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고려대학교 교수소개

Knowledge & Innovation

소개

Prof. 안지훈

Tel: 02-3290-3451

Fax: 02-927-9028

  • About Professor
  • Curriculum Vitae
  • Publications
  • Research
  • Invited Talks
  • Lab Members

갤러리게시판

  • Profile

    Prof. Ji Hoon Ahn received his Ph.D. from Seoul National University in 1997 and conducted a study on the control of flowering time in Arabidopsis in the Detlef Weigel Lab of The Salk Institute for Biological Studies (La Jolla, CA) from 1998 to 2001. He started his own laboratory in Korea University in 2001. Prof. Ahn is interested in understanding the molecular mechanism of the regulation of flowering time by ambient temperature changes in Arabidopsis as a model system. From 2008 to 2017, he led the Ambient Temperature Sensor Research Center (Creative Research Initiative/MOST). From 2017 to 2022, he led a research project funded by the Samsung Science and Technology Foundation. In 2022, he has been re-awarded the Leader Research Grant (formerly Creative Research Initiative) and will lead the research group until 2031.

     

    안지훈은 1997년 서울대학교에서 박사학위를 하고 1998년부터 2001년까지 미국 The Salk Institute for Biological Studies (La Jolla, CA)의 Detlef Weigel Lab에 서 애기장대의 개화시기 조절에 관한 연구를 했다. 주요 연구 관심은 애기장대를 모델로 해서 고등식물체에서 대기온도의 변화를 인지하는 개화 조절과 miRNA에 의해 일어나는 개화시기 조절에 관한 연구이다. 2008년부터 2017년까지 대기온도 센서 연구단 (창의적 연구 진흥 사업/미래창조과학부)을 이끌었으며, 2017년 부터 2022년까지 삼성미래육성재단의 과제를 수행했다. 2022년에  다시 리더연구자 사업(구 창의적 연구 진흥사업)에 선정되어 2031년까지 사업단장을 맡을 계획이다.

     

     

    Inducted into the 'KU Hall of Fame' at Korea University in May 2020

    2020년 5월  고려대학교 'KU 명예의 전당'에 헌액

     

     

     

    Awards

    • Research Areas

     

     

     

    2024 Jan Top 10 Best Practices for Leveraging and Disseminating Research (among top 100 R&D Excellence) KISTEP

    2023 May

    Sudang Award

    Sudang Foundation

    2022 November

    Elected as a Regular Fellow

    Korea Academy of Science and Technology

    2022 May

    Seoktap Research Award

    Korea University

    2021 December

    Academic Award

    Korean Society of Plant Biologists

    2020 May

    Induction into the Hall of Fame 

    Korea University

    2019 December

    Korea Science Award (Presidential Award)

    Korea

    2019 April

    Science Day Award (Prime minister's Award)

    Korea

    2016 June

    Seoktap Research Award

    Korea University

    2015 January

    Academic Award

    Korea University Alumni Association

    2014 December Prime Minister's Award for Science/Technology Creativity Korea
    2014 November Top 50 National Basic Research Achievements Korea
    2014 October Life Science Academic Award Korean Society of Molecular and Cellular Biology
    2014 September Dasan Award MBC
    2014 July National R&D Excellence top 100 Korea
    2014 April Scientist of the Month Award Korea
    2013 November 60th Anniversary Achievement Award Korea University
    2010 October Macrogen Scientist Award Korean Society of Molecular and Cellular Biology
    2004 September Meritorious Scientist Award  Korea

     

     

     

    수상 내역
    연구 분야

    2024년 1월 국가 R&D 우수성과 100선 중 대표적 활용/확산 사례 10선에 선정 (한국과학기술평가원)

    2023년 5월 수당상 수상

    2022년 11월 한국과학기술한림원 정회원으로 선출

    2022년 5월 석탑연구상 (고려대학교)

    2021년 12월 한국식물학회 학술상

    2020년 5월 KU 명예의 전당 헌액 (고려대학교)

    • 2019년 12월 2019년 한국 과학상 (대통령상) (대한민국 정부) 유튜브 링크
    • 2019년 4월 과학의 날 정부 포상 (국무총리상) (대한민국 정부)
    • 2016년 6월 석탑연구상 (고려대학교)
    • 2015년 1월 학술상 (고려대학교 교우회)
    • 2014년 12월 과학기술창의상 국무총리상 (미래창조과학부)
    • 2014년 11월 국가 기초연구 우수 성과 50선 (한국 연구재단/미래창조과학부)
    • 2014년 10월 생명과학 학술상 (한국분자세포생물학회)
    • 2014년 9월 다산대상 (실용과학부문) (MBC)
    • 2014년 7월 국가연구개발 우수성과 100선 (미래창조과학부)
    • 2014년 4월 이달의 과학기술자상 (미래창조과학부)
    • 2013년 11월 60주년 공로상 (고려대학교)
    • 2010년 10월 마크로젠 과학자상 (한국분자세포생물학회)
    • 2004년 9월 과학기술 유공자상 (과학기술부)

     

    교육 분야

    -석탑강의상 (고려대학교 강의 중 상위 5%)

     

    2020년 석탑강의상 (식물발달분자생리학2)

    2020년 석탑강의상 (유전학2)

    2020년 석탑강의상 (식물발달분자생리학1)
    • 2019년 석탑강의상 (식물발달분자생리학2)
    • 2019년 석탑강의상 (식물발달분자생리학1)
    • 2017년 석탑강의상 (식물발달분자생리학1)
    • 2015년 석탑강의상 (식물발달분자생리학2)
    • 2015년 석탑강의상 (식물발달분자생리학1)
    • 2014년 석탑강의상 (식물발달분자생리학1)
    • 2013년 석탑강의상 (식물발달분자생리학2)
    • 2012년 석탑강의상 (식물발달분자생리학2)
    • 2011년 석탑강의상 (식물발달분자생리학1)
    • 2005년 석탑강의상 (유전학)

     

    -우수강의상 (고려대학교 강의 중 상위 20%)

     

    2022년 우수강의상 (식물발달분자생리학2)

    2021년 우수강의상 (유전학2)

    2021년 우수강의상 (유전학1)

    2020년 우수강의상 (유전학1)

    2019년 우수강의상 (유전학2)

    2018년 우수강의상 (식물발달분자생리학2)

    2018년 우수강의상 (식물발달분자생리학1)

    2014년 우수강의상 (식물발달분자생리학2)

    2013년 우수강의상 (식물발달분자생리학1)

    2012년 우수강의상 (식물발달분자생리학2)

  • Curriculum Vitae

    2022-2031 Director, Leader Grant, Ministry of Science and ICT
    2017-2022 Director, Samsung Science & Technology Foundation 

    2008-2017

    Director, Creative Research Initiatives, Ministry of Science, ICT, and Future Planning

    2007-2008

    Visiting Scholar, Center for Genome Research and Biocomputing, Oregon State University, USA

    2003-2008

    Vice director, Plant Signaling Network Research Center, Ministry of Science/Technology

    2001-Present

    Assistant, Associate, Full Professor, Department of Life Sciences, Korea University

    1998-2001

    Research Associate, The Salk Institute for Biological Studies, La Jolla, CA

    The Salk Institute for Biological Sciences, USA

    Postdoctoral

    02/2001

    Molecular Genetics

    Seoul National University, Korea

    Ph.D.

    08/1997

    Molecular Biology

    Seoul National University, Korea

    M.Sc

    02/1993

    Molecular Biology

    Seoul National University, Korea

    B.S.

    02/1988

    Botany

     

  • Publications

    Selected Publications

    (click here to see all publications)

     

    All our 84 papers have been cited 10,212  times (as of 2022-07-17)

     

    Publication
    Suhyun Jin†, Geummin Youn†, Sun Young Kim, Taewook Kang, Hyun-young Shin, Ji-Yul Jung, Pil Joon Seo, and Ji Hoon Ahn (2024) The CUL3A–LFH1–UBC15 ubiquitin ligase complex mediates SHORT VEGETATIVE PHASE degradation to accelerate flowering at high ambient temperature. Plant Communications. https://doi.org/10.1016/j.xplc.2024.100814
    Hendry Susila†, Zeeshan Nasim† , Katarzyna Gawarecka, Ji-Yul Jung, Suhyun Jin, Geummin Youn, and Ji Hoon Ahn (2023) Chloroplasts prevent precocious flowering through a GOLDEN2-LIKE–B-BOX DOMAIN PROTEIN module. Plant Communications. https://doi.org/10.1016/j.xplc.2023.100515

    Suhyun Jin, Sun Young Kim, Hendry Susila, Zeeshan Nasim, Geummin Youn, Ji Hoon Ahn (2022). FLOWERING LOCUS M isoforms differentially affect the subcellular localization and stability of SHORT VEGETATIVE PHASE to regulate temperature-responsive flowering in Arabidopsis. Molecular Plant . 15(11), 1696-1709 https://doi.org/10.1016/j.molp.2022.08.007

     

    This paper has been covered by Spotlight article ( https://www.cell.com/molecular-plant/fulltext/S1674-2052(22)00354-9 )

    Hendry Susila, Snježana Juric´, Lu Liu, Katarzyna Gawarecka, Kyung Sook Chung, Suhyun Jin, Soo-Jin Kim, Zeeshan Nasim, Geummin Youn, Mi Chung Suh, Hao Yu, Ji Hoon Ahn (2021). Florigen sequestration in cellular membranes modulates temperature-responsive flowering. Science . DOI: 10.1126/science.abh4054. Paper link

    *This paper featured in Science perspective

    https://www.science.org/doi/10.1126/science.abl4883

     

    News coverage

    Florigen sequestering in cell membranes modulates temperature-responsive flowering  (phys org) 

    Descubren como las plantas evitan florecer en pleno invierno  (Muy Interesante)

     

    Zeeshan Nasim, Muhammad Fahim, Hocheol Hwang, Hendry Susila, Suhyun Jin, Geummin Youn, Ji Hoon Ahn (2021). Nonsense-mediated mRNA decay modulates Arabidopsis flowering time via the SET DOMAIN GROUP 40–FLOWERING LOCUS C module. Journal of Experimental Botanyhttps://doi.org/10.1093/jxb/erab331 .
    Suhyun Jin and Ji Hoon Ahn (2021). Regulation of Flowering Time by Ambient Temperature: Repressing the Repressors and Activating the Activators.  New Phytologist . 230 (3), 938-942 https://doi.org/10.1111/nph.17217

    Hendry Susila, Zeeshan Nasim, Katarzyna Gawarecka, Ji-Yul Jung, Suhyun Jin, Geummin Youn, and Ji Hoon Ahn (2020) PHOSPHORYLETHANOLAMINE CYTIDYLYLTRANSFERASE 1 modulates flowering in a florigen-independent manner by regulating SVP. Development .

    This paper has been selected as a "Research Highlight" of the issue.

    Suhyun Jin, Zeeshan Nasim, Hendry Susila, and Ji Hoon Ahn (2020) Evolution and functional diversification of FLOWERING LOCUS T/TERMINAL FLOWER 1 family genes in plants. Seminars in Cell and Developmental Biology . https://doi.org/10.1016/j.semcdb.2020.05.007
    Chung-Hee Lee, Soo-Jin Kim, Suhyun Jin, Hendry Susila, Geummin Youn, Zeeshan Nasim, Hemasundar Alavilli, Kyung Sook Chung, Seong Jeon Yoo and Ji Hoon Ahn (2019) Genetic interactions reveal the antagonistic roles of FT/TSF and TFL1 in the determination of inflorescence meristem identity in Arabidopsis. The Plant Journal . 99(3) 452-464. https://doi.org/10.1111/tpj.14335

    Keumbi Hwang, Hendry Susila, Zeeshan Nasim, Ji-Yul Jung and Ji Hoon Ahn (2019) Arabidopsis ABF3 and ABF4 transcription factors act with the NF-YC complex to regulate SOC1 expression and mediate drought-accelerated Flowering. Molecular Plant . 12(4) 489-505  https://doi.org/10.1016/j.molp.2019.01.002

    * This paper was selected as Editor's choice (2019)

    https://www.cell.com/molecular-plant/libraries/editors-choice

    Ji Hoon Ahn and Markus Schmid (2017) Editorial overview: Growth and development: Change in the air: how plants modulate development in the environment. Current Opinion in Plant Biology 35: iv-vi 

    https://doi.org/10.1016/j.pbi.2017.01.003

    Wanhui Kim, Hee-Eun Kim, Ae-Ree Lee, A Rim Jun, Myeong Gyo Jung, Ji Hoon Ahn and Joon-Hwa Lee (2017) Base-pair opening dynamics of primary miR156a using NMR elucidates structural determinants important for its processing level and Leaf Number Phenotype in Arabidopsis. Nucleic Acids Research 45 (2): 875-885

    https://doi.org/10.1093/nar/gkw747

    Hendry Susila, Suhyun Jin, and Ji Hoon Ahn (2016) Light Intensity and Floral Transition: Chloroplast Says "Time to Flower!" Molecular Plant 9 (12), 1551-1553 

    https://doi.org/10.1016/j.molp.2016.10.013

    Wanhui Kim, Hee-Eun Kim, A Rim Jun, Myeong Gyo Jung, Suhyun Jin, Joon-Hwa Lee and Ji Hoon Ahn (2016) Structural determinants of miR156a precursor processing in temperature-responsive flowering in Arabidopsis. Journal of Experimental Botany 67 (15): 4659-4670

    https://doi.org/10.1093/jxb/erw248

    Ji Hoon Ahn (2016) Flowering time: Have florigen, will travel. Nature Plants 2 (6): 16081 (June 3, 2016)

    https://www.nature.com/articles/nplants201681

    Soo-Jin Kim, Sung Myun Hong, Seong Jeon Yoo, Suhyun Moon, Hye Seung Jung and Ji Hoon Ahn (2016) Post-Translational Regulation of FLOWERING LOCUS T Protein in Arabidopsis. Molecular Plant 9 (2): 308-311 (February 1, 2016)

    https://doi.org/10.1016/j.molp.2015.11.001

    Esther Marín-González, Luis Matías-Hernández, Andrea E. Aguilar-Jaramillo, Jeong Hwan Lee, Ji Hoon Ahn, Paula Suárez-López and Soraya Pelaz (2015) SHORT VEGETATIVE PHASE specifically activates TEMPRANILLO2 floral repressor at low ambient temperatures. Plant Physiology 169 (2): 1214-1224 (October 1, 2015)

    https://doi.org/10.1104/pp.15.00570

    Suhyun Jin, Hye Seung Jung, Kyung Sook Chung, Jeong Hwan Lee, and Ji Hoon Ahn (2015) FLOWERING LOCUS T (FT) has higher protein mobility than TWIN SISTER OF FT (TSF). Journal of Experimental Botany 66 (20): 6109-6117 (October 1, 2015)

    https://doi.org/10.1093/jxb/erv326

    Huang-Lung Tsai, Yi-Hang Li, Wen-Ping Hsieh, Meng-Chun Lin, Ji Hoon Ahn and Shu-Hsing Wu (2014) HUA ENHANCER1 Is Involved in Posttranscriptional Regulation of Arabidopsis Photomogenesis. Plant Cell 26 (7) 2858-2872. (July 1, 2014)

    https://doi.org/10.1105/tpc.114.126722

    Jae Yong Ryu, Hyo-Jun Lee, Pil Joon Seo, Jae-Hoon Jung, Ji Hoon Ahn, and Chung-Mo Park (2014) The Arabidopsis Floral Repressor BFT Delays Flowing by Competing with FT for Binding under High Salinity. Molecular Plant 7 (2) 377-387 (February 1, 2014)

    https://doi.org/10.1093/mp/sst114

    Jeong Hwan Lee, Hak-Seung Ryu, Kyung Sook Chung, David Posé, Sonkap Kim, Markus Schmid, and Ji Hoon Ahn (2013) Regulation of Temperature-Responsive Flowering by MADS-Box Transcription Factor Repressors. Science 342 (6158): 628-632 (November 1, 2013) 

    https://doi.org/10.1126/science.1241097
    Abstract    Reprint
    * Featured in a Science Perspective Click Here
    * Editor's Choice in Science Signaling Click Here

    Wanhui Kim, Tae Im Park, Seong Jeon Yoo, A Rim Jun, and Ji Hoon Ahn (2013) Generation and analysis of a complete mutant set of the Arabidopsis FT/TFL1 family of thermo-sensitive flowering regulation. Journal of Experimental Botany 64 (6): 1715-1729. (April, 2013)

    https://doi.org/10.1093/jxb/ert036

    Seong Jeon Yoo, Sung Myun Hong, Hye Seung Jung, and Ji Hoon Ahn * (2013) The Cotyledons Produce Sufficient FT Protein to Induce Flowering: Evidence from Cotyledon Micrografting in Arabidopsis. Plant and Cell Physiology 54 (1): 119-128 (January, 2013)

    https://doi.org/10.1093/pcp/pcs158
    * Selected as an "Editor-in-Chief's Choice of the January Issue"

    Jae Joon Kim, Jeong Hwan Lee, Wanhui Kim, Hye Seung Jun, Peter Huijser, Ji Hoon Ahn (2012) The microRNA156-SQUAMOSA PROMOTER BINDING PROTEIN-LIKE3 Module Regulates Ambient Temperature-Responsive Flowering via FLOWERING LOCUS T in Arabidopsis. Plant Physiol. 159 (1): 461-78 (May, 2012)

    https://doi.org/10.1104/pp.111.192369

    Seong Kwan Yoo, Xuelin Wu, Jong Seob Lee, Ji Hoon Ahn (2011) AGAMOUS-LIKE 6 is a floral promoter that negatively regulates the FLC/MAF clade genes and positively regulates FT in Arabidopsis. Plant Journal 65 (1), 62-76 (January 01, 2011) 

    https://doi.org/10.1111/j.1365-313x.2010.04402.x

    Seong Jeon Yoo, Kyung Sook Chung, Seung Hye Jung, So Yeon Yoo, Jong Seob Lee, Ji Hoon Ahn (2010) BROTHER OF FT (BFT) has TFL1-like activities and functions redundantly with TFL1 in inflorescence meristem development in Arabidopsis. Plant Journal 63 (2), 241-53 (July 01, 2010)

    https://doi.org/10.1111/j.1365-313x.2010.04234.x

    Hanna Lee, Seong Jeon Yoo, Jeong Hwan Lee, Wanhui Kim, Seung Kwan Yoo, Heather Fitzgerald, James C Carrington, Ji Hoon Ahn (2010) Genetic framework for flowering-time regulation by ambient temperature-responsive miRNAs in Arabidopsis. Nucleic Acids Research 38 (9), 3081-3093 (May 01, 2010)

    https://doi.org/10.1093/nar/gkp1240

    * THIS PAPER RANKS AMONG THE TOP 10% HIGHLY CITED PAPERS OF 2010 PUBLISHED IN NUCLEIC ACIDS RESEARCH *

    Taiowa A. Montgomery, Seong Jeon Yoo, Noah Fahlgren, Sunny D. Gilbert, Miya D. Howell, Christopher M. Sullivan, Amanda Alexander, Goretti Nguyen, Edwards Allen, Ji Hoon Ahn and James C. Carrington (2008) AGO1-miR173 complex initiates phased siRNA formation in plants. PNAS 105 (51), 20055-20061 (December 22, 2008)
    https://doi.org/10.1073/pnas.0810241105
    * THIS PAPER RANKS AMONG THE TOP 25% HIGHLY CITED PAPERS OF 2008 PUBLISHED IN PNAS *

    So Yeon Yoo, Yunhee Kim, Soo Young Kim, Jong Seob Lee, and Ji Hoon Ahn (2007) Control of flowering time and cold response by a NAC-domain protein in Arabidopsis. PLoS ONE 2 (7), e642 (July 25, 2007)
    https://doi.org/10.1371/journal.pone.0000642


    * THIS PAPER IS SELECTED AS A HIGHLY VIEWED ARTICLE (> 2,000 VIEWS / YEAR) PUBLISHED IN PLOS ONE *

    Jeong Hwan Lee, Seong Jeon Yoo, Soo Hyun Park, Ildoo Hwang, Jong Seob Lee, and Ji Hoon Ahn (2007) Role of SVP in the control of flowering time by ambient temperature in Arabidopsis. Genes and Development 21 (4), 397-402 (Feb 15, 2007)
    https://doi.org/10.1101%2Fgad.1518407

    *THIS PAPER RANKS THE TOP 5.7% HIGHLY CITED PAPERS OF RESEARCH ARTICLES  PUBLISHED IN GENES & DEVELOPMENT ALL TIME (37 YEARS)


    * THIS PAPER RANKS AMONG THE TOP 20% HIGHLY CITED PAPERS OF 2007 PUBLISHED IN GENES & DEVELOPMENT *

    Ji Hoon Ahn, David J. Miller, Victoria J. Winter, Mark J. Banfield, Jeong Hwan Lee, So Yeon Yoo, Stefan R. Henz, R. Leo Brady, and Detlef Weigel * (2006) A divergent external loop confers antagonistic activity on floral regulators FT and TFL1. EMBO J. 25 (3), 605-614 (Feb 8, 2006)
    https://doi.org/10.1038/sj.emboj.7600950


    * THIS PAPER RANKS AMONG THE TOP 40 HIGHLY CITED PAPERS OF 2006 PUBLISHED IN EMBO JOURNAL *

    Seung Kwan Yoo, Kyung Sook Chung, Joonki Kim, Jeong Hwan Lee, Sung Myun Hong, Seong Jeon Yoo, So Yeon Yoo, Jong Seob Lee, Ji Hoon Ahn (2005) CONSTANS activates SUPPRESSOR OF OVEREXPRESSION OF CO 1 through FLOWERING LOCUS T. Plant Physiology 139 (2), 770-778 (Oct 2005)

    * THIS PAPER RANKS AMONG THE TOP 40 HIGHLY CITED PAPERS OF 2005 PUBLISHED IN PLANT PHYSIOLOGY *
    Dong-Keun Lee*, Ji Hoon Ahn*, Sang-Kee Song, Yang Do Choi, and Jong Seob Lee (2003) Expression of an Expansin Gene Is Correlated with Root Elongation in Soybean. Plant Physiology 131 (3), 985-997 (Mar 2003)
    Miguel. A. Blazquez *, Ji Hoon Ahn *, and Detlef Weigel (2003) A thermosensory pathway controlling flowering time in Arabidopsis. Nature Genetics. 33(2), 168-171. * co-first author (Feb 2003)

    * THIS PAPER RANKS AMONG THE TOP 110 HIGHLY CITED PAPERS OF 2003 PUBLISHED IN NATURE GENETICS *
    Detlef Weigel, Ji Hoon Ahn, Miguel A Blázquez, Justin O Borevitz, Sioux K Christensen, Christian Fankhauser, Cristina J., Ferrandiz, C., Kardailsky, I., Malancharuvil, EJ, Neff, MM, Nguyen, JT, Sato, K., Weigel, JH, Blazquez, MA, Borevitz, JO, Christensen, S., Wang, ZY, Xia, Y., Dixon, RA, Harrison, MJ, Lamb, CJ, Yanofsky, MF, and Chory, J. (2000). Activation tagging in Arabidopsis. Plant Physiology 122, 1003-1013.

    * THIS PAPER RANKS THE TOP 1 HIGHLY CITED PAPER OF 2000 PUBLISHED IN PLANT PHYSIOLOGY *
    K., K., K., Shukla, VK, Ahn, JH, Dagenais, N., Christensen, SK, Nguyen, JT, Chory, J., Harrison, MJ, and Weigel, D. (1999) Activation tagging of the floral inducer FT. Science 286, 1962-1965. * co-first author

    * THIS PAPER RANKS THE TOP 7 HIGHLY CITED PAPER PUBLISHED IN ALL-TIME FLOWERING TIME RESEARCHES *
    Ahn, JH, Choi, Y., Kim, SG, Kwon, YM, Choi, YD, and Lee, JS (1998). Expression of a Soybean Hydroxyproline-Rich Glycoprotein Gene Is Correlated with Maturation of Roots. Plant Physiology 116, 671-679.
    Ahn, JH, Choi, Y., Kwon, YM, Kim, SG, Choi, YD, and Lee, JS (1996). A novel extensin gene encoding a hydroxyproline-rich glycoprotein requires sucrose for its wound-inducible expression in transgenic plants. Plant Cell 8 , 1477-1490.

    * The very first Plant Cell paper published in Korea

     

    All publications
    All Publications
    88

    Gawarecka, Katarzyna, and Ji Hoon Ahn. "RuBisCO Depletion and Subcellular Fractionation for Enhanced Florigen Detection in Arabidopsis." Thermomorphogenesis: Methods and Protocols (pp. 227-238) New York, NY: Springer US, 2024. 

    https://link.springer.com/protocol/10.1007/978-1-0716-3814-9_21

    87

    Suhyun Jin†, Geummin Youn†, Sun Young Kim, Taewook Kang, Hyun-young Shin, Ji-Yul Jung, Pil Joon Seo, and Ji Hoon Ahn (2024) The CUL3A–LFH1–UBC15 ubiquitin ligase complex mediates SHORT VEGETATIVE PHASE degradation to accelerate flowering at high ambient temperature. Plant Communications. https://doi.org/10.1016/j.xplc.2024.100814

    86
    Hendry Susila†, Zeeshan Nasim† , Katarzyna Gawarecka, Ji-Yul Jung, Suhyun Jin, Geummin Youn, and Ji Hoon Ahn (2023) Chloroplasts prevent precocious flowering through a GOLDEN2-LIKE–B-BOX DOMAIN PROTEIN module. Plant Communications. https://doi.org/10.1016/j.xplc.2023.100515
    85 Suhyun Jin, Sun Young Kim, Hendry Susila, Zeeshan Nasim, Geummin Youn, Ji Hoon Ahn (2022). FLOWERING LOCUS M isoforms differentially affect the subcellular localization and stability of SHORT VEGETATIVE PHASE to regulate temperature-responsive flowering in Arabidopsis. Molecular Plant . 15(11), 1696-1709

     

    This paper has been covered by Spotlight article ( https://www.cell.com/molecular-plant/fulltext/S1674-2052(22)00354-9 )

    84 Hendry Susila, Snježana Juric´, Katarzyna Gawarecka, Kyung Sook Chung, Suhyun Jin, Soo-Jin Kim, Zeeshan Nasim, Geummin Youn, Ji Hoon Ahn (2021) In vitro Assays to Evaluate Specificity and Affinity in Protein-phospholipid Interactions. Bio-protocol . 12(10). doi: 10.21769/BioProtoc.4421
    83 Zeeshan Nasim, Hendry Susila, Suhyun Jin, Geummin Youn, Ji Hoon Ahn (2022) PAF1C-regulated FLOWERING LOCUS C-clade genes repress flowering in response to chilling. Frontiers in Plant Science . 13:817356. doi: 10.3389/fpls.2022.817356.
    82 Katarzyna Gawarecka, Siwinska Joanna, Poznanski Jaroslaw, Onysk Agnieszka, Surowiecki Przemyslaw, Sztompka Karolina, Surmacz Liliana, Ahn Ji Hoon, Korte Arthur, Swiezewska Ewa, Ihnatowicz Anna (2021) cis-Prenyltransferase 3 and α/β-hydrolase are new determinants of Dolichol accumulation in Arabidopsis. Plant Cell & Environment . https://doi.org/10.1111/pce.14223

    81

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    Katarzyna Gawarecka and Ji Hoon Ahn (2021) Isoprenoid-derived metabolites and sugars in the regulation of flowering time: Does day length matter? Frontiers in Plant Science . 12:765995. doi: 10.3389/fpls.2021.765995
    80

    Hendry Susila, Snježana Juric´, Lu Liu, Katarzyna Gawarecka, Kyung Sook Chung, Suhyun Jin, Soo-Jin Kim, Zeeshan Nasim, Geummin Youn, Mi Chung Suh, Hao Yu, Ji Hoon Ahn (2021). Florigen sequestration in cellular membranes modulates temperature-responsive flowering. ScienceDOI: 10.1126/science.abh4054. Paper link

    *This paper featured in Science perspective

    https://www.science.org/doi/10.1126/science.abl4883
    79 Zeeshan Nasim, Muhammad Fahim, Hocheol Hwang, Hendry Susila, Suhyun Jin, Geummin Youn, Ji Hoon Ahn (2021). Nonsense-mediated mRNA decay modulates Arabidopsis flowering time via the SET DOMAIN GROUP 40–FLOWERING LOCUS C module. Journal of Experimental Botany . https://doi.org/10.1093/jxb/erab331 .
    78 Hendry Susila, Zeeshan Nasim, Suhyun Jin, Geummin Youn, Hyewon Jeong, Ji-Yul Jung and Ji Hoon Ahn (2021). Profiling Protein–DNA Interactions by Chromatin Immunoprecipitation in Arabidopsis. In: Posch A. (eds) Proteomic Profiling. Methods in Molecular Biology , vol 2261. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1186-9_21

    77

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    Suhyun Jin and Ji Hoon Ahn (2021). Regulation of Flowering Time by Ambient Temperature: Repressing the Repressors and Activating the Activators.  New Phytologist . 230 (3), 938-942
    76 Katarzyna Gawarecka, Joanna Siwinska, Jaroslaw Poznanski, Agnieszka Onysk, Przemyslaw Surowiecki, Liliana Surmacz, Ji Hoon Ahn, Arthur Korte, Ewa Swiezewska, Anna Ihnatowicz (2020). GWAS analysis combined with QTL mapping identify CPT3 and ABH as genes underlying dolichol accumulation in Arabidopsis. bioRxiv preprint. doi: https://doi.org/10.1101/2020.10.21.348912

    75

    20-1 Journal

    K2001561

    Hendry Susila, Zeeshan Nasim, Katarzyna Gawarecka, Ji-Yul Jung, Suhyun Jin, Geummin Youn, and Ji Hoon Ahn (2020). PHOSPHORYLETHANOLAMINE CYTIDYLYLTRANSFERASE 1 modulates flowering in a florigen-independent manner by regulating SVP. Development .

    .

    This paper has been selected as a "Research Highlight" of the issue.

    73

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    Suhyun Jin, Zeeshan Nasim, Hendry Susila, and Ji Hoon Ahn (2021). Evolution and functional diversification of  FLOWERING LOCUS T/TERMINAL FLOWER 1  family genes in plants. Seminars in Cell and Developmental Biology . 109, 20-30

    74

    19-2 academic journal

    K1821581

    Zeeshan Nasim, Muhammad Fahim, Katarzyna Gawarecka, Hendry Susila, Suhyun Jin, Youn Geummin and and Ji Hoon Ahn (2020). Role of AT1G72910 , AT1G72940 , and ADR1-LIKE 2 in Plant Immunity under Nonsense-Mediated mRNA Decay-Compromised Conditionsat Low Temperatures. International Journal of Molecular Sciences . 21:7986. doi: 10.3390/ijms21217986

    72

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    Lee Chung-Hee, Kim Soo-Jin, Jin Suhyun, Susila Hendry, Youn Geummin, Nasim Zeeshan, Alavilli Hemasundar, Chung Kyung Sook, Yoo Seong Jeon and Ahn, Ji Hoon (2019). Genetic interactions reveal the antagonistic roles of FT/TSF and TFL1 in the determination of inflorescence meristem identity in Arabidopsis. The Plant Journal . 99(3) 452-464

    71

    18-2 academic journal

    K1818181

    Keumbi Hwang, Hendry Susila, Zeeshan Nasim, Ji-Yul Jung and Ji Hoon Ahn (2019). Arabidopsis ABF3 and ABF4 transcription factors act with the NF-YC complex to regulate SOC1 expression and mediate drought-accelerated Flowering. Molecular Plant . ​12(4) 489-505   https://doi.org/10.1016/j.molp.2019.01.002

    * This paper was selected as Editor's choice (2019)

    https://www.cell.com/molecular-plant/libraries/editors-choice

    70 Ji-Yul Jung, Ji Hoon Ahn and Daniel P. Schachtman (2018). CC-type glutaredoxins mediate plant response and signaling under nitrate starvation in Arabidopsis. BMC Plant Biology . 18:281. doi:  10.1186/s12870-018-1512-1 .

    69

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    Hendry Susila, Zeeshan Nasim and Ahn Ji Hoon (2018). Ambient Temperature-Responsive Mechanisms Coordinate Regulation of Flowering Time. International Journal of Molecular Sciences . 19(10):3196. doi: 10.3390/ijms19103196.
    68
    17-1
    Paper K1701331
    Phanu Serivichyaswat, Hendry Susila and Ji Hoon Ahn (2017). ELONGATED HYPOCOTYL 5-HOMOLOG (HYH) negatively regulates Expression of the Ambient Temperature-Responsive MicroRNA Gene MIR169. Frontiers in Plant Science. 8:2087.

    67

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    Suhyun Jin, Sun Young Kim and Ji Hoon Ahn (2017). TWIN SISTER OF FT (TSF) Interacts with FRUCTOKINASE6 and Inhibits its Kinase Activity in Arabidopsis. Frontiers in Plant Science 8:1807.
    66 Jeong Hwan Lee, Suhyun Jin, Sun Young Kim, Wanhui Kim and Ji Hoon Ahn (2017). A fast, efficient chromatin immunoprecipitation method for studying protein-DNA binding in Arabidopsis mesophyll protoplasts. Plant Methods 13(1), 42
    65 Hee-Eun Kim, Wanhui Kim, Ae-Ree Lee, Suhyun Jinb, A Rim Jun, Nak-Kyoon Kim, Joon-Hwa Lee and Ji Hoon Ahn (2017). Base-pair opening dynamics of the microRNA precursor pri-miR156a affect temperature-responsive flowering in Arabidopsis. Biochemical and Biophysical Research Communications 484 (4), 839-844.
    64 Ji Hoon Ahn and Markus Schmid (2017) Editorial overview: Growth and development: Change in the air: how plants modulate development in the environment. Current Opinion in Plant Biology 35: iv-vi
    63 Wanhui Kim, Hee-Eun Kim, Ae-Ree Lee, A Rim Jun, Myeong Gyo Jung, Ji Hoon Ahn and Joon-Hwa Lee (2017) Base-pair opening dynamics of primary miR156a using NMR elucidates structural determinants important for its processing level and Leaf Number Phenotype in Arabidopsis. Nucleic Acids Research 45 (2): 875-885
    62 Zeeshan Nasim, Muhammad Fahim, and Ji Hoon Ahn (2017) Possible role of MADS AFFECTING FLOWERING 3 and B-BOX DOMAIN PROTEIN 19 in flowering time regulation of Arabidopsis mutants with defects in nonsense-mediated mRNA decay. Frontiers in Plant Science 8: article 191
    61 Hendry Susila, Suhyun Jin, and Ji Hoon Ahn (2016) Light Intensity and Floral Transition: Chloroplast Says "Time to Flower!" Molecular Plant 9 (12), 1551-1553
    60 Wanhui Kim, A Rim Jun, and Ji Hoon Ahn (2016) Proximal disruption of base pairing of the second stem in pri-miR156a by ambient temperature-sensitive flowering in Arabidopsis. Plant Signaling & Behavior 11 (10), e1226455
    59
    16-1
    Paper K1602221
    Wanhui Kim, Hee-Eun Kim, A Rim Jun, Myeong Gyo Jung, Suhyun Jin, Joon-Hwa Lee and Ji Hoon Ahn (2016) Structural determinants of miR156a precursor processing in temperature-responsive flowering in Arabidopsis Journal of Experimental Botany 67 (15) ): 4659-4670
    58 Ji Hoon Ahn (2016) Flowering time: Have florigen, will travel. Nature Plants 2 (6): 16081 (June 3, 2016)
    57
    15-2
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    Soo-Jin Kim, Sung Myun Hong, Seong Jeon Yoo, Suhyun Moon, Hye Seung Jung and Ji Hoon Ahn (2016) Post-Translational Regulation of FLOWERING LOCUS T Protein in Arabidopsis. Molecular Plant 9 (2): 308-311 (February 1, 2016)
    56 Esther Marín-González, Luis Matías-Hernández, Andrea E. Aguilar-Jaramillo, Jeong Hwan Lee, Ji Hoon Ahn, Paula Suárez-López and Soraya Pelaz (2015) SHORT VEGETATIVE PHASE specifically activates TEMPRANILLO2 floral repressor at low ambient temperatures. Plant Physiology 169 (2): 1214-1224 (October 1, 2015)
    55 Suhyun Jin Hye Seung Jung Kyung Sook Chung Jeong Hwan Lee Ji Hoon Ahn (2015) FLOWERING LOCUS T (FT) has higher protein mobility than TWIN SISTER OF FT (TSF). Journal of Experimental Botany 66 (20): 6109-6117 (October 1, 2015)
    54
    14-2
    K1426181
    Phanu Serivichyaswat, Hak-Seung Ryu, Wanhui Kim, Sonkap Kim, Kyung Sook Chung, Jae Joon Kim, and Ji Hoon Ahn (2015) Expression of the Floral Repressor miRNA156 is Positively Regulated by the AGAMOUS-like Proteins AGL15 and AGL18. Molecules and Cells 38 (3), 259-266 (March 31, 2015)
    53
    13-2
    K1326992
    Wanhui Kim and Ji Hoon Ahn (2014) MicroRNA-target interactions: important signaling modules regulating flowering time in diverse plant species. Critical Reviews in Plant Sciences 33 (6): 470-485 (November 2, 2014)
    52 Huang-Lung Tsai, Yi-Hang Li, Wen-Ping Hsieh, Meng-Chun Lin, Ji Hoon Ahn and Shu-Hsing Wu (2014) HUA ENHANCER1 Is Involved in Posttranscriptional Regulation of Arabidopsis Photomogenesis. Plant Cell 26 (7) 2858-2872. (July 1, 2014)
    51 Jeong Hwan Lee, Kyung Sook Chung, Soonkap Kim, and Ji Hoon Ahn (2014) Post-translational regulation of SHORT VEGETATIVE PHASE as a major mechanism for thermoregulation of flowering. Plant Signaling & Behavior 9 (2): e28193 (April 1, 2014)
    50 Jae Yong Ryu, Hyo-Jun Lee, Pil Joon Seo, Jae-Hoon Jung, Ji Hoon Ahn, and Chung-Mo Park (2014) The Arabidopsis Floral Repressor BFT Delays Flowing by Competing with FT for Binding under High Salinity. Molecular Plant 7 (2) 377-387 (February 1, 2014)
    49 Jeong Hwan Lee, Hak-Seung Ryu, Kyung Sook Chung, David Posé, Sonkap Kim, Markus Schmid, and Ji Hoon Ahn (2013) Regulation of Temperature-Responsive Flowering by MADS-Box Transcription Factor Repressors. Science 342 (6158): 628-632 (November 1, 2013)
    Abstract    Reprint
    * Featured in a Science Perspective Click Here
    * Editor's Choice in Science Signaling Click Here
    48 Kyung Sook Chung, Jeong Hwan Lee, Jong Seob Lee, and Ji Hoon Ahn (2013) Fruit indehiscence caused by enhanced expression of NO TRANSMITTING TRACT in Arabidopsis thaliana. Mol. Cells 35 (6) 519-525 (June 2013)
    47 Wanhui Kim, Tae Im Park, Seong Jeon Yoo, A Rim Jun, and Ji Hoon Ahn (2013) Generation and analysis of a complete mutant set for the Arabidopsis FT/TFL1 family of thermo-sensitive flowering regulation. Journal of Experimental Botany 64 (6): 1715-1729. (April, 2013)
    46 Seong Jeon Yoo, Sung Myun Hong, Hye Seung Jung, and Ji Hoon Ahn * (2013) The Cotyledons Produce Sufficient FT Protein to Induce Flowering: Evidence from Cotyledon Micrografting in Arabidopsis. Plant and Cell Physiology 54(1): 119-128 (January, 2013)
    * Selected as an "Editor-in-Chief's Choice of the January Issue
    45 Jeong Hwan Lee Jae Joon Kim Soo Hyun Kim Hyun Jung Cho Joonki Kim and Ji Hoon Ahn (2011) The E3 ubiquitin ligase HOS1 Regulates Low Ambient Temperature-Responsive Flowering in Arabidopsis thaliana Plant and Cell Physiology 53 (10): 1802-1814 (October , 2012)
    44 Jeong Hwan Lee, Jae Joon Kim, and Ji Hoon Ahn (2012) Role of SEPALLATA3 (SEP3) as a downstream gene of miR156-SPL3-FT circuitry in ambient temperature-responsive flowering. Plant Signaling & Behavior 7 (9): 1151-1154 (September, 2012)
    43 Jeong Hwan Lee, Soo Hyun Kim, Jae Joon Kim, and Ji Hoon Ahn (2012) Alternative Splicing and Expression Analysis of Arabidopsis in Hormone-Resistant Genes 1 (HOS1). BMB Reports 45 (9): 515-520 (September 30, 2012)
    42 Hyun Jung Cho, Jae Joon Kim, Jeong Hwan Lee, Wanhui Kim, Jae-Hoon Jung, Chung-Mo Park and Ji Hoon Ahn (2012) SHORT VEGETATIVE PHASE (SVP) protein negatively regulates miR172 transcription via direct binding to the pri-miR172a promoter in Arabidopsis. FEBS Letters. 586 (16): 2332-2337 (July 30, 2012)
    41 Hyunmin Roh, Cheol Woong Jeong, S Fujioka, Yoon Kyung Kim, S Lee, Ji Hoon Ahn, Yang Do Choi, and Jong Seob Lee (2012) Genetic Evidence for Brassinosteroid Levels by a BAHD Acyltransferase-Like Protein in Arabidopsis. Plant Physiology 159 (2): 696-709 (June, 2012)
    40 Jae Hoon Jung, Pil Joon Seo, Ji Hoon Ahn, and Chung Mo Park (2012) The Arabidopsis RNA-binding protein FCA regulates microRNA172 processing in thermosensory flowering. J. of Biological Chemistry 287 (19): 16007-16016 (May 4, 2012)
    39 Jae Joon Kim, Jeong Hwan Lee, Wanhui Kim, Hye Seung Jun, Peter Huijser, and Ji Hoon Ahn (2012) The microRNA156-SQUAMOSA PROMOTER BINDING PROTEIN-LIKE3 Module Regulates Ambient Temperature-Responsive Flowering via FLOWERING LOCUS T in Arabidopsis. Plant Physiology 159 (1): 461-78 (May, 2012)
    38 Jeong Hwan Lee, Soo Hyun Park, and Ji Hoon Ahn (2012) Functional conservation and diversification between rice OsMADS22 / OsMADS55 and Arabidopsis SVP proteins. Plant Science 185-186 97-104 (April, 2012)
    37 Wanhui Kim, Hae Ji Ahn, Tzyy-Jen Chiou, Ji Hoon Ahn (2011) The role of the miR399-PHO2 module in the regulation of flowering time in response to different ambient temperatures in Arabidopsis thaliana. Mol Cells 32 (1) 83-88 (July 01, 2011)
    * THIS PAPER RANKS AMONG THE TOP 5% HIGHLY CITED PAPERS OF 2011 PUBLISHED PUBLISHED IN Mol Cells *
    36 Seung Kwan Yoo, Sung Myun Hong, Jong Seob Lee, Ji Hoon Ahn (2011) A genetic screen for leaf movement mutants identifies a potential role for AGAMOUS-LIKE 6 (AGL6) in circadian-clock control. Mol Cells 31(3), 281-287 (March 01, 2011)
    35 Seong Kwan Yoo, Xuelin Wu, Jong Seob Lee, Ji Hoon Ahn (2011) AGAMOUS-LIKE 6 is a floral promoter that negatively regulates the FLC/MAF clade genes and positively regulates FT in Arabidopsis. Plant Journal 65 (1), 62-76 (January 01, 2011)
    34 Sung Myung Hong, Sung Chul Bahn, Aram Lyu, Hye Seung Jung, Ji Hoon Ahn (2010) Identification and testing of superior reference genes for a transcript normalization in Arabidopsis. Plant and Cell Physiology 51 (10), 694-706 (October 01, 2010)
    33 BROTHER OF FT AND TFL1 (BFT), a member of the FT / TFL1 family, shows distinctive patterns of expression during the vegetative growth. Arabidopsis. Plant Signaling and Behavior 5 (9), 1102-1104 (September 09, 2010)
    32 Seong Jeon Yoo, Kyung Sook Chung, Seung Hye Jung, So Yeon Yoo, Jong Seob Lee, Ji Hoon Ahn (2010) BROTHER OF FT (BFT) has TFL1-like activities and functions redundantly with TFL1 in inflorescence meristem development in Arabidopsis. Plant Journal 63 (2), 241-53 (July 01, 2010)
    31 Hanna Lee, Seong Jeon Yoo, Jeong Hwan Lee, Wanhui Kim, Seung Kwan Yoo, Heather Fitzgerald, James C Carrington, Ji Hoon Ahn (2010) Genetic framework for flowering-time regulation by ambient temperature-responsive miRNAs in Arabidopsis. Nucleic Acids Research 38 (9), 3081-3093 (May 01, 2010)
    * THIS PAPER RANKS AMONG THE TOP 10% HIGHLY CITED PAPERS OF 2010 PUBLISHED PUBLISHED IN NUCLEIC ACIDS RESEARCH *
    30
    CFG50
    SIG50
    Edward Allen, Ji Hoon Ahn, and James C. Carrington (2008) Inaugural Article (2008) Inaugural Article (2008) Inaugural Article : AGO1-miR173 complex initiates phased siRNA formation in plants. PNAS 105 (51), 20055-20061 (December 22, 2008)
    * THIS PAPER RANKS AMONG THE TOP 25% HIGHLY CITED PAPERS OF 2008 PUBLISHED IN PNAS *
    29
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    SIG30
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    Jeong Hwan Lee, Jong Seob Lee, and Ji Hoon Ahn (2008) Ambient temperature signaling in plants: an emerging field in the regulation of flowering time. Journal of Plant Biology 51 (5): 321-326
    28
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    SIG30
    So Yeon Yoo, Yunhee Kim, Soo Young Kim, Jong Seob Lee, and Ji Hoon Ahn (2007) Control of flowering time and cold response by a NAC-domain protein in Arabidopsis. PLoS ONE 2 (7), e642 (July 25, 2007)
    * THIS PAPER IS SELECTED AS A HIGHLY VIEWED ARTICLE (> 2,000 VIEWS / YEAR)
    27
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    BCC40
    Jeong Hwan Lee, Soo Hyun Park, Jong Seob Lee, and Ji Hoon Ahn (2007) A conserved role of SHORT VEGETATIVE PHASE (SVP) in controlling flowering time of Brassica plants. Biochimica et Biophysica Acta - Gene Structure and Expression 1769 (7-8): 455-461 (July 2007)
    26 Soo-Yun Kim, Beom-Seok Park, Soo-Jin Kwon, Jungsun Kim, Young-Doo Park, Dool Yi Kim, Seok-Chul Suh, Yong-Moon Jin, Ji Hoon Ahn, and Yeon-Hee Lee (2007) Delayed flowering time in Arabidopsis and Brassica rapa by overexpression of FLOWERING LOCUS C (FLC) homologs isolated from Chinese cabbage (Brassica rapa L. ssp. Plant Cell Reports 26 (3): 327-336 (Mar 2007)
    25
    CFG60
    SIG30
    BCC10
    Jeong Hwan Lee, Seong Jeon Yoo, Soo Hyun Park, Ildoo Hwang, Jong Seob Lee, and Ji Hoon Ahn (2007) Role of SVP in the control of flowering time by ambient temperature in Arabidopsis. Genes and Development 21 (4), 397-402
    * THIS PAPER RANKS AMONG THE TOP 20% HIGHLY CITED PAPERS OF 2007 PUBLISHED IN GENES & DEVELOPMENT *
    24
    CFG100
    Ji Hoon Ahn, Joonki Kim, Seong Jeon Yoo, So Yeon Yoo, Hyungmin Roh, Jun Hyuk Choi, Mi Suk Choi, Kyung Sook Chung, Eun Ju Han, Sung Myun Hong, (2007) Isolation of 151 mutants that have been reported to be involved in the pathogenesis of schizophrenia. developmental defects from T-DNA tagging. Plant and Cell Physiology 48 (1), 169-178 (Jan 2007)
    23
    CFG60
    SIG30
    KRF10
    Seong Kwan Yoo, Jong Seob Lee, and Ji Hoon Ahn (2006) Overexpression of AGAMOUS-LIKE 28 (AGL28) promotes flowering by upregulating expression of floral promoters within the autonomous pathway. Biochemical and Biophysical Research Communications 348: 929-936 (July 2006)
    22 Sun Jae Kwon, Eun Young Cho, Eun Joung Choi, Ji Hoon Ahn, Ohkmae K. Park (2006) Proteomic studies of post-translational modifications in plants. J. Experimental Botany 57: 1547-1551 (Apr 2006)
    21
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    SIG50
    Jeong Hwan Lee, Sung Myun Hong, Seong Jeon Yoo, Ohkmae K. Park, Jong Seob Lee and Ji Hoon Ahn (2006) Integration of floral inductive signals by FLOWERING LOCUS T (FT) and SUPPRESSOR OF OVEREXPRESSION OF CO 1 (SOC1). Physiologia Plantarum 126 (4): 475-483 (Apr 2006)
    20
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    SIG20
    MAX50
    Ji Hoon Ahn †, David J. Miller, Victoria J. Winter, Mark J. Banfield, Jeong Hwan Lee, So Yeon Yoo, Stefan R. Henz, R. Leo Brady, and Detlef Weigel * (2006) A divergent external loop confers antagonistic activity on floral regulators FT and TFL1. EMBO J. 25: 605-614 (Feb 2006) † co-first author
    * THIS PAPER RANKS AMONG THE TOP 40 HIGHLY CITED PAPERS OF 2006 PUBLISHED IN EMBO JOURNAL
    19
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    KRF20
    Seung Kwan Yoo, Kyung Sook Chung, Joonki Kim, Jeong Hwan Lee, Sung Myun Hong, Seong Jeon Yoo, So Yeon Yoo, Jong Seob Lee, Ji Hoon Ahn (2005) CONSTANS activates SUPPRESSOR OF OVEREXPRESSION OF CO 1 through FLOWERING LOCUS T. Plant Physiology 139 (2), 770-778 (Oct 2005)

    * THIS PAPER RANKS AMONG THE TOP 40 HIGHLY CITED PAPERS OF 2005 PUBLISHED IN PLANT PHYSIOLOGY *
    18
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    SIG30
    So Yeon Yoo, Kirsten Bomblies, Seung Kwan Yoo, Jung Won Yang, Mi Suk Choi, Jong Seob Lee, Detlef Weigel and Ji Hoon Ahn (2005) The 35S promoter was used as a selectable marker gene for a plant transformation vector affects the expression of the transgene. Planta 221: 523-530 (June 2005)

    * THIS PAPER RANKS AMONG THE TOP 70 HIGHLY CITED PAPERS OF 2005 PUBLISHED IN PLANTA *
    17 Ban Yoon Cheon, Hae Jin Kim, Kyung Hee Oh, Sung Chul Bahn, Ji Hoon Ahn, Jang Won Choi, Sung Han Ok, Jung Myung Bae and Jeong Sheop Shin (2004) Overexpression of human erythropoietin (EPO) affects plant morphologies: retarded vegetative growth in tobacco and male sterility in tobacco and Arabidopsis. Transgenic Research 13 (6), 541-549 (Dec 2004)
    16 So Yeon Yoo, Igor Kardailsky, Jong Seob Lee, Detlef Weigel, and Ji Hoon Ahn (2004) Acceleration of flowering by overexpression of MFT (MOTHER OF FT AND TFL1). Molecules and Cells. 17 (1), 95-101 (Feb 2004)

    * THIS PAPER RANKS AMONG THE TOP 7 HIGHLY CITED RESEARCH PAPERS OF 2004 PUBLISHED IN MOLECULES AND CELLS *
    15 Ji Hoon Ahn and Jong Seob Lee (2003) Sugar acts as a regulatory signal on the wound-inducible expression of SbHRGP3 :: GUS in transgenic plants. Plant Cell Reports 22 (4), 286-293. (Nov 2003)
    14 Dong-Keun Lee *, Ji Hoon Ahn *, Sang-Kee Song, Yang Do Choi, and Jong Seob Lee (2003) Expression of an Expansin Gene Is Correlated with Root Elongation in Soybean. Plant Physiology 131, 985-997 * co-first author (Mar 2003)
    13 Miguel. A. Blazquez *, Ji Hoon Ahn *, and Detlef Weigel (2003) A thermosensory pathway controlling flowering time in Arabidopsis. Nature Genetics 33 (2), 168-171. * co-first author (Feb 2003)

    * THIS PAPER RANKS AMONG THE TOP 110 HIGHLY CITED PAPERS OF 2003 PUBLISHED IN NATURE GENETICS
    12 Sang Ik Song, Jin Nam Choi, Jong Tae Song, Ji Hoon Ahn, Jong Seob Lee, Minkyun Kim, Jong-Joo Cheong, and Yang Do Choi (2002). Complete genome sequence of garlic latent virus, a member of the carlavirous family. Molecules and Cells. 14 (2), 205-213. (Oct 31, 2002)
    11 Murata, M., Motoyoshi, F., and Sakamoto, W. (2001). Functional divergence of the TFL1-like gene family in Arabidopsis revealed by a novel member, ATC. Genes to Cells. 6 (4), 327-336. [PDF] (April, 2001)
    10 Lee, Sung - Suk Suh, Eunsook Park, Euna Cho, Ji Hoon Ahn, Sang - Gu Kim, Jong Seob Lee, Young Myung Kwon, and Ilha Lee (2000). The AGAMOUS-LIKE 20 MADS domain protein integrates floral inductive pathways in Arabidopsis. Genes and Development 14, 2366-2376. [ PDF ]
    9 Detlef Weigel, Ji Hoon Ahn, Miguel A Blázquez, Justin O Borevitz, Sioux K Christensen, Christian Fankhauser, Cristina J., Ferrandiz, C., Kardailsky, I., Malancharuvil, EJ, Neff, MM, Nguyen, JT, Sato, K., Weigel, JH, Blazquez, MA, Borevitz, JO, Christensen, S., Wang, ZY, Xia, Y., Dixon, RA, Harrison, MJ, Lamb, CJ, Yanofsky, MF, and Chory, J. (2000). Activation tagging in Arabidopsis. Plant Physiology 122, 1003-1013. [PDF]

    * THIS PAPER RANKS THE TOP 1 HIGHLY CITED PAPER OF 2000 PUBLISHED IN PLANT PHYSIOLOGY *
    8 Kardailsky, I. *, Shukla, VK *, Ahn, J. H *., Dagenais, N., Christensen, SK, Nguyen, JT, Chory, J., Harrison, MJ, and Weigel, D. (1999). Activation tagging of the floral inducer FT. Science 286, 1962-1965. * co-first author [ PDF ]

    * THIS PAPER RANKS THE TOP 7 HIGHLY CITED PAPER PUBLISHED IN ALL-TIME FLOWERING TIME RESEARCHES *
    7 Ahn, JH, Choi, Y., Kim, SG, Kwon, YM, Choi, YD, and Lee, JS (1998). Expression of a Soybean Hydroxyproline-Rich Glycoprotein Gene Is Correlated with Maturation of Roots. Plant Physiology 116, 671-679. [PDF]
    6 Jeong, SH, Ahn, JH, Lee, JS, and Lee, JS (1997). Molecular characterization of a protein kinase gene in Chinese cabbage (Brassica campestris subsp. Napus var. Korean J. Biological Sciences 1 , 135-142. (March 1997)
    5 Ahn, JH, Choi, Y., Kwon, YM, Kim, SG, Choi, YD, and Lee, JS (1996). A novel extensin gene encoding a hydroxyproline-rich glycoprotein requires sucrose for its wound-inducible expression in transgenic plants. Plant Cell 8,1477-1490.
    4 Song, JT, Ahn, JH, Lee, JS, and Choi, YD (1996). The loop B domain is physically separable from the loop domain in the hairpin ribozyme. Nucleic Acids Research 24, 2685-2689. [PDF]
    3 Song, JT, Ahn, JH, Lee, JS, and Choi, YD (1996). Site-specific cleavage of RNA with a latent virus coat protein by a hairpin type ribozyme. Molecules and Cells 6, 209-214. (April 1996)
    2 Song, SI, Choi, JN, Song, JT, Ahn, JH, Lee, JS, and Choi, YD (1995). Immunological detection of garlic latent virus. J. Kor. Agri. Chem 38, 49-54.
    1 Choi, Y., Ahn, JH, Choi, YD, and Lee, JS (1995). Tissue-specific and developmental regulation of a gene encoding a low molecular weight sulfur-rich protein in soybean seeds. Mol Gen Genet 246, 266-268.


    특허

     

    국제 특허

    1.      Method for controlling flowering time by regulating of SVP-FLM-.beta. protein complex formation. US patent 등록번호/일자 10,717,984 (2020.07.21)

    2.     Gene controlling flowering time of plants and method for manipulating flowering time of plant using the same. US patent 등록번호/일자 7,230,164 (2007. 06.12)

    3.     Root-specific expansin gene regulating root growth and obstacle-touching stress resistance in the plant. US patent 등록번호/일자 7,217,861 (2007.05.15)

     

    국내 특허

    1.      SVP-FLM-β 단백질 복합체의 형성 조절을 통한 식물의 개화시기 조절 방법(Method for Controlling Flowering Time by Regulating of SVP-FLM-beta Protein Complex Formation) 출원번호/일자 1020140121375 (2014.09.12), 등록번호/일자 1016644510000 (2016.10.04)

    2.     애기장대 유래 유전자를 이용한 식물체의 크기 조절 방법 (Method of regulating plant size using Arabidopsis gene) 출원번호/일자 1020110019296 (2011.03.04), 등록번호/일자 1012612780000 (2013.04.30)

    3.     식물체의 크기 조절 방법 및 그에 따른 식물체 (Regulation method of plant size and the plant thereof), 출원번호/일자 1020080124355 (2008.12.09), 등록번호/일자 1010972110000 (2011.12.15)

    4.     개화시기에 관여하는 조절 유전자 SVP (SVP gene controlling flowering time), 출원번호/일자 1020070012375 (2007.02.06), 등록번호/일자 1008334730000 (2008.05.23)

    5. Method for controlling flowering time of plant using ECL1 gene, application number/date 1020060071233 (2006.07.28), registration number/date 1006477930000 (2006.11.13)

    6. Method for promoting flowering time of plant using AGL28 gene Application No./Date 1020060071234 (2006.07.28), Registration No./Date 1006481460000 (2006.11.14)

    7. Gene controlling root development of plants and method for manipulating root development of plant using the same Application No./Date 1020030019069 (2003.03.27), Publication No./ Date 1020040084186 (2004.10.06)

    8. Gene controlling flowering time of plants and method for manipulating flowering time of plant using the same, Application No./Date 1020030010772 (2003.02.20), Publication No. /Date 1020040075252 (2004.08.27)


     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

  • Research

    Professor Ahn has made seminal contributions to understanding the control of flowering time in response to ambient temperature. Dr. Ahn’s best-known discoveries are: (1) FLOWERING LOCUS T (FT), the long-sought florigen, is sequestered in cellular membranes in response to temperature changes to modulate flowering time (Science, 2021); (2) SVP forms a repressor protein complex with FLOWERING LOCUS M-beta (FLM-ß) to regulate ambient temperature responses (Science, 2013); and (3) a small group of genes form a distinctive genetic pathway (the ambient temperature pathway) and act to mediate ambient temperature responses (Genes and Development, 2007). These findings provided some of the first clues to the molecular genetic mechanism of plant behavior in response to ambient temperature changes.

     

    Global temperature changes significantly affect ambient temperature and therefore may have major effects on plant development, including that of essential food crops. Although a great deal of progress has been made in our understanding of the regulation of plant development by low temperature, less is currently known about the molecular mechanisms underlying the responses of plants to changes in ambient temperature. His findings have provided a new explanation for the genetic mechanisms by which plants respond to ambient temperature changes. For example, he identified the ambient temperature pathway genes that control flowering time (Nature Genetics, 2003). He has shown that SVP acts within the thermosensory pathway and plays a role in ambient temperature response via direct binding to the cis-acting element of FT, an important floral integrator gene (Genes and Development, 2007).

     

    In addition, he has shown that small RNAs play an important regulatory role in ambient temperature signaling and that SVP links the thermosensory pathway and ambient temperature-responsive miRNAs (Nucleic Acids Research, 2010). He has recently showed that the MADS-box proteins SVP and FLM-ß form a complex that mediates temperature responses in plants (Science, 2013). He also showed that control of the abundance of SVP–FLM-ß repressor complex at the transcriptional level (FLM-ß) and at the post-translational level (SVP) is important for plant responses to continuingly changing ambient temperatures. He also showed that ABF transcription factors work with NF-Y transcription factors to induce transcription of floral integrator genes under drought conditions, revealing the molecular mechanism underlying the drought-mediated acceleration of flowering (Molecular Plant, 2019). Recently, he also showed that FT molecules are sequestered in cellular membranes at low temperature due to their interaction with the membrane phospholipid phosphatidylglycerol, but are released from the membrane to transport to the sieve element to trigger flowering (Science, 2021). Therefore, Dr. Ahn’s impactful studies have shed light on the mechanisms involved in regulating flowering in response to ambient temperature, an important topic for basic plant biology and for agricultural applications.

     

    Selected publications

     

    1. Florigen sequestration in cellular membranes modulates temperature-responsive flowering. (2021) Science
    2. Regulation of temperature-responsive flowering by MADS-box transcription factor repressors. (2013) Science
    3. FLOWERING LOCUS M isoforms differentially affect the subcellular localization and stability of SHORT VEGETATIVE PHASE to regulate temperature-responsive flowering in Arabidopsis (2022) Molecular Plant
    4. Arabidopsis ABF3 and ABF4 transcription factors act with the NF-YC complex to regulate SOC1 expression and mediate drought-accelerated flowering. (2019) Molecular Plant
    5. A thermosensory pathway controlling flowering time in Arabidopsis. (2003) Nature Genetics
    6. Role of SVP in the control of flowering time by ambient temperature in Arabidopsis. (2007) Genes and Development
    7. Genetic framework for flowering-time regulation by ambient temperature-responsive miRNAs in Arabidopsis. (2010) Nucleic Acids Research

     

     

     

    우리 연구실은 주변 대기 온도 변화에 따른 생명체의 반응 (특히 개화시기 조절에 대한 기작)에 대한 연구를 하고 있다. 이 기작을 밝혀내기 위해 MADS box 단백질 복합체, small RNA, 개화호르몬의 작용기작을 중점으로 연구를 수행하고 있다.

     

    우리 연구실은 ‘고등식물의 개화 시기 조절’이라는 한 분야만을 25년 동안 연구하면서 ‘ambient temperature-responsive flowering’ 분야를 세계 최초로 개척하고 이 분야를 학계의 중심 연구 주제가 되도록 seminal contribution 했다. 해외 학계에서도 우리 연구실의 공헌을 높게 평가하고 있다. (The PI is a highly accomplished scientist who is consistently breaking new ground and pushing the frontiers of the Arabidopsis flowering field [해외 학자 #1]. He has pioneered the research of flowering in response to ambient temperature changes [해외 학자 #2]). 
     
    우리 연구실의 연구 수준은 세계적인 수준에 도달한 것으로 평가받고 있다. 2021년과 2013년에 발표한 두 편의 사이언스 논문을 포함하여 우리 연구실에서 발표한 80여 편의 논문은 10,000회가 넘는 피인용을 기록하고 있다. 해외 학계에서도 우리 연구실의 연구 업적의 수준에 대해서 높이 평가하고 있다. (The scientific quality of his achievements is excellent and his competence certainly equals that of top scientists in the plant field [해외 학자 #1]. The PI is an internationally renowned plant scientist with an outstanding track record in studying the flowering mechanisms [해외 학자 #2]. Dr. Ahn is one of the top researchers in the field of flowering control [해외 학자 #3]). 
     
    우리 연구실의 발견 중 가장 잘 알려진 것은 개화 유도 호르몬인 FT 단백질이 온도 변화에 반응하여 세포막에서 격리되어 개화 시기를 조절한다는 것이다 (Science, 2021). 우리는 이 논문을 통해 플로리겐이라고 불리는 FT 단백질이 온도 변화에 따라서 세포내에서 어떤 행동과 이동 경로를 보이는가를 밝혀냈다. 이 논문은 Faculty Opinions에서 Plant Science Landmark Paper로 심사 중에 있을 정도로 중요성을 띄는 논문이다. 또한 우리 연구실은 대기 온도 변화를 인지하는 신호 전달을 매개하는 단백질 복합체를 찾아내고 이 복합체가 온도계의 역할을 하여 대기 온도에 대한 반응성을 조절한다는 사실을 밝혀내기도 했다 (Science, 2013). 이러한 우리 연구실의 발견은 주변 온도 변화에 대해서 고등 식물체가 보이는 행동의 분자 유전 메커니즘을 이해하는데 필요한 중요한 단서를 제공하고 있다.
     
    최근 가속화되고 있는 지구 온난화에 의해 온도 변화가 식물 발달에 미치는 영향에 대한 우려가 증가하고 있다. 그동안의 연구를 통해 저온에 대응하여 일어나는 식물 발달의 조절에 대해서 많은 지식을 축적할 수 있었다. 그러나 대기 온도 변화에 대해서 식물체가 보이는 반응의 분자 메커니즘에 대해서는 알려진 바가 많지 않다. 우리 연구실의 발견은 고등식물체가 대기 온도 변화에 어떤 기작을 사용하여 반응하는지에 관해 새로운 설명을 제공하고 있다.
     

    우리 연구실이 대기 온도 반응성 개화에 대해서 학계에 미친 중요한 공헌을 시간 순서대로 요약하면 다음과 같다. 우리는 ambient temperature pathway에 작동하는 FCA, FVE 유전자들이 온도 변화에 반응하여 개화 시기를 조절한다는 것을 밝혀냈다 (Nature Genetics, 2003). 우리는 SHORT VEGETATIVE PHASE (SVP) 유전자가 이 ambient temperature pathway 내에서 작용하는 것을 규명했다. SVP 단백질은 중요한 floral integrator 유전자인 FLOWERING LOCUS T (FT) 유전자의 cis-acting element에 직접 결합하여 주변 온도 변화에 대한 반응을 매개하는 역할을 한다는 것을 보여주었다 (Genes and Development, 2007). 이 논문은 연 평균 40회가 넘는 피인용을 기록하고 있다. 또한 우리는 small RNA가 대기 온도 신호 전달에서 중요한 조절 역할을 하고 SVP가 ambient temperature pathway와 이 ​​온도 반응성 miRNA 사이의 연결을 제공한다는 것을 보여주었다 (Nucleic Acids Research, 2010). 우리는 MADS-box 단백질인 SVP와 FLOWERING LOCUS M이 온도 반응을 매개하는 복합체를 형성한다는 것을 보여주었다 (Science, 2013). 우리는 또한 전사 수준(FLM)과 번역 후 수준(SVP)에서 SVP-FLM 복합체의 양을 조절하는 ​기작이 존재하여 지속적으로 변화하는 주변 온도 조건에서 고등식물체가 생존하는데 이 온도계 단백질 복합체가 필요하다는 것을 보여주었다. 플로리겐 단백질에서 일어나는 post-translational modification에 대해서도 규명한 바 있다. (Molecular Plant, 2016). 우리는 ABF 전사 인자가 NF-Y 전사 인자와 함께 모듈을 형성하여 floral integrator 유전자의 전사를 조절함으로써 식물체의 개화를 조절한다는 것을 규명했다 (Molecular Plant, 2019). 이는 가뭄 상태에서 식물체의 개화가 빨라지는 현상에 관한 분자적 기작을 밝혀낸 것이다. 최근 우리는 FT 단백질이 저온에서는 인지질 분자인 포스파티딜글리세롤과의 상호작용으로 인해 세포막에 격리되지만, 온도가 높아지게 되면 세포막에서 방출되어 sieve element로 이동하여 개화를 유발한다는 것을 보여주었다 (Science, 2021).

     

    우리 연구실에서 학계에 보고한 연구 결과를 요약하면 다음과 같다.

     

    1. 우리는 대기 온도 경로에 관여하는 유전자가 개화시기를 조절한다는 것을 밝혀냈다 (Nature Genetics).
    2. 우리는 SVP 유전자가 온도 감지 경로 내에서 작용하고 있다는 사실을 보고했다. 또한 개화 호르몬인 FLOWERING LOCUS T (FT)의 cis-acting element에 직접 결합하여 대기 온도 반응에 역할을하는 것을 밝혀냈다 (Genes and Development).
    3. 우리는 small RNA가 주위 온도 신호 전달에서 중요한 조절 역할을 하며 SVP가 온도 감지 경로와 대기 온도 반응성 miRNA사이의 연결 고리를 제공한다는 것을 밝혀내었다 (Nucleic Acids Research).
    4. 우리는 최근 MADS-box 단백질 인 SHORT VEGETATIVE PHASE (SVP)와 FLOWERING LOCUS M-beta (FLM-beta)가 식물에서 온도 반응을 중재하는 복합체를 형성한다는 것을 밝혀냈다. 우리는 전사 수준 (FLM)과 번역 후 수준 (SVP)에서의 SVP-FLM- 베타 개화 억제자 복합체의 조절이 대기 온도 반응에 대한 식물의 반응에 중요하다는 것을 보여 주었다 (Science).
    5. 우리는 플로리겐 FT 단백질이 세포막에서 인지질의 일종인 PG와 결합하고 이 결합이 온도에 의해 조절됨으로써 대기 온도 반응성 개화를 조절한다는 것을 규명했다 (Science).

     

     

     

  • Invited Talks

         
    2023-11-02 Modulation of Temperature-Dependent Behavior of Floral Repressors by Protein Isoforms 2023 International Symposium on Plant Cell and Developmental Biology (Shanghai, China)
         
    2023-10-10
    Florigen and membrane phospholipids: How they regulate temperature-responsive flowering
    The 9th Asian-Oceanian Symposium on Plant Lipids (Seoul, Korea)
         
    2023-08-06 Modulation Of Temperature-Dependent Behavior Of Floral Repressors By Protein Isoforms
    The 15th INTERNATIONAL ASSOCIATION FOR PLANT BIOTECHNOLOGY CONGRESS (Daejon, Korea)
         
    2023-07-07 FLOWERING LOCUS M isoforms differentially affect the subcellular localization and stability of SHORT VEGETATIVE PHASE to regulate temperature-responsive flowering in Arabidopsis
    The 24th International Conference on Plant Growth Substances (Gyeongju, Korea)
         
    2023-02-23
    Lipid-mediated regulation of flowering time in Arabidopsis
    Rose Lecture 2023 KSMCB Winter Conference (Pyongchang, Korea)
         
    2022-08-09 Florigen and membrane phospholipids - the molecular jail in flowering
    The 14th INTERNATIONAL ASSOCIATION FOR PLANT BIOTECHNOLOGY CONGRESS (Daejon, Korea)
         
    2022-05-27 Regulation of flowering time by membrane phospholipid PG Seoul National University
         
    2021-11-11
    Florigen sequestration in cellular membranes – how it regulates temperature-responsive flowering
    Korean Society of Plant Biologists
         
    2021-10-29
    Florigen and membrane phospholipids - the molecular jail in flowering
    Seoul National University
         
    2019-11-03 Sequestration of florigen by membrane phosphatidylglycerol modulates ambient temperature-responsive flowering  Cold Spring Harbor Asia (Gyeongju, Korea)

     

  • Lab Members

    POSTDOCTORAL FELLOWS
    POSTDOCTORAL FELLOWS
    김수진 박사는 서강대학교에서 박사학위를 했다. 박사학위 논문의 주제는 벼에서 비생물적 스트레스에 의해서 발현이 유도되는 유전자에 대한 것이다. 그 후 독일로 건너가서 프라운호퍼 연구소에서 박사후 연구원 생활을 했다. 이 때 연구주제는 형질전환체 옥수수에서 HIV 2G12의 항체를 생산하는 일이었다. PBIO-A에서는 FT와 CSN5A의 상호작용에 대한 연구를 하고 있다. 김수진 박사는 독서, 등산, 트래킹을 좋아한다.

    Dr. Kim received her doctorate from Sogang University for her research on genes induced by abiotic stress in rice. She worked at the Fraunhofer Institute, Germany on the project "Downstream processing for a monoclonal anti-HIV 2G12 antibody from transgenic maize kernels". At PBIOA, she is currently working on FT-FTIP mapping and cell biology. She likes to read, climb and long walks.
    이청희 박사는 미시간 대학교에서 박사학위를 했다. 박사학위 논문의 주제는 애기장대에서 stem cell의 분화 (differentiation)가 조절되는 기작에 대한 것이었다. 2015년에 PBIO-A에 합류했고, 그는 지금 An-1 생태형에서 대기온도 반응성 개화시기를 조절하는 유전자에 대한 연구를 하고 있다. 그는 독서, 걷기, 수영, 사이클링을 즐긴다.

    Dr. Chung Hee Lee received his Ph.D. in biology from the University of Michigan in May 2014 and received a Ph.D. in a study on "how the stem cell specification and differentiation is maintained in Arabidopsis." He became a postdoctoral fellow at PBIO-A in May 2015. He is currently investigating genes involved in the regulation of flowering time in different ecological types of Arabidopsis. He likes reading, walking, swimming and cycling.
    Dr. Kasia Gawarecka received her Ph.D. degree in 2015 at the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences in Warsaw. My Ph.D. The aim of this study was to investigate the effects of glycinoprenols in Arabidopsis thaliana on the development of an animal model of glycinoprenols . She joined PBIOA in August 2017. She loves plants and plays free time games, cooks and draws.
    Dr. Jung received his Ph.D in Plant Biology from Washington University in Saint Louis in USA. During his Ph.D course, he worked on understanding signal transduction pathways in plants under low nutrients such as low potassium and low nitrogen. Then, he moved to Switzerland and did his research about phosphate sensing and signaling in plants. At PBIO-A, he is currently working on post translational modification of SVP/FLM. He likes music, movie and game etc.
    정경숙 박사는 2004년 12월에 PBIO-A 에 들어오게 되었다. 2012년 2월에  박사학위를  받았다.  현재 FT 단백질과 인지질과의 관계,  FT와 TFL1의 antagonist regulation mechanism를 연구 중이다. 여가시간에는 수영을 즐긴다. 
     
    Dr. Kyung Sook Chung joined PBIO-A in December 2004. She received her PhD in February 2012. She is currently studying the relationship between FT protein and phospholipids and the antagonist regulation mechanism of FT and TFL1. She enjoys swimming.

     

    최봉수 박사는 포항공과대학교에서 박사학위를 했다. 박사학위 논문의 주제는 애기장대에서 광합성과 비생리학적 스트레스 저항성에 관여하는 단백질의 새로운 기능에 대한 것이다. 그는 2023년도에 PBIO-A에 합류하여 SVP의 활성화 기작에 대해 연구하고 있다. 최봉수 박사는 여가시간에 농구, 축구, 게임을 즐긴다.

     

    Dr. Choi received his Ph.D. from Pohang University of Science and Technology. The subject of the doctoral dissertation is about new functions of the protein involved in photosynthesis and abiotic stress resistance in Arabidopsis. He joined PBIO-A in December 2022 and is studying the activation mechanism of SVP. Dr. Choi enjoys playing basketball, soccer and games in his spare time.

    Brain Pool Researchers
    Zeeshan Nasim joined PBIOA as a Researcher in 2015, later enrolled as a Ph.D. student in 2016 and graduated in 2021 after which he worked as a postdoc for an year and left PBIOA at the end of 2022. He studied the mechanisms of FLC and FLC-clade genes regulation at epigenetic, transcriptional, posttranscriptional and posttranslational levels, in the context of temperature-responsive flowering time in Arabidopsis. His aim was to utilize computational tools along with the biological practices to serve the plant community. He loves Cricket, the gentleman's game. After working for almost a year at King Abdullah University of Science and Technology (KAUST), he was selected as an excellent foreigner scientist and awarded with the prestigious Brain Pool Fellowship. He’s currently working as a Research Professor.

     

    GRADUATE STUDENTS
    GRADUATE STUDENTS
    윤금민은 2018년 3월 석사과정생으로 입학하여 Flowering에 관여하는 MADS box protein에 대해 연구하고 있다. 취미는 gathering information 으로 항상 랩 멤버들에게 관심을 가지며 즐거운 실험실 생활을 하고 있다. 1대 파티걸 진수현을 이어 2대 파티걸로 열심히 성장하는 중이다.
     
    조주빈은 2022년 3월 석박사 통합과정으로 입학하여 애기장대의 flowering gene의 regulation에 대해 공부하고 있다. 어렸을 때부터 식물을 꾸준히 좋아해 이 곳까지 오게 되었다, 아직은 서툴지만 PBIOA에서의 삶을 즐기고 있다. 취미는 산책, 고양이 사진 찍기와 보드게임이다.

    Jubin Cho joined PBIOA as an integrated PhD program student in March 2022. She is studying the regulation of the flowering time in Arabidopsis. Her love for plants (since her childhood) made her interested in studying flowering and eventually joining PBIOA. She is clumsy (but diligent) and is enjoying her life at PBIOA. Her hobbies list includes walking, taking pictures of cats, and playing board games.
    Nouroz Karim joined PBIOA as an integrated PhD program student in March 2022. He is interested in exploring the genomic diversity-driven differential regulation of flowering time in  Arabidopsis natural accessions. His interest in plant development, especially flowering, led him to join PBIOA. His hobbies include badminton, cicket and watching historical movies.
    Sujin Kim joined PBIOA in September 2022 as an integrated degree student and is currently studying genes that regulate flowering in Arabidopsis. As for now, "she is the super-cute maknae of PBIOA. Plus she is a born-to-be lucky girl whose going to be a great scientist" (her words :D ).
    Shengmin Wang joined PBIOA as an integrated PhD program student in March 2023. He is interested in exploring the differential regulation of flowering time in Arabidopsis. His special interest in exploring the flowering mechanism in ambient temperature led him to join PBIOA. 
    Lab manager and Secretary
    홍향미는 식물대기온도센터의 행정원이다. 연구비 및 각종 행정업무를 총괄하고 있다. 2003년 식물신호네트워크 연구센터가 개소할 때부터 함께 일해왔다. 그 전에는 한국 연구재단에서 근무했다.

    Hong is the administrative manager of the lab. She is responsible for research expenses and various administrative affairs. She has been working with us since 2008. Before she joined the PBIO-A, she worked in ` the plant signal network research center and the Korea Research Foundation.
    김영자 연구원은 2005년에 PBIO-A에 들어왔다. 초기에 TAIL-PCR 관련 실험을 진행하다가 현재는 Lab manager로 실험실에서 진행되는 전반적인 살림을 관리하는 일을 맡고 있다. 늘 따뜻한 미소로 한결같이 PBIO-A 식구들과 함께 해주시는 엄마같은 분이다.

    Kim Young-ja joined PBIO-A in 2005. She was initially involved in TAIL-PCR-related experiments, and now she is in charge of managing overall plant-related experiments in the lab as a lab manager. She is always like a mother with her warm smile and always with her family.
    FORMER MEMBERS
    박사후 연구원
    Suhyun Jin joined PBIO-A in December 2012 and entered the master's program in March 2013. From March 2014, she entered the integrated course for Doctor's program. She got her Ph.D dergree in Feburary, 2020. Then, she worked as a post-doc at PBIOA till June 2023. Now, she is joining Max Planck Institutes, Germany as a Research Scientist.
    Hendry Susila joined us from Indonesia at March 2013 as integrated Master-Ph.D student and completed his doctorate degree in Feburary, 2021. He is from Denpasar, Bali, Indonesia, a tourist spot. He obtained his bachelor's degree in the Faculty of Biology, Gadjah Mada University, Indonesia. Hendry published several high quality research papers inculding a first author Science paper. He recently left for his hometown and started a new journey of his life. We wish him a happy marital life ;). Currently, he is working as Innovation Fellow at ARC Training Centre for Future Crops Development, the Australian National University.
    이정환 교수는 2001년 2월 고려대학교서 박사학위를 취득하고 2003년 2월까지 박사후연구원으로 벼에서 개화시기 조절경로에 작용하는 OsFCA유전자에 대한 연구를 수행하였다. 2003년 3월부터 PBIO-A에 들어와서 온도에 의해 조절되는 개화시기 경로와 조기개화에 관련된 애기장대 돌연변이체를 찾고 있다.[2007-2010 MOEHRD-KRF Research Professor (Korea Research Foundation)]
    현재 그는 전북대학교 교수로 재직중이다.

    Professor Lee Jung-hwan obtained his doctoral degree from Korea University in February 2001 and worked as a postdoctoral researcher until February 2003 to investigate the OsFCA gene that acts on the flowering-time control pathway in rice. Since March 2003, we have come to PBIO-A and are looking for temperature-regulated flowering pathways and Arabidopsis mutants associated with early flowering. 2007-2010 MOEHRD-KRF Research Professor (Korea Research Foundation)] Currently, he is a professor at Chonbuk National University.
    김완희 박사는 2008년 12월 프랑스 파리 제11대학에서 Role of histone acetylation in the function of genome expression을 주제로 생물학 박사학위를 취득하고 2009년 1월에 박사후 연구원으로?랩에 합류하였다. 현재 식물의 온도 센서로서의 micro RNA에 대해 연구하고 있다. (2010-2011 Postdoctoral fellowship (National Research Foundation). 현재 서울대학교에 Cecile Segonzac 교수 연구실에 박사후 연구원으로 있다.

    Dr. Wanhee Kim received his Ph.D. in biology from the University of Paris, France, at the University of Paris, France, on the topic of role of histone acetylation in the function of genome expression. We are currently studying microRNA as a temperature sensor for plants. ( 2010-2011 Postdoctoral fellowship (National Research Foundation). Currently, Professor Cecile Segonzac of the Department of Plant Science and Technology, Seoul National University
    신현영 박사는 2014년 8월 고려대학교에서 JA와 stress에 반응하는 벼와 애기장대의 MAP kinase의 기능 연구를 주제로 박사학위를 받고 2014년 9월에 박사후 연구원으로 PBIO-A에 합류하였다. 현재 숙명여자대학교 남경희 교수 연구실에 박사후 연구원으로 있다.

    In August 2014, Dr. Shin received a Ph.D. in the study of MAP kinase in rice and Arabidopsis responding to JA and stress at Korea University in August 2014. He joined PBIO-A as a postdoctoral researcher in September 2014.
    Currently, Professor Nam Kyunghee is a researcher at Sookmyung Women's University.
    김선영 박사는 2013년 2월 숙명여자대학교에서 AtBAK1과 그의 새로운 downstream component의 기능 연구를 주제로 박사학위를 받고 2014년 3월에 박사후 연구원으로 PBIO-A에 합류하였다.

    In February 2013, Dr. Kim received a Ph.D. In the study of AtBAK1 and its new downstream component at Sookmyung Women's University and joined PBIO-A as a postdoctoral researcher in March 2014.
    Snjezana Juric was born in 1980 in Tuzla, Bosnia and Herzegovina. In 2005, she enrolled in the postgraduate studies in Molecular and Cell Biology at the Faculty of Science, University of Zagreb, and undertook the research work in the Division of Molecular Biology, Rudjer Boskovic Institute (RBI), Zagreb, under the supervision of Prof Hrvoje Fulgosi. Since then, she has been the employee at the RBI, working on the regulation of photosynthesis, trying to define and redefine the functions of thylakoid membrane proteins. She was awarded with two awards for 2009, the Zeljko Trgovcevic Award and the Young Scientists Award. In 2011, she was awarded with the FEBS Short-term Fellowship for research work in Prof Alexander Ruban laboratory at Queen Mary University of London. From September 2011, Snjezana has joined Prof Ji Hoon Ahn laboratory as a postdoctoral researcher.
    Muhammad Fahim is a Post Doctoral Fellow in the lab of Professor Ji Hoon Ahn and is studying the role of small RNAs in the leaf development in Arabidopsis. Fahim recently completed his PhD in Plant Sciences (2007-2011) from The Australian National University and CSIRO Canberra Australia under supervision of Dr. Philip Larkin and Dr. Tony Millar on the "Natural and Engineered Resistance against Wheat streak mosaic virus". When not doing science, he travels and enjoys nature. His photography can be seen on his Flickr page.
    유승관 박사는 2002년 2월 Molecular characterization of ornithine carbamoyltransferase genes from Canavalia lineata의 주제로 서울대학교 생명과학부에서 이학박사학위를 취득하고, 식물발달분자유전학 실험실에서 고등식물에서 극조기 개화를 유도하는 ECL1 유전자의 기능 연구 및 개화에 관련한 돌연변이체에 관심을 갖고 연구를 진행중이다. 탁구, 테니스, 스키 등 운동을 좋아한다.
    반성철 박사는 2004년?2월 고려대학교서 박사학위를 취득하고 2005년 8월까지 Phospholipid signaling에 관한 연구를 수행하다가 미국 Missouri 주에 있는 Donald Danforth Plant Science Center에서 Lipid Signaling을 연구하였다. 2009년 PBIO_A에 합류하여 개화시기에 연관된 유전자들의 Biochemical Function에 관한 연구를 수행중에 있다.
    김재준 박사는 2008년 2월 서울대학교에서 스트레스 생리학을 주제로 박사학위를 취득하고 2008년 4월에 PBIO-A에 합류하였다. 현재 Natural variation에 대한 연구를 중점적으로 수행하며, 개화시기 조절에 관한 signaling에 대한 연구를 진행하고 있다.
    김준기 박사는 2004년 8월 Molecular mechanisms underlying floral initiation and vascular development in Arabidopsis thaliana의 주제로 서울대학교 생명과학부에서 이학박사학위를 취득하고, 2004년 7월부터 PBIO-A에 들어와서 온도에 의해 조절되는 개화시기 경로와 조기개화에 관련된 ILT2 유전자의 기능분석 연구를 한 후 PBIO-A를 떠났다.
    Dr. Hemasundar Alavilli received his Ph.D. in 2017 from Sogang University in Seoul. His Ph.D. study objectives were to understand the functional benefits of polar moss genetic resources in crop improvement and enhancement of abiotic stress tolerance. He worked at PBIOA from October 2017 to April 2019.
    박사과정
    홍 성면 박사는 2003년 3월에 lab에 들어왔으며, 현재는 T-DNA insertion LINE들의 SCREENING과 ARABIDOPSIS의 FT와 TFL1, TOMATO의 SP에 의한 PLANT ARCHITECTURE 형성에 대해 연구하고 있다. 여가시간에는 등산과 독서를 즐긴다. (2006 Seoul Science Fellowship Awardee).
    현재 삼성바이오에피스 (직위: CL3)에서 근무중이다.
    유 성전 박사는 2001년 5월에 PBIO-A에 들어오게 되었다. 2010년 2월에 박사학위를 취득하고 이후 박사후 연구원으로 연구를 진행하고 있다. 관심분야는 FT 유전자의 이동성에 관한 연구와 온도변화에 따른 miRNA의 기능분석이다.
    현재는 대한민국 특허청의 특허심사관 (5급 사무관)으로 재직중이다.
    유소연 박사는 2007년 2월 고려대학교 생명과학대학에서 이학박사 학위를 받았다. 현재 ILT2의 기능 분석에 대한 연구를 수행중이다. 랩에서의 취미는 책보기 특기는 실험하기이며 :) 보통 취미는 악기 연주하기, 음악감상하기, 그리고 기타의 문화 생활이다 [2005 Awardee of Grant for Pre-doctoral Students (Korea Research Foundation)].
    현재는 한국과학문화창의재단에서 근무중이다.
    석박사통합과정
    이예은은 2021년 9월 석박사 통합과정으로 입학하여 애기장대의 flowering에 관여하는 유전자에 대해 공부하고 있다. 연구실에 처음 출근한 날은 생일 다음 날인 3월 11일로 PBIO-A가 생일선물이라고 생각하며 연구실에 큰 애정을 갖고 있는 열정적인 학생이다. 취미는 베이킹과 등산이며, 제주도를 특별하게 좋아하는 그녀에게 주기적인 제주도 여행은 중요한 일정이다.

    Yae-Eun Lee entered PBIO-A as an internship student in March and later enrolled in integrated (Master-PhD) degree program in September 2021. She is studying genes involved in the flowering of Arabidopsis. Her first day in the lab was March 11th, the day after her birthday, so she thinks that PBIO-A is the most valuable birthday present. She likes baking and hiking. She especially loves Jejudo island, and for her, a regular trip to Jejudo island is an important event.
    석사과정  
    Ho Cheol Hwang joined PBIOA in March 2020 as a master's student. He studied about the epigenetic regulation of flowering time in Arabidopsis. The fact that his birthday is Arbor Day, suggests that he was destined to study plants from birth. On the other hand, he got the nickname 'DF Hwang' by promoting lab outing with great drive.
      Hyewon Jeong joined our lab as a Masters degree student and completed her degree in August, 2021. She identified PIF3 as an important player in the ABA-dependent flowering time reulation in Arabidopsis.
    Phanu Tew Serivichyaswat hails from Chiang Rai, Thailand. Having earned B.Sc. (Biotechnology) from Mae Fah Luang University (Thailand) in 2012, he worked at Orchid Biotechnology Research Laboratory to study the molecular basis of orchid-mycorrhiza symbiosis, then joined us in the following year. Ending world hunger is his motivation to study flowering time. He is currently studying the role of microRNA in the regulation of ambient temperature-responsive flowering time.
    He received a master degree in Aug 2017
    강태욱은 2013년 3월 학부연구생으로 PBIO-A에 합류하여 2015년 1학기 석사과정에 입학하였다. 석사과정동안 LFH1 유전자에 대한 연구를 수행했다. 2017년 2월 석사학위를 취득했다.
    Kang Tae-wook joined the PBIO as an undergraduate student in March 2013 and obtained his master's degree in February 2017.
    전아림은 2012년 3월에 석사과정으로 입학하여 PBIO-A에 join하였다. 김완희 박사와함께 miRNA precursor2차 구조가 식물의 온도 반응에 기여하는 역할을 연구하고 있다.
    박태임은 2010년 3월에 PBIO-A에 들어왔다. 현재는 FT/TFL1 family의 유전학적인 상하위 관계에 대한 실험을 진행하고 있다. FT/TFL1 family의 이중 삼중 돌연변이체의 표현형을 관찰하고 발현양의 차이에 대해서 분석을 하고 있다.
    문수현은 2011년 3월에 석사 학위 과정으로 PBIO-A에 join했다. 현재 박사님들께 대기 온도를 인지하는 유전자들의 expression analysis와 그와 관련된 실험들을 배우고 익히고 있다.
    조현정은 2009년에 실험실에 연구원으로 join하였다. 2010년 석사 학위 과정으로 입학하였다. 지금은 대기 온도를 인지하는 유전자를 탐색하고 분리된 유전자의 기능을 분석하고 있다. 실험실에서는 랩 매니저의 역할을 하고 있고 2010년 새로이 들어온 신입생과 함께 밝은 실험실의 분위기를 주도하고 있다.
    김수현은 2009년 2월에 PBIO-A lab에 join했다. 현재는 Arabidopsis 내의 HOS1 gene의 ubiquitination에 관련된 연구를 진행하고 있다. 또한 FT,TFL과 FD,FDP간의 interaction을 규명중이다. 취미는 음악 감상과 독서이며, 실험실의 마스코트로써 항상 최선을 다하는 모습이 아름답다. 현재 삼성바이오로직스에 근무중이다 (직위: 프로).
    정혜승은 2008년 9월에 졸업 논문 관련하여 PBIO-A에 join했다.현재 대기온도와 관련하여 찾아진 ILT1 유전자와 관련하여 개화시기 조절 유전자들과의 상호 관계에 대해 관심을 가지고 연구하고 있다. 취미는 다양한 재료로 독창적인 맛있는 음식을 만드는 것이며, 이러한 취미를 적극적으로 연구에 활용하여 다양한 유전자들의 역할을 규명하는 연구를 수행하고 있다. 현재 유미특허법인의 변리사이다. 
    최미숙은 2003년 2월 PBIO-A연구실의 멤버가 되었다. 영화와 만화책보기를 즐겨 하며, 레크리에이션에 관련된 것을 좋아한다. 연구실에서는 oral tolerance autoimmune disease에 대한 연구와 TFL1 peptide에 대한 연구를 진행중이다.
    정승혜는 2003년 8월부터 PBIO-A에 join하였으며 activation tagging mutagenesis를 이용하여 제조된 mutant population을 대상으로 reverse genetics적 연구방법을 이용하여 유전자의 functional analysis를 수행하고 있다. 또한 BFT의 function에 관한 연구도 진행중이다. 랩에서의 모습은 사진과 다소 차이(???)가 있지만 그래도 귀여운 막내자리를 고수중이다. 취미는 요리와 여행이며 후식으로는 항상 녹차 한잔을 즐긴다.
    박수현은 2004년 2월에 PBIO-A lab에 join했다. 현재는 온도에 의해서 조절되는 개화시기의 경로에 대해서 연구하고 있다. 말은 적지만 조용히 실험하는 새로운 막내의 모습을 보여주고 있는중. ^^ 취미로는 십자수를 즐겨한다.
    그외
    김경은 연구원은 2009년 4월에 PBIO-A에 들어왔다. 현재는 대기 온도에 반응하지 않는 ILT1유전자에 대해 연구를 하고 있으며, 이와 관련하여 ILT1유전자와 관련이 있을 것으로 추정되는 miRNA와의 상관 관계에 대해 연구하고 있다.
    김지선 연구원은 2010년 12월 PBIO-A에 join 하였다. 현재는 실험실에서 진행하고 있는 전반적인 실험 방법에 대해 배우고 있다. 자신이 맡은 일은 끝까지 책임지고 수행하려는 성격이 강하며, 연극, 영화, 뮤지컬 등 공연 보는 것을 좋아한다.
    양정원 연구원은 2002년 2월 'Isolation and characterization a nematode resistance gene from soybean’이란 제목으로 수원대학교에서 석사 학위를 받았으며, 올 2월부터 연구원으로 PBIO-A Lab에 함께하게 되었다 현재 Arabidopsis activation tagging line의 reverse genetics를 통해 유전자 기능분석 및 기능유전체학 DB 구축 작업중이다. 영화보는 것을 무척 즐겨하며 음악도 장르의 구분없이 다 좋아한다.