Phone: 82-2-3290-4922
Email: ghseol@korea.ac.kr
FIELDS OF INTEREST
Intracellular Ca2+, Neuroinflammation, Oxidative Stress, Vascular Dysfunction, Cognitive Impairment
2025-Present: President, Korean Educational Association of Integrative Medicine
2022-Present: Editor, Frontiers in Medicine
2022-2023: Editor, Frontiers in Pediatrics
Choi IY, Kim YJ, Kim SY, Lee MK, Seol GH*. (2025) Rb1 restores palmitic acid-induced reduction of Ca2+ influx by activating PLC in EA cells and PLD in MOVAS cells. Biomed Pharmacother. 184:117927
Son JW, Kang P, Min SS, Seol GH*. (2025) Differential effects of clary sage (Salvia sclarea L.) oil and linalyl acetate on depression levels in diabetic foot ulcer patients with T2DM: a randomized blinded controlled trial. Front Med (Lausanne). 12:1523441
Kim YJ, Lee MK, Kim U, Lee JM, Seol GH*. (2024) Lavandula angustifolia Mill. inhibits high glucose and nicotine-induced Ca2+ influx in microglia and neuron-like cells via two distinct mechanisms. Biomed Pharmacother. 177:117062
You J, Shin YK, Seol GH*. (2024) Alleviating effect of lavender (Lavandula angustifolia) and its major components on postherpetic pain: a randomized blinded controlled trial. BMC Complement Med Ther. 24(1):54
Seo E, Cho Y, Lee JM, Seol GH*. (2023) Inhalation of Pelargonium graveolens Essential Oil Alleviates Pain and Related Anxiety and Stress in Patients with Lumbar Spinal Stenosis and Moderate to Severe Pain. Pharmaceuticals (Basel). 17(1):1
Sung H, Han AY, Seol GH*. (2023) BodyThink program-based body image education improves Korean adolescents' attitudes toward cosmetic surgery: randomized controlled trial. BMC Nurs. 22(1):481
Lee SW, Shin YK, Lee JM, Seol GH*. (2023) Inhalation of Origanum majorana L. essential oil while working reduces perceived stress and anxiety levels of nurses in a COVID-19 intensive care unit: a randomized controlled trial. Front Psychiatry. 14:1287282
Park J, Shin YK, Kim U, Seol GH*. (2023) Ginsenoside Rb1 Reduces Hyper-Vasoconstriction Induced by High Glucose and Endothelial Dysfunction in Rat Aorta. Pharmaceuticals (Basel). 16(9):1238
Kim U, Shin YK, Park J, Seol GH*. (2023) Codonopsis lanceolata Extract Restores Smooth Muscle Vasorelaxation in Rat Carotid Arteries Even under High Extracellular K+ Concentrations. Nutrients. 15(17):3791
Shin YK, Seol GH*. (2023) Effects of linalyl acetate on oxidative stress, inflammation and endothelial dysfunction: can linalyl acetate prevent mild cognitive impairment? Front Pharmacol.. 14: 1233977
Kim JY, Shin YK, Seol GH*. (2023) Incidence and risk factors for pressure injury in hospitalized non-small cell lung cancer patients: A retrospective observational study. J Tissue Viability. Online ahead of print
Kim EG, Chang W, Shin S, Adhikari AS, Seol GH, Song DY, Min SS. (2023) Maternal separation in mice leads to anxiety-like/aggressive behavior and increases immunoreactivity for glutamic acid decarboxylase and parvalbumin in the adolescence ventral hippocampus. Korean J Physiol Pharmacol. 27(1): 113-125.
Kim YJ, Shin YK, Seo E, Seol GH*. (2022) Astrocytes Reduce Store-Operated Ca2+ Entry in Microglia under the Conditions of an Inflammatory Stimulus and Muscarinic Receptor Blockade. Pharmaceuticals (Basel). 15(12): 1521.
Chang W, An J, Seol GH, Han SH, Yee J, Min SS. (2022) Trans-Anethole Alleviates Trimethyltin Chloride-Induced Impairments in Long-Term Potentiation. Pharmaceutics. 14(7): 1422.
Seo E, Shin YK, Hsieh YS, Lee JM, Seol GH*. (2022) Linalyl acetate restores colon contractility and blood pressure in repeatedly stressed-ulcerative colitis rats. Environ Health Prev Med. 27(0): 27.
Han AY, Ha SM, Shin YK, Seol GH*. (2022) Ginsenoside Rg-1 prevents elevated cytosolic Ca2+ via store-operated Ca2+ entry in high-glucose-stimulated vascular endothelial and smooth muscle cells. BMC Complement Med Ther. 22(1): 166.
[저서] (2024) Human Physiology, 2nd ed. (생리학 2판), 현문사
[저서] (2023) (초등학교) 보건: 5~6, 지구문화
[저서] (2023) (초등학교) 보건: 교사용 지도서: 5~6학년, 지구문화
[저서] (2021) Human Physiology, 1st ed. (생리학 1판), 현문사
[역서] (2020) Human Diseases, 8th ed. (병태생리학 8판), 바이오사이언스
[역서] (2014) Essentials of Anatomy and Physiology (해부생리학), 8th ed., 현문사
[역서] (2014) Human Diseases, 7th ed. (병태생리학 7판), 바이오사이언스
[역서] (2014) Introduction to Clinical Pharmacology, 7th ed. (임상약리학 7판), 엘스비어코리아
[역서] (2013) Color Atlas of Pathophysiology (그림으로 이해하는 병태생리학), 서울메디메디아
[역서] (2013) Pathophysiology (병태생리학: 질병의 경과와 회복 촉진), 정문각
[저서] (2013) Essential of medical terminology (에센스) 의학용어, 메디시언
[역서] (2010) Pharmacology (약리학), 정문각
[역서] (2009) Human Diseases, 6th ed. (병태생리학 6판), 바이오사이언스
[역서] (2009) Comprehensive Stress Management (포괄적 스트레스 관리), 아카데미아
PREVENTIVE EFFECTS AND REGULATORY MECHANISMS OF NATURAL PRODUCTS AND EXTRACTS ON NEURONAL AND CARDIOVASCULAR FUNCTIONS IN HEALTH AND DISEASE
Our research focuses on the preventive effects and underlying mechanisms the regulation of natural products and extracts on neuronal and cardiovascular functions in health and disease. Current studies seek to better understand the social-environmental risk factors determinants of the stress response and how excessive stress hormone production contributes to cardiovascular and neurobiological disorders, including dementia. Consequently, these studies demonstrate that the regulation of the social-environmental risk factors plays a central role in the modulation of neuronal and cardiovascular functions and may be an important determinant in brain function and animal behavior.
Main topics of their research include 1) stress vulnerability and transition to cardio-metabolic disease, 2) preventive effects and underlying mechanisms of natural products and extracts on the social-environmental risk factors involved in acute and chronic diseases.
2024.05-2027.04 [한국연구재단] 개인기초연구(이공)우수연구-중견연구(유형1) (725,895,000원) 흰쥐에서 고혈당/고혈압에 의한 이상지질혈증 수준이 인지장애에 미치는 성별에 따른 핵심 기전과 후보 생리활성 천연물 발굴 및 예방 기술 규명 (연구책임자)
2021.03-2024.02 [한국연구재단] 개인기초연구사업 (이공)(유형1-2)중견연구 (587,729,000원) 청소년기 흰쥐에서 불균형 식이에 의한 인슐린 저항성이 인지기능 저하와 정서 장애에 미치는 성별에 따른 핵심 기전 및 리나릴 아세테이트를 활용한 예방 기술 규명 (연구책임자)
2018.06-2021.05 [한국연구재단] 이공학개인기초연구사업 기본연구 (162,500,000원) 장운동과다증을 동반한 만성스트레스로 유발된 고혈압 동물모델에서 방향성 천연물 추출물의 제어기전 연구 (연구책임자)
2016.11-2018.10 [한국연구재단] 이공학개인기초연구사업 기본연구 (100,000,000원) 방향성 천연물의 저산소성 뇌혈관 손상 제어 기전 규명 (연구책임자)
2016.03-2019.03 [산림청] 융복합기반임산업의신산업화기술개발지원사업 (235,098,920원) 더덕추출물의 지표성분의 심혈관계 작용기전 및 임상중재에 대한 연구 (연구책임자)
2012.05-2015.04 [한국연구재단] 중견연구자지원 핵심공동연구 (606,000,000원) 아로마의 허혈성 뇌손상 억제 효과 및 시냅스 가소성 변화에 관한 연구 (연구책임자)
2010.05-2013.04 [한국연구재단] (이공)일반연구자-신진연구(연구장비지원)(194,527,000원) 염증성 통증모델에서 아로마를 이용한 진통 효능 기전 연구 (연구책임자)
2009.05-2012.04 [한국연구재단] (이공)일반연구자지원-여성과학자 (139,762,000원) 혈관긴장도에 미치는 아로마의 항고혈압 기전에 대한 연구 (연구책임자)
2007.05-2010.02 [한국과학재단] 특정기초연구 (140,216,980원) 아로마의 허혈성 뇌손상 억제 효과 및 시냅스 가소성 변화에 관한 연구 (연구책임자)
2004.03-2006.02 [한국과학재단] 해외PostDoc연수지원사업 (12,437,260원) 노령쥐의 인지기능과 해마 LTD와의 상관관계 연구 (연구책임자)
· Basic Nursing Science Lab I (기초간호과학실습I; 해부생리학실습I)
· Basic Nursing Science II (기초간호과학II; 해부생리학II)
· Basic Nursing Science Lab II (기초간호과학실습II; 해부생리학실습II)
· Basic Nursing Science III (기초간호과학III; 병태생리학)
· Basic Nursing Science IV (기초간호과학IV; 약리학)
· Advanced Basic Nursing Science (상급기초간호과학)
· Seminar in Basic Nursing Science (기초간호과학연구세미나)
· Quantitative Research Methods in Nursing (간호교육연구)
· Seminar in Pathophysiology (병태생리학세미나)
· Basic Research Ethics (연구윤리의기초) [4단계 BK21 기초공통]
· 최인녕(박사후연구원)
· 김유진(박사과정)
· 전하영(석사과정)
· 신지우(석사과정)
· 최선희(석사과정)
· 원혜린(조교)