Name : Woong Sun

Sex : Male

Birthday : March 12, 1969

Country of Citizenship : South Korea (ROK)

Address : Department of Anatomy, Korea University College of Medicine, 126-1 5-ka, Anam-dong Sungbuk-gu, Seoul 136-705

Phone : (Office) 02-2286-1404

E-mail : woongsun@korea.ac.kr

Education

• 1987.03 ~ 1991.02 BS, Department of Molecular Biology, Seoul National University
• 1991.03 ~ 1993.02 MS, Department of Molecular Biology, Seoul National University
• 1993.03 ~ 1997.02 PhD, Department of Molecular Biology, Seoul National University

Academic Appointments

• 1997.08 ~ 2000.06 Postdoctoral Fellow, Department of Biochemistry Osaka University School of Medicine, Japan (Nakamura Lab)
• 2000.09 ~ 2002.08 Postdoctoral Fellow, Department of Neurobiology and Anatomy Wake Forest University School of Medicine North Carolina, USA (Oppenheim Lab)
• 2002.08 ~ 2005.08 Assistant Professor, Department of Anatomy, Korea University College of Medicine
• 2005.09 ~ 2009.08 Associate Professor, Department of Anatomy, Korea University College of Medicine
• 2009.09 ~ 2010.08 Visiting Professor, Dept of Ophthalmology, UCSD
• 2009.09 ~ Present Professor, Department of Anatomy, Korea University College of Medicine

Reviewers, Editors, Society Activities

• Editorial board member of Mol Cells (SCI Journal) and Animal Cells Sys (SCIE Journal), Experimental Neurobiology, Anatomy and Cell Biology, and Development & Reproduction.
• Ad-hoc reviewers of many Journals, such as Neurochem Res, Plos One, J Neurocem, Eur J Neurosci, Neurochem Int, J Neurobiol, BBRC, Exp Mol Med, etc
• Chair of School Committee for Asian-Pacific Society for Neurochemistry 2015
• Council member of Asian-Pacific Society for Neurochemistry (APSN), and Korean Society for Brain and Neural Science (KSBNS)
• Committee member of Korean Society for Molecular and Cellular Biology (KSMCB), Korean Society of Biochemistry and Molecular Biology (KSBMB), Korean Society of Developmental Biology (KSDB).
• International Brain Research Organization (IBRO) Local Organizing Committee member

Awards

• 2011. 대한해부학회 한길연구상 ; Korean association of Anatomist Award
• 2013. 대한해부학회 한길연구상 ; Korean association of Anatomist Award
• 2013. Experimental Neurobiology Award
• 2018. 고려대학교 교우회 우수학술상 ; Korea University Academic Award

Publication list

• 1. Wan Sung Choi, Myung Ok Kim, Byung Ju Lee, Jin Hyun Kim, Woong Sun, Jae Young Seong, Kyungjin Kim (1994) Presence of gonadotropin-releasing hormone mRNA in the rat olfactory piriform cortex, Brain Res 648:148-151


• 2. Dae Kee Lee, Woong Sun, Changduck Kim, Kunsoo Rhee, Thompson EA, Chung Choo Lee, Wan Kyoo Cho, Kyungjin Kim (1994) Murine thymidine kimase in transgenic mice, Transgenics 1:337-347


• 3. Dae Kee Lee, Woong Sun, Kunsoo Rhee, Heysung Cho, Chung Choo Lee, Kyungjin Kim (1994) Analysis of thymidine kinase gene expression in preimplantation mouse embryos, Mol Reprod Dev 39:259-267


• 4. Woong Sun, Dae Kee Lee, Chung Choo Lee, Kyungjin Kim (1996) Differential expression of D-type G1 cyclins during mouse development and liver regeneration in vivo, Mol Reprod Dev 43:414-420


• 5. Dae Kee Lee, Woong Sun, Kunsoo Rhee, Chung Choo Lee, Kyungjin Kim (1996) Regulation of thymidine kinase gene expression during liver regeneration and uterine tissue proliferation in transgenic mice, Transgenics 2:89-98


• 6. Woong Sun, Huberatus Jarry, Wolfgang Wuttke, Kyungjin Kim (1997) Gonadotropin releasing hormone modulates gamma-aminobutyric acid-evoked intracellular calcium increase in immortalized hypothalamic gonadotropin releasing hormone neurons, Brain Res 747:70-77


• 7. Dongho Geum, Woong Sun, Seung Kee Paik, Chung Choo Lee, Kyungjin Kim (1997) Estrogen-induced cyclin D1 and D3 gene expressions during mouse uterine cell proliferation in vivo: differential induction mechanism of cyclin D1 and D3, Mol Reprod Dev 46:450-458


• 8. Sehyung Cho, Jin Han, Woong Sun, Donchan Choi, Hyuk Bang Kwon, Huberatus Jarry, Wolfgang Wuttke, Kyungjin Kim (1997) Evidence for autocrine inhibition of gonadotropin-releasing hormone (GnRH) gene transcription by GnRH in hypothalamic GT1-1 neuronal cells, Brain Res Mol Brain Res 50:51-58


• 9. Woong Sun, Youngsik Choe, Young Jun Lee, Kyungjin Kim (1997) Suppression of GnRH gene expression in GT1-1 hypothalamic neuronal cells: action of protein kinase C, Neuroreport 8:3541-3546


• 10. Neoncheol Jung, Woong Sun, Hojoon Lee, Sehyung Cho, Chanseob Shim, Kyungjin Kim (1998) Gonadotropin-releasing hormone (GnRH) gene regulation by N-methyl-D-aspartic acid in GT1-1 neuronal cells: differential involvement of c-fos and c-jun protooncogenes. Brain Res Mol Brain Res, 61:162-169


• 11. Woong Sun, Hiroshi Funakoshi, Toshikazu Nakamura (1999) Differential expression of hepatocyte growth factor and its receptor, c-Met in the rat retina during development, Brain Res 851:46-53


• 12. Woong Sun, Hiroshi Funakoshi, Kunio Matsumoto, Toshikazu Nakamura (2000) A sensitive quantification method for evaluating the level of hepatocyte growth factor and c-met/HGF receptor mRNAs in the nervous system using competitive RT-PCR, Brain Res Brain Res Protoc 5:190-197


• 13. Woong Sun, Hojoon Lee, Youngsik Choe, Sehyung Cho, Do Han Kim, Kyungjin Kim (2001) Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurons, J Neuroendocrinol 13:249-260


• 14. Woong Sun, Hiroshi Funakoshi, Toshikazu Nakamura (2002) Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS, J Neurosci 22:6537-6548


• 15. Woong Sun, Hiroshi Funakoshi, Toshikazu Nakamura (2002) Localization and functional role of hepatocyte growth factor (HGF) and its receptor c-met in the rat developing cerebral cortex. Brain Res Mol Brain Res 103:36-48


• 16. Jeon J, Kim C, Sun W, Chun H, Park S, Kim H (2002) Cloning and localization of rgpr85 encoding rat G-protein-coupled receptor, Biochem Biophy Res Comm 298:613-618


• 17. Donghou Kim, Eun Hae Kim, Changmee Kim, Woong Sun, Goon Ho Park, Chang Sub Uhm, Hyun Kim (2003) Differential regulation of metallothionein-I, II, and III mRNA expression in the rat brain following kainic acid treatment, Neuroreport 14:679-682


• 18. Woong Sun, Thomas W. Gould, Sharon Vinsant, David Prevette and Ronald W. Oppenheim (2003) Neuromuscular development following the prevention of naturally occurring neuronal death by Bax deletion, J Neurosci 23:7298-7310


• 19. Woong Sun, Ronald W. Oppenheim (2003) Response of motoneurons to neonatal sciatic nerve axotomy in Bax-knockout mice, Mol Cell Neurosci, 24:875-886


• 20. Il Hwan Kim, Soon Kwon Park, Woong Sun, Yunhee Kang, Hyun Taek Kim, Hyun Kim (2004) Spatial learning enhances the expression of inositol 1,4,5 triphosphate 3-kinase A in the hippocampal formation of rat, Mol Brain Res, 124:12-19


• 21. Eun Hae Kim, Tae Sik Kim, Woong Sun, Dal Soo Kim, Hyun-Soo Chung, Dong Ki Kim, Sun-Hwa Park, and Hyun Kim (2004) Differential regulation of metallothionein-I and metallothionein-II mRNA expression in the rat brain following traumatic brain injury. Mol Cells, 18:326-331


• 22. Woong Sun, Adam Winseck, Sharon Vinsant, Ok-hee Park, Hyun Kim, Ronald W Oppenheim (2004) Programmed cell death of adult generated hippocampal neurons is mediated by the pro-apoptotic gene Bax, J Neurosci, 24:11205-11213 (corresponding author)


• 23. Woong Sun, Kun Woo Park, Jeehyung Choe, Im Joo Rhyu, Il Hwan Kim, Soon Kwon Park, Byungil Choi, Sang Hyun Choi, Sun Hwa Park, and Hyun Kim (2005) Identification of novel electroconvulsive shock-induced and activity-dependent genes in the rat. Biophy Biochem Res Comm, 327:848-856


• 24. Jeehyung Choe, Woong Sun, Seung-Yong Yoon, Im Joo Rhyu, Eun Hae Kim, and Hyun Kim (2005) Effect of thymosin beta15 on the branching of developing neurons. Biophy Biochem Res Comm, 331:43-49


• 25. Woong Sun, Thomas W Gould, Jason Newbern, Carol Milligan, So Yoen Choi, Hyun Kim, Ronald W Oppenheim (2005) Phosphorylation of c-Jun in avian and mammalian motoneurons in vivo during programmed cell death: An early reversible event in the apoptotic cascade. J Neurosci, 25:5595-5603 (corresponding author)


• 26. Woong Sun, Yunhee Kang, Il Hwan Kim, Eun Hae Kim, Im Joo Rhyu, Hyun-Ju Kim, Hyun Kim (2006) Inhibition of rat brain inositol 1,4,5 trisphosphate 3-kinase A expression by kainic acid. Neurosci Lett, 392:181-186


• 27. Woong Sun, Kye-Hyun Kim, Mi-Ra Noh, Soon Taek Hong, Younghwa Kim, Hyun Kim (2006) Induction of CITED2 expression in the rat hippocampus following transient global ischemia. Brain Res, 1072(1):15-8


• 28. Younghwa Kim, Eun Hae Kim, Soontaek Hong, Im Joo Rhyu, Jeehyung Choe, Woong Sun, Hyun Kim (2006) Expression of thymosin beta in the rat brain following transient global ischemia. Brain Res, 1085(1):177-182


• 29. Robert R Buss, Woong Sun, Ronald W Oppenheim (2006) Adaptive Roles of Programmed Cell Death during Nervous System Development. Ann Rev Neurosci, 29:1-35


• 30. So Yoen Choi, Dong Ki Kim, Bokkee Eun, Kyungjin Kim, Woong Sun, Hyun Kim (2006) Anti-apoptotic function of thymosin-beta in developing chick spinal motoneurons. Biophy Biochem Res Comm, 346:872-878


• 31. Thomas W. Gould, Robert R. Buss, Sharon Vinsant, David Prevette, Woong Sun, Michael Knudson, Carol E Milligan, Ronald W Oppenheim (2006) Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS. J Neurosci, 26: 8774 – 8786.


• 32. Younghwa Kim, Soontaek Hong, Mi Ra Noh, Soo Young Kim, Pil W Huh, Sun-Hwa Park, Woong Sun, Hyun Kim (2006) Expression of neuron-derived orphan receptor-1 (NOR-1) is selectively induced in the dentate gyrus of the hippocampal formation following transient global ischemia in the rat. Mol Cells, 22:8-12.


• 33. Mi-Ra Noh, Sung Koo Kim, Woong Sun, Soon Kwon Park, Il Hwan Kim, Hyun-Ju Kim, Hyun Kim, Baik-Lin Eun (2006) Neuroprotective Effect of Topiramate on Hypoxic Ischemic Brain Injury in Neonatal Rats. Experimental Neurology, 201:470-478.


• 34. Sung Kun Chun, Woong Sun, Joong Jin Park, Min Whan Jung (2006) Enhanced proliferation of progenitor cells following long-term potentiation induction in the rat dentate gyrus. Neurobiology of Learning and Memory, 86:322-329.


• 35. Woong Sun, Sang-Hyun Choi, Soon Kwon Park, Soon Jung Kim, Eun Hae Kim, Hyun Ju Kim, Hyun Kim (2007) Identification and characterization of novel activity-dependent transcription factors in the rat cortical neurons. J Neurochem, 100:269-278.


• 36. Mi-Yoon Chang, Woong Sun, Wataru Ochiai, Kinichi Nakashima, Soo-Young Kim, Chang-Hwan Park, Jin Sun Kang, Jae-Won Shim, Chun-Sik Kang, Yong-Sung Lee, Jae-Sang Kim, and Sang-Hun Lee (2007) Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells. Mol Cell Biol, 27:4293-4305.


• 37. Soo Young Kim, Hye Sun Chung, Woong Sun, Hyun Kim (2007) Spatiotemporal expression patterns of non-clustered protocadherin family members in the developing rat brain. Neuroscience, 147:996-1021. (Co-corresponding author)


• 38. Woong Sun, Hyun Kim (2007) Neurotrophic role of beta-Thymosins in the development and regeneration of the nervous system. Ann New York Acad Sci, 1112:210-218. (invited review)


• 39. Ok-hee Park, Kea Joo Lee, Im Joo Rhyu, Dongho Geum, Hyun Kim, Robert Buss, Ronald Oppenheim, Woong Sun (2007) Bax-dependent and –independent death of motoneurons after facial nerve injury in adult mice. Eur J Neurosci, 26:1421-1432.


• 40. So Yoen Choi, Mi Ra Noh, Dong Ki Kim, Woong Sun, Hyun Kim (2007) Neuroprotective function of thymosin beta and its derivative peptides on the programmed cell death of the chick and rat neurons. BBRC, 362:587-593. (co-corresponding author)


• 41. Woon Ryoung Kim, Younghwa Kim, Bokkee Eun, Kyungjin Kim, Ok-hee Park, Hyun Kim, Sharon Vinsant, Ronald W. Oppenheim, Woong Sun (2007) Impaired migration in the rostral migratory stream, but spared olfactory function following the elimination of programmed cell death in Bax-KO mice. J Neurosci, 27:14392-14403.


• 42. Jeongyeon Kim, Sukwon Lee, Kyungjoon Park, Ingie Hong, Bomjong Song, Gihoon Son, Heewoo Park, Woon Ryoung Kim, Eunjin Park, Hyun Kim, Changjoong Lee, Woong Sun, Kyungjin Kim, Ki Soon Shin, Sukwoo Choi (2007) Amygdala depotentiation and fear extinction. PNAS, 104:20955-20960.


• 43. Bokkee Eun, Yool Lee, Soontack Hong, Kyungjin Kim, Jae-Sang Kim, Han Woong Lee, Woong Sun, Hyun Kim (2008) Hes6 controls cell proliferation via intraction with CREB binding protein in the PML nuclear body. J Biol Chem, 283:5939-5949. (co-corresponding author)


• 44. Dong Ki Kim, Seung Baek Han, Soon Taek Hong, Yu Jin Choi, Woong Sun, Dongho Geum, Hyun Kim (2008) Expression of Sox11 and Brn transcription factors during development and following transient forebrain ischemia in the rat. Neurosci Lett, 433:259-264.


• 45. A-rong Jung, Tae Woo Kim, Im Joo Rhyu, Hyun Kim, Young Don Lee, Sharon Vinsant, Ronald W Oppenheim, Woong Sun (2008) Misplacement of Purkinje cells during postnatal development in Bax knockout mice: A novel role for programmed cell death in the nervous system? J Neurosci, 28:2941-2948.


• 46. Lee J, Sung YH, Cheong C, Choi YS, Jeon HK, Sun W, Hahn WC, Ishikawa F, Lee HW (2008) TERT promotes cellular and organismal survival independently of telomerase activity. Oncogene, 27:3754-3760.


• 47. Young Woong Kim, Younghwa Kim, Eun Hae Kim, Doyle Koh, Woong Sun, Hyun Kim (2008) Expression and subcellular localization of Thymosin beta15 following kainic acid treatment in the rat brain. BBRC, 371:664-669. (co-corresponding author)


• 48. Gi Hoon Son, Sooyougn Chung, Han Kyoung Choe, Hee-Dae Kim, Sun Mee Baik, Hankyu Lee, Han-Woong Lee, Sukwoo Choi, Woong Sun, Hyun Kim, Sehyung Cho, Kun Ho Lee, Kyungjin Kim (2008) Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production. Proc Natl Acad Sci USA 105:20970-20975.


• 49. Soo Young Kim, Hyun Kim, Woong Sun (2008) Selective suppression of a subset of Bax-dependent neuronal death by a cell permeable peptide inhibitor of Bax, BIP. Animal Cells and Systems 122:211-217.


• 50. Sung Yul Kim, Hyo Jin Lee, Yong Nyun Kim, Sehyoun Yoon, Jong Eun Lee, Woong Sun, Eui-Ju Choi, Ja-Hyun Baik (2008) Striatal-Enriched Protein Tyrosine Phosphatase Regulates Dopaminergic Neuronal Development via Extracellular Signal-Regulated Kinase Signaling. Exp Neurol, 214:69-77.


• 51. Woon Ryoung Kim, Ok-hee Park, Sukwoo Choi, Se-Young Choi, Soon Kwon Park, Kea Joo Lee, Im Joo Rhyu, Hyun Kim, Yeon Kyung Lee, Hyun Taek Kim, Ronald W Oppenheim, Woong Sun (2009) The maintenance of specific aspects of neuronal function and behavior is dependent on programmed cell death of adult-generated neurons in the dentate gyrus. Eur J Neurosci, 29:1408-1421.


• 52. Jeong-Sik Lee, Deok-Jin Jang, Nuribalhae Lee, Hyoung-Gon Ko, Hyoung Kim, Yong-Seok Kim, Byungwoo Kim, Junehee Son, Sung Hyun Kim, Heekyoung Chung, Mun-Yong Lee, Woon Ryoung Kim, Woong Sun, Min Zhuo, Ted Abel, Bong-Kiun Kaang, Hyeon Son (2009) Induction of neuronal VEGF expression by cAMP in the dentate gyrus of the hippocampus is required for antidepressant-like behaviors. J Neurosci, 29:8493-8505.


• 53. Jong Won Lee, Woon Ryoung Kim, Woong Sun, Min Whan Jung (2009) Role of dentate gyrus in aligning internal spatial map to external landmark. Learning and Memory, 16:530-536.


• 54. Sung Kun Chun, Woong Sun, Min Whan Jung (2009) LTD induction suppresses LTP-induced hippocampal adult neurogenesis. NeuroReport, 20:1279-1283.


• 55. Seun Baek Han, Byung Il Choi, Dongmin Lee, Sun Ho Kee, Woong Sun, Hyun Kim (2009) Regulation of AHI1 expression in adult brain brain: Implication in hypothalamic feeding control. BBRC, 390:535-540.


• 56. Kim IH, Park SK, Hong ST, Jo YS, Kim EJ, Park EH, Han SB, Shin HS, Sun W, Kim HT, Soderling SH, Kim H. (2009) Inositol 1,4,5-trisphosphate 3-kinase a functions as a scaffold for synaptic Rac signaling. J Neurosci. 29:14039-14049.


• 57. Lee J, Jo YS, Sung YH, Hwang IK, Kim H, Kim SY, Yi SS, Choi JS, Sun W, Seong JK, Lee HW (2010) Telomerase deficiency affects normal brain functions in mice. Neurochem Res. 35:211-218.


• 58. Eun BK, Cho B, Moon Y, Kim SY, Kim K, Kim H, Sun W (2010) Induction of neuronal apoptosis by expression of Hes6 via p53-dependent pathway. Brain Res. 8:1313-1318.


• 59. Kim KS, Yoon YR, Lee HJ, Yoon S, Kim SY, Shin SW, An JJ, Kim M, Choi SY, Sun W, Baik JH (2010) Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors. J Biol Chem. 285:8905-8917.


• 60. Park J, Kim Y, Lee S, Park JJ, Park ZY, Sun W, Kim H, Chang S (2010) SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane. J Cell Sci 123:1742-1750


• 61. Kim SY, Mo JW, Han S, Choi SY, Han SB, Moon BH, Rhyu IJ, Sun W, Kim H (2010) The expression of non-clustered protocadherins in adult rat hippocampal formation and the connecting brain regions. Neuroscience 170:189-199.


• 62. Moon Y, Choi SY, Kim K, Kim H, Sun W (2010) Expression of connexin29 and 32 in the penumbra region after traumatic brain injury of mice. Neuroreport 21:1135-1139.


• 63. Kim WR, Chun SK, Kim TW, Kim H, Ono K, Takebayashi H, Ikenaka K, Oppenheim RW, Sun W (2010) Evidence for the spontaneous production but massive programmed cell death of new neurons in the subcallosal zone of the postnatal mouse brain. Eur J Neurosci 33:599-611.


• 64. Joo Y, Hong BH, Kim J, Chang KA, Liew H, Kim S, Sun W, Kim JH, Chong YH, Suh YH, Kim HS (2010) Amyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells. Plos One 5:e14203.


• 65. Sun W, Kim H, Moon Y (2010) Control of neuronal migration through rostral migratory stream in mice. Anat Cell Biol 43:269-279.


• 66. Choe HK, Son GH, Chung S, Kim M, Sun W, Kim H, Geum D, Kim K (2011) Maternal stress retards fetal development in mice with transcriptome-wide impact on gene expression profiles of the limb. Stress 14:194-204.


• 67. Kim WR, Sun W (2011) Programmed Cell Death (PCD) during Postnatal Development of the Rodent Nervous System, Development Growth and Differentiation 53:225-235 (invited review).


• 68. Kim TW, Kim H, Sun W (2011) Spontaneous reactive astrogliosis in the dentate gyrus of Bax-deficient mice. Mol Cells 31:1-10.


• 69. Moon YH, Kim JY, Choi SY, Kim K, Kim Hm Sun W (2011) Induction of ERM molecules following cryogenic traumatic brain injury of the mouse cortex. Neuroreport, 22:304-308.


• 70. Eun B, Kim HJ, Kim SY, Kim TW, Hong ST, Choi KM, Shim JK, Moon Y, Son GH, Kim K, Kim H, Sun W (2011) Induction of Per1 expression following an experimentally induced epilepsy in the mouse hippocampus. Neurosci Lett, 498(2):110-3


• 71. Wenlin Li, Woong Sun, Yu Zhang, Wanguo Wei, Tongxiang Lin, Janghwan Kim, Xiaolei Wang, Kang Zhang, Sheng Ding (2011) Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors. PNAS, 108(20):8299-304.


• 72. Nacev BA, Low WK, Huang Z, Su TT, Su Z, Alkuraya H, Kasuga D, Sun W, Träger M,Braun M, Fischer G, Zhang K, Liu JO (2011) A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog. J Pharmacol Exp Ther. 338(2):466-75.


• 73. Cai Ying, Geum-Sil Cho, Chung Ju, Si-Ling Wang, Jong Hoon Ryu, Chan Young Shin, Hee-Sun Kim, Kung-Woo Nam, Angela M. A. Anthony Jalin, Woong Sun, In-Young Choi, Won-Ki Kim (2011) Activated microglia are less vulnerable to hemin toxicity due to nitric oxide-dependent inhibition of JNK and p38 MAPKs activation. J Immunol, 187(3):1314-21.


• 74. Kim TW, Moon Y, Kim K, Lee JE, Koh HC, Rhyu IJ, Kim H, Sun W (2011) Dissociation of progressive dopaminergic neuronal death and behavioral impairments by Bax deletion in a mouse model of Parkinson's diseases. PLoS One. 6(10):e25346.


• 75. Cho BK, Kim HJ, Kim H, Sun W (2011) Changes in the histone acetylation patterns during the development of the nervous system. Exp Neurobiol 20:81-84.


• 76. Moon Y, Kim HJ, Kim JY, Kim H, Kim WR, Sun W (2011) Different expression of human GFAP promoter-derived GFP in different subsets of astrocytes in the mouse brain. Animal Cells and Systems 15(4):268-273.


• 77. Kim JY, Choi SY, Kim H, Sun W. (2011) Effect of Strychinine, a Glycine Inhibitor, on the Programmed Cell Death of Motoneurons during the Chick Development. Exp Neurobiol. 20(4):176-80.


• 78. Harkewicz R, Du H, Tong Z, Alkuraya H, Bedell M, Sun W, Wang X, Hsu YH, Esteve-Rudd J, Hughes G, Su Z, Zhang M, Lopes VS, Molday RS, Williams DS, Dennis EA, Zhang K (2012) Essential role of ELOVL4 in very long chain fatty acid synthesis and retinal function. J Biol Chem. 30;287(14):11469-80.


• 79. Kim WR, Kim JY, Moon Y, Kim HJ, Kim H, Sun W (2012) Regional difference of reactive astrogliosis following traumatic brain injury revealed by hGFAP-GFP transgenic mice. Neurosci Lett 513(2):155-9.


• 80. Kim HW, Oh SH, Kim JW, Cho B, Park IS, Sun W, Rhyu IJ (2012) Efficient and accurate analysis of mitochondrial morphology in a whole cell with a high-voltage electron microscopy. J Electron Microsc (Tokyo) 61(2):127-31.


• 81. Lee D, Lee HW, Hong S, Choi BI, Kim HW, Han SB, Kim IH, Bae JY, Bae YC, Rhyu IJ, Sun W, Kim H (2012) Inositol 1,4,5 trisphosphate 3-kinase A is a novel microtubule-associated protein: PKA-dependent phosphoregulation of microtubule binding affinity. J Biol Chem 287(19):15981-95.


• 82. Kim HJ, Kim JY, Sun W (2012) Age-dependent changes in the subcallosal zone neurogenesis of mice. Neurochem Int. 61:879-884.


• 83. Mo J, Choi S, Ahn PG, Sun W, Lee HW, Kim H (2012) PDZ-scaffold protein, Tamalin promotes dendritic outgrowth and arborization in rat hippocampal neuron. Biochem Biophys Res Commun. 422(2):250-255.


• 84. Mo J, Lee D, Hong S, Han S, Yeo H, Sun W, Choi S, Kim H, Lee HW. (2012) Preso regulation of dendritic outgrowth through PI(4,5)P2-dependent PDZ interaction with βPix. Eur J Neurosci. 36(1):1960-1970.


• 85. Cho B, Choi SY, Park OH, Sun W, Geum D. (2012) Differential expression of BNIP family members of BH3-only proteins during the development and after axotomy in the rat. Mol Cells. 33:605-610.


• 86. Choi EY, Yang JW, Park MS, Sun W, Kim H, Kim SU, Lee MA. (2012) Transgenic mice expressing yellow fluorescent protein under control of the human tyrosine hydroxylase promoter. J Neurosci Res. 90(10):1949-1959.


• 87. Kim HJ, Sun W. Adult neurogenesis in the central and peripheral nervous systems. (2012) Int Neurourol J. 16(2):57-61.


• 88. Han S, Hong S, Lee D, Lee MH, Choi JS, Koh MJ, Sun W, Kim H, Lee HW. (2012) Altered expression of synaptotagmin 13 mRNA in adult mouse brain after contextual fear conditioning. Biochem Biophys Res Commun. 425:880-885.


• 89. Park CR, Kim DK, Cho EB, You DJ, Luc do Rego J, Vaudry D, Sun W, Kim H, Seong JY, Hwang JI. (2012) Spatiotemporal expression and functional implication of CXCL14 in the developing mice cerebellum. Mol Cells. 34:289-293.


• 90. Kim JY, Choi SY, Moon Y, Kim HJ, Chin JH, Kim H, Sun W. (2012) Different expression patterns of Phactr family members in normal and injured mouse brain. Neuroscience. 221:37-46.


• 91. Lee JW, Kim WR, Sun W, Jung MW (2012) Disruption of Dentate Gyrus Blocks Effect of Visual Input on Spatial Firing of CA1 Neurons. J Neurosci 32:12999-3003.


• 92. Younghwa Kim, Woong Sun (2012) Distribution of Doublecortin Immunoreactivities in developing chick retina. Applied Microscopy. 548:196-200.


• 93. Moon Y, Kim H, Sun W (2012) Characterization of embryonic cortical neuron death in prolonged cell suspension. Neurosci Lett. 531:155-159.


• 94. Choi SY, Kim JY, Kim HW, Cho BK, Cho HM, Oppenheim RW, Kim H, Rhyu IJ, Sun W (2013) Drp1-mediated mitochondrial dynamics and survival of developing chick motoneurons during the period of neuronal programmed cell death. FASEB J 27:51-62.


• 95. Yonghye Moon, Joo Yeon Kim, So Yoen Choi, Hyo Min Cho, Hyun Kim, and Woong Sun (2013) Expression of ezrin in subventricular zone neural stem cells and their progeny in adult and developing mice. Histochem and Cell Biol. 139:403-413.


• 96. Zhao J, Sun W, Cho HM, Ouyang H, Li W, Lin Y, Do J, Zhang L, Ding S, Liu Y, Lu　P, Zhang K (2013) Integration and long distance axonal regeneration in CNS from transplanted primitive neural stem cells. J Biol Chem. 288:164-168. (co-first authored paper)


• 97. Moon Y, Yeon Kim J, Ryoung Kim W, Jung Kim H, Jee Jang M, Nam Y, Kim K, Kim H, Sun W. (2013) Function of Ezrin-Radixin-Moesin Proteins in Migration of Subventricular Zone-Derived Neuroblasts Following Traumatic Brain Injury. Stem Cells. 31:1696-705.


• 98. Kim WR, Sun W. (2013) Enhanced odor discrimination learning in aged Bax-KO mice. Neurosci Lett, 548:196-200.


• 99. Cho BK, Choi SY, Cho HM, Kim HJ, Sun W. (2013) Physiological and Pathological Significance of Dynamin-like protein 1 (Drp1)-Dependent Mitochondrial Fission in the Nervous System. Exp Neurobiol, 22:149-157.


• 100. Kim WR, Sun W (2013) Postnatal development of subcallosal zone following suppression of programmed cell death in Bax-deficient mice. Dev and Rep, 17:179-186.


• 101. Kim TW, Cho HM, Choi SY, Suguira Y, Hayasaka T, Setou M, Koh HC, Hwang EM, Park JY, Kang JS, Kim HS, Kim H, Sun W. (2013) (ADP-ribose) polymerase 1 and AMP-activated protein kinase mediate progressive dopaminergic neuronal degeneration in a mouse model of Parkinson’s disease. Cell Death & Dis, 4:e919.


• 102. Saiyong Zhu, Rajesh Ambasudhan, Woong Sun, Hyun Jung Kim, Maria Talantova, Xiaojing Wang, Mingliang Zhang, Yu Zhang, Timothy Laurent, James Parker, Han-Seop Kim, Jeffrey D Zaremba, Sofiyan Saleem, Sara Sanz-Blasco, Eliezer Masliah, Scott R McKercher, Yee Sook Cho, Stuart A Lipton, Janghwan Kim, Sheng Ding (2014) Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells. Cell Research 24(1):126-129.


• 103. Kim WR, Jang MJ, Joo S, Sun W, Nam Y (2014) Surface-printed microdot array chips for the quantification of axonal collateral branching of a single neuron in vitro. Lab Chip, Feb 21; 14(4):799-805. (Co-correspondence).


• 104. Kyung Eun Lee, Jihae Seo, Jiheon Shin, Eun Hye Ji, Jiwon Roh, Joo Yeon Kim, Woong Sun, Jonas Muhr, Sanghyuk Lee, and Jaesang Kim (2014) Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous system. PNAS, 111:2794-2799.


• 105. Dongmin Lee, Seungrie Han, Seungkyun Woo, Hyun Woo Lee, Woong Sun, Hyun Kim (2014) Enhanced expression and purification of inositol 1,4,5-tirsphosphate 3-kinase A through use of the pCold1-GST vector and a C-terminal hexahistidine tag in E. Coli. Protein Expression and Purification, 97:72-80.


• 106. Hye Jin Nam, Kyungjin Boo, Dongha Kim, Dong-Hee Han, Han Kyoung Choe, Chang Rok Kim, Woong Sun, Hyun Kim, Kyungjin Kim, Ho Lee, Eric Metzger, Roland Schuele, Seung-Hee Yoo, Joseph S. Takahashi, Sehyung Cho, Gi Hoon Son, Sung Hee Baek (2014) Phosphorylation of LSD1 by PKCα Is Crucial for Circadian Rhythmicity and Phase Resetting. Mol Cell, 53:791-805.


• 107. Eun Soo Lee, Woon Ryoung Kim, Younghwa Kim, Hyun Woo Lee, Hyun Kim, Woong Sun (2014) Polarized and stage-dependent distribution of the immunoreactivity for novel PDZ binding protein Preso1 in the adult neurogenic regions. Endocrinol and Metab, 29:349-355.


• 108. Hyo Min Cho, Joo Yeon Kim, Hyun Kim, Woong Sun (2014) Phosphatase and actin regulator 4 is associated with intermediate filaments in adult neural stem cells and their progenitor astrocytes. Histochem Cell Biol, 142(4):411-419.


• 109. Bongki Cho, Hyo Min Cho, Hyun Jung Kim, Jaehoon Jeong, Sang Ki Park, Eun Mi Hwang, Jae-Yong Park, Woon Ryoung Kim, Hyun Kim and Woong Sun (2014) CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation. Exp Mol Med, 46:e105.


• 110. Kim JH, Sun W, Han DW, Moon HJ, Lee J (2015) iNSC suppress macrophage-induced inflammation by repressing COX-2. In Vitro Cell Dev Biol Anim. 51(2):157-164.


• 111. Chang WH, Kim H, Sun W, Kim JY, Shin YI, Kim YH (2015) Effects of extradural cortical stimulation on motor recovery in a rat model of subacute stroke. Restor Neurol Neurosci. 33(5):589-96.


• 112. Mo J, Kim CH, Lee D, Sun W, Lee HW, Kim H (2015) Early growth response 1 (Egr-1) directly regulates GABA(A) receptor α2, α4, and θ subunits in the hippocampus. J Neurochem. 133(4):489-500.


• 113. R Shaker M, Kim JY, Hyun K, Sun W (2015) Identification and characterization of secondary neural tube-derived embryonic neural stem cells in vitro. Stem Cells Dev. 24(10):1171-81.


• 114. Kim JH, Sun W, Han DW, Lim DJ, Lee J. (2015) Induced neural stem cells have protective effects on cortical neuronal cells in vitro. Neurol Sci. 36(4):527-34.


• 115. Kim WR, Lee JW, Sun W, Lee SH, Choi JS, Jung MW. (2015) Effect of dentate gyrus disruption on remembering what happened where. Frontiers Behav Neurosci. 9:170.


• 116. Joo S, Kim JY, Lee E, Hong N, Sun W, Nam Y. (2015) Effects of ECM protein micropatterns on the migration and differentiation of adult neural stem cells. Sci Rep. 5:13043.


• 117. Byeon JH, Kim GH, Kim JY, Sun W, Kim H, Eun BL. (2015) Cognitive Dysfunction and Hippocampal Damage Induced by Hypoxic-Ischemic Brain Injury and Prolonged Febrile Convulsions in Immature Rats. J Korean Neurosurg Soc. 58(1):22-9.


• 118. Cho HM, Sun W. (2015) Control of Mitochondrial Dynamics by Fas-induced Caspase-8 Activation in Hippocampal Neurons. Exp Neurobiol. 24(3):219-25.


• 119. Kim HJ, Shaker MR, Cho B, Cho HM, Kim H, Kim JY, Sun W. (2015) Dynamin-related protein 1 controls the migration and neuronal differentiation of subventricular zone-derived neural progenitor cells. Sci Rep. 5:15962.


• 120. Choi SY, Pang K, Kim JY, Ryu JR, Kang H, Liu Z, Kim WK, Sun W, Kim H, Han K. (2015) Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders. Mol Brain. 8(1):74.


• 121. Lee KH, Lee H, Yang CH, Ko JS, Park CH, Woo RS, Kim JY, Sun W, Kim JH, Ho WK, Lee SH. (2015) Bidirectional Signaling of Neuregulin-2 Mediates Formation of GABAergic Synapses and Maturation of Glutamatergic Synapses in Newborn Granule Cells of Postnatal Hippocampus. J Neurosci. 35(50):16479-93.


• 122. Kim JY, Choi K, Shaker MR, Lee JH, Lee B, Lee E, Park JY, Lim MS, Park CH, Shin KS, Kim H, Geum D, Sun W. (2015) Promotion of Cortical Neurogenesis from the Neural Stem Cells in the Adult Mouse Subcallosal Zone. Stem Cells. [Epub ahead of print]


• 123. Choi I, Choi DJ, Yang H, Woo JH, Chang MY, Kim JY, Sun W, Park SM, Jou I, Lee SH, Joe EH. (2016) PINK1 expression increases during brain development and stem cell differentiation, and affects the development of GFAP-positive astrocytes. Mol Brain. 9(1):5.


• 124. Lee E, Choi J, Jo Y, Kim JY, Jang YJ, Lee HM, Kim SY, Lee HJ, Cho K, Jung N, Hur EM, Jeong SJ, Moon C, Choe Y, Rhyu IJ, Kim H, Sun W. (2016) ACT-PRESTO: Rapid and consistent tissue clearing and labeling method for 3-dimensional (3D) imaging. Sci Rep. 6:18631.


• 125. Kim JY, Sun W, Park E, Lee J, Kim H, Shin YI, Kim YH, Chang WH. (2016) Day/night difference in extradural cortical stimulation for motor relearning in a subacute stroke rat model. Restor Neurol Neurosci. 34(3):379-87


• 126. Chung S, Kim IH, Lee D, Park K, Kim JY, Lee YK, Kim EJ, Lee HW, Choi JS, Son GH, Sun W, Shin KS, Kim H. (2016) The role of inositol 1,4,5-trisphosphate 3-kinase A in regulating emotional behavior and amygdala function. Sci Rep. 6:23757


• 127. Ryu JR, Hong CJ, Kim JY, Kim EK, Sun W, Yu SW. (2016) Control of adult neurogenesis by programmed cell death in the mammalian brain. Mol Brain. 9:43


• 128. Jang MJ, Kim WR, Joo S, Ryu JR, Lee E, Nam Y, Sun W. (2016) Cell-Type Dependent Effect of Surface-Patterned Microdot Arrays on Neuronal Growth. Front Neurosci. 10:217


• 129. Lee E, Kim HJ, Sun W. (2016) See-Through Technology for Biological Tissue: 3-Dimensional Visualization of Macromolecules. Int Neurourol J. 20(Suppl 1): S15-22.


• 130. Ryu JR, Jang MJ, Jo Y, Joo S, Lee DH, Lee BY, Nam Y, Sun W. (2016) Synaptic compartmentalization by micropatterned masking of a surface adhesive cue in cultured neurons. Biomaterials. 92:46-56.


• 131. Rhee YH, Yi SH, Kim JY, Chang MY, Jo AY, Kim J, Park CH, Cho JY, Choi YJ, Sun W, Lee SH. (2016) Neural stem cells secrete factors facilitating brain regeneration upon constitutive Raf-Erk activation. Sci Rep.6:32025.


• 132. Choi Y, Hwang do W, Kim MY, Kim JY, Sun W, Lee DS. (2016) Transgenic mouse expressing optical MicroRNA reporter for monitoring MicroRNA-124 action during development. Front Mol Neurosci. 9:52.


• 133. Yim N, Ryu SW, Choi K, Lee KR, Lee S, Choi H, Kim J, Shaker MR, Sun W, Park JH, Kim D, Heo WD, Choi C. (2016) Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module. Nat Commun. 7:12277.


• 134. Jo Y, Cho HM, Sun W, Ryu JR. (2017) Localization of Dynamin-related protein 1 and its potential role in lamellipodia formation. Histochem Cell Biol. 148(1):13-20.


• 135. Cho B, Cho HM, Jo Y, Kim HD, Song M, Moon C, Kim H, Kim K, Sesaki H, Rhyu IJ, Kim H, Sun W.(2017) Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division. Nat Commun. 2017 Jun 9;8:15754.


• 136. Lee Y, Kim D, Ryu JR, Zhang Y, Kim S, Kim Y, Lee B, Sun W, Han K. Phosphorylation of CYFIP2, a component of the WAVE-regulatory complex, regulates dendritic spine density and neurite outgrowth in cultured hippocampal neurons potentially by affecting the complex assembly. Neuroreport. 2017 Aug 16;28(12):749-754.


• 137. Cho B, Sun W. CoMIC, the hidden dynamics of mitochondrial inner compartments. BMB Rep. 2017 Dec;50(12):597-598.


• 138. Lee JM, Moon JY, Shaker MR, Sun W, Chung BG. Uniform-sized neurosphere-mediated motoneuron differentiation in microwell arrays. Electrophoresis. 2017 Dec;38(24):3161-3167.


• 139. Yoon KW, Yang HS, Kim YM, Kim Y, Kang S, Sun W, Naik UP, Parise LV, Choi EJ. CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1. Sci Rep. 2017 Sep 22;7(1):12178.


• 140. Lee Y, Ryu JR, Kang H, Kim Y, Kim S, Zhang Y, Jin C, Cho HM, Kim WK, Sun W, Han K. Characterization of the zinc-induced Shank3 interactome of mouse synaptosome. Biochem Biophys Res Commun. 2017 Dec 16;494(3-4):581-586.


• 141. Song JJ, Oh SM, Kwon OC, Wulansari N, Lee HS, Chang MY, Lee E, Sun W, Lee SE, Chang S, An H, Lee CJ, Lee SH. Cografting astrocytes improves cell therapeutic outcomes in a Parkinson's disease model. J Clin Invest. 2018 Jan 2;128(1):463-482.

Book chapters

• 1. Ronald W Oppenheim, Carol Milligan, and Woong Sun (2010) Programmed cell death during nervous system development: Mechanisms, regulation, functions and implications for neurobehavioral ontogeny. In: Handbook of Behavioral and Comparative Neuroscience. Eds Mark Blumberg, John Freeman, Scott Robinson, Oxford Press.

Research Topic

Dr. Sun earned his BS, MS and Ph.D degrees in molecular biology from the Seoul National University, Seoul, Korea. As a postdoctoral fellow, he joined Nakamura Lab of dept. Biochemistry, Osaka University in 1997, and Oppenheim Lab of dept. Neurobiology and Anatomy, Wake Forest University in 2000. He served as assistant/associate professor from 2002 and was appointed professor since September 2009 in the department of Anatomy, Korea University College of Medicine. Dr. Sun’s research aims to understand the mechanisms of neuron production and circuit integration during the embryonic development and in the adult neurogenesis context. Currently his studies focus on histo-morphogenesis of brain and spinal cord using stem cell research and the development of novel histological techniques.

• Molecular and Cellular Biology
• Basic Histology
• Neuroanatomy
• Embryology
• Techniques for Biomedical Researches

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