietin produced by CHO cells. Biotechnology & Biotechnological Equipment, 28(2), 350-354.

    • Lee, J. H., Ju, J. E., Kim, B. I., Pak, P. J., Choi, E. K., Lee, H. S., & Chung, N. (2014). Rod-Shaped Iron Oxide Nanoparticles Are More Toxic Than Sphere-Shaped Nanoparticles to Murine Macrophage Cells. Environmental Toxicology and Chemistry, 33(12), 2759-2766.

    • Park, S. H., Sung, J. H., & Chung, N. (2014). Berberine diminishes side population and down-regulates stem cell-associated genes in the pancreatic cancer cell lines PANC-1 and MIA PaCa-2. Molecular and Cellular Biochemistry, 394(1-2), 209-215.

    • Kim, T. G., Cho, Y. C., Chun, B. H., Park, S. H., Lee, H. S., & Chung, N. (2014). Poly-gamma-glutamic acid enhances the quality of recombant erythropoietin produced by CHO cells. Biotechnology & Biotechnological Equipment, 28(2), 350-354
  • Research

    Cancer/Nanoscience
    The researches for optimizing cancer therapy by conjugation of herb-derived compound and metal nanoparticle.

    •   - Raising the technical and academic standard of one more step in cancer treatment by fusing nanotechnology with oriental medicine that have been judged strengths of Korea.
    •   - Selecting and evaluating the toxic effects of herb-derived compound and synthesized nanoparticle.
    •   - Cancer targeting and safety test in vivo based on the last research.

    Genomics
    Development of abiotic and biotic stress tolerant synthetic hexaploid wheat (SHW) breeding materials against climate changes

    •   - Screen the abiotic and biotic stress tolerant synthetic wheat genes from T. durum and Ae. tauschii gene resources
    •   - Select the quality resources through genomics like SNP marker and diverse molecular techniques.

    Plant growth promoting rhizobacteria(PGPR)
    Development of bio-fertilizers containing PGPR and plant growth stimulants to enhance organic cultivation efficacy of horticultural crops

    •   - Screening and isolation of PGPR from horticultural rhizosphere
    •   - Development of plant growth stimulation effective material extraction technologies of natural and functional biomaterials
    •   - Examination of biomaterial extracts on horticultural crop growth stimulation

     

     

  • Teaching

    준비중입니다.

  • Lab Members

    Lab Members
    박표준, Pyo June Pak (MS/Ph.D course) twins0815@korea.ac.kr
    주용훈, Yong Hun Joo (Ph.D course) imperiwose@nate.com
    이혜리, Hyeri Lee (MS/Ph.D course) hyeri730@gmail.com
    이동건, Dong Gun Lee (MS/Ph.D course) harry171@naver.com
    이지민, Jimin Lee (MS course) jimin1215@korea.ac.kr
    이상규, Sang Gyu Lee (MS course) dltkdrb5658@naver.com