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고려대학교 교수소개

Knowledge & Innovation

소개

Prof.  William Choi(최혁)

Tel:  02-2626-3302

E-mail: hyuk76@korea.ac.kr

  • Research
  • Publication
  • Professor
  • Lab Members
  • Patents
  • Research

    Professor Choi is interested in and recognized the needs of convergence of medicine, engineering, and life science. Various convergence studies are lively being researched. Most of all, organ chip development using MEMS technology and application of this research to observe disease pattern and look for next-generation therapies through intervertebral disc cells is being studied. Also, micro fluidics based cell mechanism through CFD simulation, rehabilitation robot development of senior patients, and reliability and performance evaluation of medical devices are actively being studied.

     

  • Publication

    Ariticles
     
    Title
    Lucas Camargo, Anna Carolyna Gianlorenço, Kevin Pacheco-Barrios, Elly Pichardo, Valton Costa, Hyuk Choi, Jae-Jun Song, Felipe Fregni. The effects of non-invasive transcutaneous auricular vagus nerve stimulation on resting-state delta oscillation: a randomized, double-blinded, sham-control trial. Scientific Reports. 2025 Oct 3.
    Tae-Won Kim, An-Gi Kim, Min-Ho Hwang, Hyuk Choi. Intervertebral disc spheroids as an in vitro multicellular platform for recapitulating the microenvironment of intervertebral disc degeneration. Biofabrication. 2025 Jun 26.
    Jae-Won Lee, Seoung Min Back, Tae-Won Kim, Hyuk Choi. Development of a microfluidic system with a bearing micropump for applying fluid shear force in an intervertebral disc degeneration model involving mechanical stimulation. 2024 Sep 12.
    Valton Costa, Anna Carolyna Gianlorenço, Maria Fernanda Andrade, Lucas Camargo, Maryela Menacho, Mariana Arias Avila, Kevin Pacheco-Barrios, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Transcutaneous vagus nerve stimulation effects on chronic pain: systematic review and meta-analysis. Pain Reports. 2024 Aug 7.
    Anna Carolyna Gianlorenço, Kevin Pacheco-Barrios, Marianna Daibes, Lucas Camargo, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Age as an effect modifier of the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on heart rate variability in healthy subjects. Journal of Clinical Medicine. 2024 Jul 22.
    Lucas Camargo, Kevin Pacheco-Barrios, Anna Carolyna Gianlorenço, Maryela Menacho, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Evidence of bottom-up homeostatic modulation induced taVNS during emotional and Go/No-Go tasks. Experimental Brain Research. 2024 Jul 4.
    Paulo S. de Melo, Anna C. Gianlorenco, Anna Marduy, Chi K. Kim, Hyuk ChoiJae-Jun Song, Felipe Fregni. A Mechanistic Analysis of the Neural Modulation of the Inflammatory System Through Vagus Nerve Stimulation: A Systematic Review and Meta-analysis. Neuromodulation. 2024 Mar 4.

    Kevin Pacheco-Barrios, Anna Carolyna Gianlorenco, Lucas Camargo, Maria Fernanda Andrade, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Transauricular Vagus Nerve Stimulation (taVNS) enhances CPM in healthy subjects: A randomized controlled trial. Brain Stimulation. 2024 Mar 4.

    Joao Parente, Anna Carolyna Gianlorenco, Ingrid Rebello-Sanchez, Minkyung Kim, Jose Mario Prati, Chi Kyung Kim, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Neural, Anti-Inflammatory, and Clinical Effects of Transauricular Vagus Nerve Stimulation in Major Depressive Disorder: A Systematic Review. Int J Neuropsy. 2024 Mar 1.
    Anna Carolyna Gianlorenco, Kevin Pacheco-Barrios, Lucas Camargo, Elly Pichardo, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Understanding the Effects of Non-Invasive Transauricular Vagus Nerve Stimulation On EEG and HRV. J Vis Exp. 2024 Jan 19.

    Woo-Seok Bang, Inbo Han, Seul-Ah Mun, Jong-Moon Hwang, Sung Hyun Noh, Wonsoo Son, Dae-Chul Cho, Byoung-Joon Kim, Chi Heon Kim, Hyuk Choi, Kyoung-Tae Kim. Electrical stimulation promotes functional recovery after spinal cord injury by activating endogenous spinal cord-derived neural stem/progenitor cell: An in vitro and in vivo study. The Spine Journal. 2023 Oct 14.

    Woo-Keun Kwon, Chang-Min Yoo, Jang Hun Kim, Tae-Won Kim, An-Gi Kim, Min-Ho Hwang, and Hyuk Choi. Role of Human Dural Fibroblasts in the Angiogenic Responses of Human Endothelial Cells: An in Vitro Dural Model and the Application of Lab-on-a-Chip for Edas. Bioengineering & Translational Medicine. 2023 Aug 19.

    Paulo S de Melo, João Parente, Ingrid Rebello-Sanchez, Anna Marduy, Anna Carolyna Gianlorenco, Chi Kyung Kim, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Understanding the Neuroplastic Effects of Auricular Vagus Nerve Stimulation in Animal Models of Stroke: A Systematic Review and Meta-Analysis. Neurorehabil Neural Repair. 2023 Jun 5;15459683231177595.

    Hyeong-Guk Son, Min-Ho Hwang, Sumin Lee, An-Gi Kim, Tae-Won Kim, Joo-Han Kim, Hyuk Choi, Sehoon Jeong. Intervertebral disc organ-on-a-chip: an innovative model to study monocyte extravasation during nucleus pulposus degeneration. Lab Chip. 2023 Jun 13;23(12):2819-2828.

    Angela Yun Kim, Anna Marduy, Paulo S de Melo, Anna Carolyna Gianlorenco, Chi Kyung Kim, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Safety of transcutaneous auricular vagus nerve stimulation (taVNS): a systematic review and meta-analysis. Sci Rep. 2022 Dec 21;12(1):22055. 

    Anna Carolyna L Gianlorenco, Paulo S de Melo, Anna Marduy, Angela Yun Kim, Chi Kyung Kim, Hyuk Choi, Jae-Jun Song, Felipe Fregni. Electroencehalographic patterns in ta VNS: A Systematic Review. Biomedicines. 2022 sep 6 ; 10(9):2208.

    Woo-Keun Kwon, Chang Hwa Ham, Hyuk Choi, Seung Min Baek, Jae Won Lee, Youn-Kwan Park, Hong Joo Moon, Woong Bae Park, Joo Han Kim. Elucidating the effect of mechanical stretch stress on the mechanism of ligamentum flavum hypertrophy: Development of a novel in vitro multi-torsional stretch loading device. PLoS One. 2022 Oct 21;17(10):e0275239. 

    Tae-Won Kim, An-Gi Kim, Kwang-Ho Lee, Min-Ho Hwang, Hyuk Choi. Microfluidic Electroceuticals Platform for Therapeutic Strategies of Intervertebral Disc Degeneration: Effects of Electrical Stimulation on Human Nucleus Pulposus Cells under Inflammatory Conditions. Int J Mol Sci. 2022 Sep 4;23(17):10122.

    Min-Ho Hwang, You Jung Kang, Hyeong-Guk Son, Hansang Cho, Hyuk Choi. Engineered Human Intervertebral Disc Model Inducing Degenerative Microglial Proinflammation. Int J Mol Sci. 2022 Oct 13;23(20):12216. 

    Jae Hee Shin, SeongHyun Park, Hansang Cho, Joo Han Kim & Hyuk Choi. Adipokine Human Resistin Promotes Obesityassociated Inflammatory Intervertebral Disc Degeneration via Pro-inflammatory Cytokine Cascade Activation. Scientific Reports. 2022 May 27;12(1):8936.

    Indong Jun, Na Li, Jaehee Shin, Jaeho Park, Young Jun Kim, Hojeong Jeon, Hyuk ChoiJae-Gu Cho, Byoung Chan Choi, Hyung-Seop Han & Jae-Jun Song. Synergistic stimulation of surface topography and biphasic electric current promotes muscle regeneration. Bioactive MaterialsVolume 11, May 2022, Pages 118-129

    S, M Lee, J, E Lee, Y, K Lee, D, A Yoo, D, B Seon,  D, W Lee, C, B Kim,  H,  Choi & K, H Lee. Thermal-Corrosion-Free Electrode-Integrated Cell Chip for Promotion of Electrically Stimulated Neurite Outgrowth. BioChip Journal 2022 February

    A,G Kim, T, W Kim, W K Kwon, K, H Lee, S,H Jeong, M,H Hwang & H, Choi. Microfluidic Chip with Low Constant-Current Stimulation (LCCS) Platform: Human Nucleus Pulposus Degeneration In Vitro Model for Symptomatic Intervertebral Disc. Micromachines (Basel) 2021 Oct 21;12(11):1291.

    Jae-Woo Cho, Beom-Soo Kim, Do-Hyun Yeo, Eic JuLim, Seungyeob Sakong, Junyoung Lim, SungNam Park, Yong-Hoon Jeong, Tae-Gon Jung, Chang-Wug Oh, Hak Jun Kim, Jong Woong Park, Jong-Keon Oh & Hyuk Choi. 3D-printed, bioactive ceramic scafford with rhBMP-2 in treating critical femoral bone defects in rabbits using the induced membrane technique. JOrthop Res. 2021 Dec; 39(12): 2671-2680

    Hyunjung Lim, Seung Min Back, Min Ho Hwang, Dae-Hee Lee, Jeonghun Nam & Hyuk Choi. Sheathless High-Throughput Circulating Tumor Cell Separation Using Viscoelastic non-Newtonian Fluid. Micromachines (Basel). 2019 Jul 10;10(7):462.

    Hwang, M. H., Son, H.-G., Kim, J. & Choi, H. In vitro model of distinct catabolic and inflammatory response patterns of endothelial cells to intervertebral disc cell degeneration. Scientific Reports, 10, 1-13 (2020).

    Lim, H., Back, S. M., Nam, J. & Choi, H. Acoustic mixing in a dome-shaped chamber-based SAW (DC-SAW) device. Lab on a Chip, 20, 120-125 (2020).

    Hwang, M. H., Lee, J. W., Son, H. G., Kim, J. H., & Choi, H. Effects of photobiomodulation on annulus fibrosus cells derived from degenerative disc disease patients exposed to microvascular endothelial cells conditioned medium. Scientific reports, 10, 1-12 (2020).

    JaeHee Shin, MinHo Hwang, SeungMin Back, HyoGeun Nam, ChangMin Yoo, JeongHun Park, HyeongGuk Son, JaeWon Lee, HyunJung Lim, KwangHo Lee, HongJoo Moon, JooHan Kim, HanSang Cho & Hyuk Choi. Electrical impulse effects on degenerative human annulus fibrosus model to reduce disc pain using micro-electrical impulse-on-a-chip.Scientific reports, 9, 1-11 (2019).

    Min Ho Hwang, Hyeong Guk Son, Jae Won Lee, Chang Min Yoo, Jae Hee Shin, Hyo Geun Nam, Hyun Jung Lim, Seung Min Baek, Jeong Hun Park, Joo Han Kim & Hyuk Choi. 3Photobiomodulation of extracellular matrix enzymes in human nucleus pulposus cells as a potential treatment for intervertebral disk degeneration. Scientific reports, 8, 1-13 (2018).

    Lim, H., Back, S. M., Nam, J. & Choi, H. Determination of red blood cell deformability using centrifugal force in a three-dimensional-printed mini-disk (3D-PMD). PloS one13, e0197619 (2018).

    Min Ho Hwang, Hyeong Guk Son, Jae Won Lee, Chang Min Yoo, Jae Hee Shin,Hyo Geun Nam, Hyun Jung Lim, Seung Min Baek, Jeong Hun Park, Joo Han Kim & Hyuk Choi. Phototherapy suppresses inflammation in human nucleus pulposus cells for intervertebral disc degeneration. Lasers in medical science, 33, 1055-1064 (2018).

    Min Ho Hwang, Dong Hyun Cho, Seung Min Baek, Jae Won Lee, Jeong Hun Park, Chang Min Yoo, Jae Hee Shin, Hyo Geun Nam, Hyeong Guk Son, Hyun Jung Lim, Han Sang Cho, Hong Joo Moon, Joo Han Kim, Jong Kwang Lee & Hyuk Choi. Spine-on-a-chip: Human annulus fibrosus degeneration model for simulating the severity of intervertebral disc degeneration. Biomicrofluidics, 11, 064107 (2017).

    Seung Min Lee, Hang Jin Byeon, Bong Hoon Kim, Jungyup Lee, Ji Yoon Jeong, Joong Hoon Lee, Jin-Hee Moon, Cheolsoo Park, Hyuk Choi, Sang-Hoon Lee & Kwang-Ho Lee. Flexible and implantable capacitive microelectrode for bio-potential acquisition. BioChip Journal, 11, 153-163 (2017).

    Lim, H., Jo, G. E., Kim, K. S., Back, S. M. & Choi, H. Miniaturized thermocycler based on thermoelectric heating for diagnosis of sexually transmitted disease by DNA amplification.Review of Scientific Instruments, 88, 055001 (2017).

    Min Ho Hwang, Kyoung Soo Kim, Chang Min Yoo, Jae Hee Shin, Hyo Geun Nam, Jin Su Jeong, Joo Han Kim, Kwang Ho Lee & Hyuk Choi. Photobiomodulation on human annulus fibrosus cells during the intervertebral disk degeneration: extracellular matrix-modifying enzymes. Lasers in medical science, 31, 767-777 (2016).

    Hyo Geun Nam, Chang Min Yoo, Seoung Min Baek, Han Ki Kim, Jae Hee Shin, Min Ho Hwang, Ga Eun Jo, Kyong Soo Kim, Jae Hwa Cho, Seung Hoon Lee, Ho Chul Kim, Chun Hak Lim, Kyung Sun & Hyuk Choi. Enhancement of mechanical properties and testing of nitinol stents in cerebral aneurysm simulation models. Artificial organs, 39, E213-E226 (2015).

    Min Ho Hwang, Jae Hee Shin, Kyoung Soo Kim, Chang Min Yoo, Ga Eun Jo,Joo Han Kim & Hyuk Choi. Low level light therapy modulates inflammatory mediators secreted by human annulus fibrosus cells during intervertebral disc degeneration in vitro. Photochemistry and photobiology, 91, 403-410 (2015).

    Kwang Ho Lee, Ki Hwa Lee, Jeonghoon Lee, Hyuk Choi, Donghee Lee, Yongdoo Park & Sang-Hoon Lee. Integration of microfluidic chip with biomimetic hydrogel for 3D controlling and monitoring of cell alignment and migration. Journal of Biomedical Materials Research Part A, 102, 1164-1172 (2014).

    Chang, G. U., Jang, T. Y., Kim, K.-S., Choi, H. & Kim, Y. H. Nonspecific hyper-reactivity and localized allergy: cause of discrepancy between skin prick and nasal provocation test.Otolaryngology--Head and Neck Surgery150, 194-200 (2014).

    Joo Han Kim, Hyuk Choi, Min Ji Suh, Jae Hee Shin, Min Ho Hwang, & Heung-Man Lee. Effect of biphasic electrical current stimulation on IL-1β–stimulated annulus fibrosus cells using in vitro microcurrent generating chamber system. Spine, 38, E1368-E1376 (2013).

    Ho Chul Kim, Hyuk Choi, Seung Oh Jin, Jae Jo Lee, Kyoung-Won Nam, In-Young Kim, Ki Chang Nam, Hyung Joo Park, Kwang Ho Lee & Min Gi Kim. New computerized indices for quantitative evaluation of depression and asymmetry in patients with chest wall deformities. Artificial organs, 37, 712-718 (2013).

    Won, S. J., Kim, B. J., Park, K. S., Yoon, J. S. & Choi, H. Reference values for nerve ultrasonography in the upper extremity.Muscle & nerve, 47, 864-871 (2013).

    Park, I.-H., Hong, S.-M., Choi, H., Chang, H. & Lee, H.-M. Sclerosing polycystic adenosis of the nasal septum: the risk of misdiagnosis.Clinical and Experimental Otorhinolaryngology6, 107 (2013).

    Heung-Man Lee, Man Sik Park, Il Ho Park, Seung Hoon Lee, Seong Keon Lee, Kyu-Sung Kim & Hyuk Choi. A comparative pilot study of symptom improvement before and after phototherapy in Korean patients with perennial allergic rhinitis. Photochemistry and Photobiology, 89, 751-757 (2013).

    Tae Nyun Kim, Man Sik Park, Kang Il Lim, Hae Yoon Choi, Sae Jeong Yang, Hye Jin Yoo, Hyun Joo Kang, Wook Song, Hyuk Choi, Sei Hyun Baik, Dong Seop Choi & Kyung Mook Choi. Relationships between sarcopenic obesity and insulin resistance, inflammation, and vitamin Dstatus: the Korean Sarcopenic Obesity Study. Clinical endocrinology, 78, 525-532 (2013).

    Dong Bin Kim, Hyuk Choi, Sang Min Joo, Han Ki Kim, Jae Hee Shin, Min Ho Hwang, Jaesoon Choi, Dong-Gon Kim, Kwang Ho Lee, Chun Hak Lim, Sun Kook Yoo, Heung-Man Lee & Kyung Sun. A comparative reliability and performance study of different stent designs in terms of mechanical properties: foreshortening, recoil, radial force, and flexibility. Artificial organs, 37, 368-379 (2013).

    Hye Gyo Chung, Soohyun A Myung, Ho Sung Son, Yun Hee Kim, Jin Namgung, Mi La Cho, Hyuk Choi & Choon Hak Lim. In vitro effect of clinical propofol concentrations on platelet aggregation. Artificial organs, 37, E51-E55 (2013).

    Hyuk Choi, Man Sik Park, Bonghyun Nam, Jungbok Lee, Eunhi Kim & Heung-Man Lee. Palm surface area database and estimation formula in Korean children using the alginate method. Applied ergonomics, 42, 873-882 (2011).

    Seung-Joon Song, Jaesoon Choi, Yong-Doo Park, Soyoung Hong, Jung Joo Lee, Chi Bum Ahn, Hyuk Choi & Kyung Sun. Sodium alginate hydrogel‐based bioprinting using a novel multinozzle bioprinting system. Artificial organs, 35, 1132-1136 (2011).

    Choi, H., Park, M. S. & Lee, H.-M. Hand surface area as a percentage of body surface area in Asian children: A pilot study.Burns37, 1062-1066 (2011).

    Hyuk Choi, Heung-Man Lee, Kyoung Won Nam, Jaesoon Choi, Jung-Joo Lee, Ho Chul Kim, Seung Joon Song, Chi Bum Ahn, Ho Sung Son, Choon Hak Lim, Kuk Hui Son, Yong Doo Park, Gi Seok Jeong & Kyung Sun. A Durability Study of a Paracorporeal Pulsatile Electro‐Mechanical Pneumatic Biventricular Assist Device. Artificial organs, 35, 614-624 (2011).

    Choi, H., Park, I.-H., Yoon, H. G. & Lee, H.-M. Comparison of nasal sound spectral analysis and peak nasal inspiratory flow before and after decongestion in patients with nasal obstruction. Annals of Otology, Rhinology & Laryngology,120, 391-396 (2011).

    Choi, H., Cho, J.-S., Park, I. H., Yoon, H. G. & Lee, H.-M. Effects of microelectrical current on migration of nasal fibroblasts. American journal of rhinology & allergy, 25, 157-162 (2011).

    Il-Ho Park, Seong Woong Choi, Hyuk Choi, Tae Hoon Kim, Seung Hoon Lee, Sang Hag Lee & Heung-Man Lee. Increased expression of a disintegrin and metalloprotease 8 in allergic rhinitis. American journal of rhinology & allergy, 25, e107-e111 (2011).

    Choi, H., Park, I.-H., Geun, H. & Lee, H.-M. Diagnostic accuracy evaluation of nasal sound spectral analysis compared with peak nasal inspiratory flow in nasal septal deviation. American journal of rhinology & allergy, 25, e86-e89 (2011).

    Choi, H., Park, I.-H., Yoon, H. G. & Lee, H.-M. Wireless patient monitoring system for patients with nasal obstruction. Telemedicine and e-Health, 17, 46-49 (2011).

    Kyu Sung Hwang, Il-Ho Park, Hyuk Choi, Seung Hoon Lee, Sang Hag Lee & Heung-Man Lee. Increased expression of angiogenin in nasal polyps. American journal of rhinology & allergy, 25, e23-e26 (2011).

    Dae-Hyung Kim, Il-Ho Park, Jung-Sun Cho, You-Mi Lee, Hyuk Choi & Heung-Man Lee. Alterations of vasoactive intestinal polypeptide receptors in allergic rhinitis. American journal of rhinology & allergy, 25, e44-e47 (2011).

     

  • Profile

    Professional Career
    Professional Career
    Period Experience

    2020. 08. 01 ~

     Standardization Committee Chairperson, 

    Organoid Society

    2018. 09. 01 ~

    Professor, Department of Biomedical engineering, 

    Korea University College of Medicine, Seoul, Korea

    2018. 01. 01 ~

    Director, 

    The Korean BioChip Society

    2018. 01. 01 ~

    Member of next generation medical device 100 Project 

    2017. 07. 01 ~

    Council of the Reviewer,

    Korea Health Industry Development Institute

    2017. 06. 01 ~

    Member of the Committee,

    Ministry of Food and Drug Safety of Korea (KFDA)

    2016. 09. 01 ~

    Clinic of the committee of special talent,

    National Institute of Food and Drug Safety Evaluation

    2016. 03. 01 ~

    International Cooperation team of the assistant manager, 

    National Institute of Food and Drug Safety Evaluation

    2016. 02. 01 ~

    Member of the Steering Committee,

    Korea Testing Laboratory 

    2014. 03. 01 ~

    Member of the Science Committee,

    Korea Agency Institutional Review Board (KAIRB)

    2014. 09. 01 ~ 2018. 08. 31

    Associate Professor, Department of Biomedical engineering, 

    Korea University College of Medicine, Seoul, Korea

    2011. 09. 01 ~ 2014. 08. 31

    Assistant Professor, Department of Biomedical engineering, 

    Korea University College of Medicine, Seoul, Korea

    2014. 07. 07 ~

    Member of the Committee,

    Korea association of Institutional Review Board

    2011. 11. 01 ~

    Ministry of Health and Welfare New Excellent Technology,

    expert member

    2011. 05. 14 ~

    Member of the Committee,

    Ministry of Food and Drug Safety of Korea (KFDA)

    2011. 03. 24 ~

    Evaluation Member of the Committee, 

    Convergence science association of National Research Foundation of Korea

    2011. 02. 16 ~

    Evaluation Member of the Committee,

    (DMIC)

    2010. 08. 05 ~ 2011. 08. 31

    Director,

    Research Institute of Micro current

    2010. 09 ~

    Member of the Committee, 

    Technology Innovation Program for Knowledge Economy by the Ministry of Knowledge Economy

    2009. 09. 10 ~

    Member of the Committee,

    Institutional Review Board of Korea University Guro Hospital

    2009. 09. 01 ~

    Vice director,

    Medical Device Clinical Trial Center (Korea University)

    2008. 04. 01 ~ 2009. 08. 31

    Assistant teacher, Department of Biomedical engineering, 

    Korea University College of Medicine, Seoul, Korea

    2007. 09. 01 ~ 2008. 03. 31

    Post doctor, Department of Biomedical engineering,

    Korea University College of Medicine, Seoul, Korea

    2007. 03. 01 ~ 2007. 08. 31

    Researcher, Department of Biomedical engineering,

    Korea University College of Medicine, Seoul, Korea

     

  • Lab Members

    Current Members
    Lab Members
    Jae Won Lee
    Status M.S. & Ph.D Integrated Course
    Major

    Biomedical Engineering

    (B.S. - Biomedical Engineering)

    E-mail dl2wo1dnjs@korea.ac.kr
    Tae Won Kim
    Status M.S. & Ph.D Integrated Course
    Major

    Biomedical Engineering

    (B.S. - Biotechnology)

    E-mail tw626@naver.com
    An Gi Kim
    Status M.S. & Ph.D Integrated Course
    Major

    Biomedical Engineering

    (B.S. - Electronic Engineering)

    E-mail 16_151_832@korea.ac.kr
    Chae Won Shin
    Status M.S. & Ph.D Integrated Course
    Major

    Biomedical Engineering

    (B.S. - Biotechnology)

    E-mail codnjs000326@korea.ac.kr
    Alumni
    Alumni
    Ga Eun Jo
    Degree M.S.
    Major Biomedical Engineering
    E-mail gabi1128@korea.ac.kr
    Kyoung Soo Kim
    Degree M.S.
    Major Biomedical Engineering
    E-mail dksrudrltm@nate.com
    Hyun Jung Lim
    Degree Ph.D.
    Major Biomedical Engineering
    E-mail hyunjunglim.email@gmail.com
    Jae Hee Shin
    Degree Ph.D.
    Major Biomedical Engineering
    E-mail wogmltls@korea.ac.kr
    Hyo Geun Nam
    Degree Ph.D.
    Major Biomedical Engineering
    E-mail namhyogen@naver.com
    Hyeong Guk Son
    Degree Ph.D.
    Major

    Biomedical Engineering

    E-mail kuki331@korea.ac.kr
    Chang Min Yoo
    Degree Ph.D.
    Major Biomedical Engineering
    E-mail changminyoo@korea.ac.kr
    Jae Yeon Koh
    Degree M.S.
    Major Biomedical Engineering
    E-mail gjae9900@naver.com
    Seung Min Back
    Degree Ph.D.
    Major Biomedical Engineering
    E-mail seung5580@naver.com
    Min Ho Hwang
    Degree Ph.D.
    Major Biomedical Engineering
    E-mail cannone86@korea.ac.kr

     

  • Patents

    Patents
    Professional Career
    No.

    Title

    Applicant

    Inventor

    1

    미주신경 자극 장치 및 이의 제어 방법

    (Vagus Nerve Stimulator Device and Control Method of the Same)

    Korea University Research

    and Business Foundation

    10-2025-0085308 (2025.06.26.)

    Choi Hyuk

    2

    무선형 웨어러블 신경자극장치

    (Over-Ear Stimulation Apparatus for Nerve)

    Korea University Research

    and Business Foundation

    10-2023-0098449 (2023.07.27.)

    Choi Hyuk

    3

    생체신호 측정에 따른 증상 정도를 반영한 미주신경에 대한

    전기자극 인가 방법 및 전기자극 인가 장치

    Korea University Research

    and Business Foundation

    PCT/KR2023/006863 (2023.05.19.)

    Song Jae-Jun, Choi Hyuk

    4

    임피던스 측정을 반영한 미주신경에 대한 전기자극 인가 방법 및 미주신경 자극 장치

    Korea University Research

    and Business Foundation

    PCT/KR2023/006862 (2023.05.19.)

    Song Jae-Jun, Choi Hyuk

    5

    생체 신호를 통한 사용자 상태 및 자극 민감도를 반영한 미주신경에 대한

    전기자극 인가 방법 및 미주신경 자극 장치

    Korea University Research

    and Business Foundation

    PCT/KR2023/006860 (2023.01.25.)

    Song Jae-Jun, Choi Hyuk

    6

    뇌 신경 모델링 장치

    (Apparatus for Brain Neural Modeling)

    Korea University Research

    and Business Foundation

     10-2691068(2024.07.29.)

    Choi Hyuk, Lee Jae-Won,

    Won Ki Yoon, Hwang Min Ho

    7

    임플란트에 포함된 재료의 생체 적합성을 평가하기 위한

    생체 모사 환경을 제공하는 바이오 칩 장치

    (Biochip Device Providing a Biomimetic Environment for Evaluating the Biocompatibility of Materials Included in Implant)

    Korea University Research

    and Business Foundation

    10-2023-0005567 (2023.01.13.)

    Choi Hyuk, Kim An-Gi,

    Back Seung-min, Lee Jae-Won,

    Hwang Min Ho, Shim Ji-Suk,

    Moon Hyun-Kyung, Ryu Jae Jun,

    Won Jong-Eun

    8

    Electrophysiology Testing Platform Using a Three-Dimensional Cell Chip

    Korea University Research

    and Business Foundation

    10-2021-0157489

    Choi Hyuk, Lee Jae-Won,

    Hwang Min Ho, Kim An-Gi 

    9

    Electromagnetic Field Stimulation Apparatus And Method And Apparatus For Cell Culture Chip

    Korea University Research

    and Business Foundation

    10-2021-0141029

    Choi Hyuk, Lee Jae-Won,

    Hwang Min Ho, Yoo Chang-Min

    10

    Cell Photostimulation Device

    Korea University Research

    and Business Foundation

    10-2021-0087229

    Choi Hyuk, Hwang Min Ho,

    Kim An-Gi , Kim Taewon,

    Koh Jae-Yeon 

    11

    Method And Apparatus For Applying Electrical Stimulation To Microfluidic Cells

    Korea University Research

    and Business Foundation

    10-2021-0043308

    Choi Hyuk, Hwang Min Ho,

    Kim An-Gi 

    12

     Method And Apparatus For Electrical Stimulation Applying Electrical Stimulation To The Skin

    Korea University Research

    and Business Foundation

    10-2021-0042855

    Choi Hyuk, Lee Jae-Won

    13

    Method And Apparatus For Complex Stimulus Output For Skin

    Korea University Research

    and Business Foundation

    10-2021-0035965

    Choi Hyuk, Lee Jae-Won

    14

    Chamber Chip, Microfludix Mixing Device Including The Chamber Chip And Method Of Manufcturing The Microfluidic Mixing Device

    Korea University Research

    and Business Foundation

    10-2019-0137219

    Choi Hyuk, Nam Jeonghun,

    Lim Hyunjung

    15

    Portable Catheter Inserting Device

    Korea University Research

    and Business Foundation

    10-2098766

    Choi Hyuk, Yoon Joon Shik,

    Kang Seok

    16

    Apparatus for providing complex stimulation to cells

    Korea University Research

    and Business Foundation

    10-2085820

    Choi Hyuk, Kim Joo-han,

    Shin Jae-hee, Hwang Min-ho,

    Back Seung-min, Lee Jae-won

    17

    A stimulated response device of intervertebral disc cells

    Korea University Research

    and Business Foundation

    10-1970415

    Choi Hyuk, Hwang Min-ho,

    Kim Joo-han

    18

    Three-Dimensional Cell Culture Chip

    Korea University Research

    and Business Foundation

    10-1965076

    Choi Hyuk, Hwang Min-ho,

    Nam Hyo-geun

    19

    Secretory protein detection chip And Secretory protein detection device for Disc disease research

    Korea University Research

    and Business Foundation

    10-1916568

    Choi Hyuk, Hwang Min-ho,

    Nam Hyo-geun

    20

    Intervertebral disc cell co-culture device for the study of intervertebral disc pain control mechanism

    Korea University Research

    and Business Foundation

    10-1916567

    Choi Hyuk, Hwang Min-ho,

    Nam Hyo-geun

    21

    Inflammation model simulated chip

    Korea University Research

    and Business Foundation

    10-2017-0001210

    Choi Hyuk, Hwang Min-ho,

    Nam Hyo-geun

    22

    Reaction Research Chip For Research Of Rwaction Between Different Kind Of Cells Which Compose Tissue

    Korea University Research

    and Business Foundation

    10-1848201

    Choi Hyuk, Hwang Min-ho,

    Nam Hyo-geun

    23

    Cell Culture Microfluidic Chip And Microfluidic Chip Device For Observing Pathological Mechanisms

    Korea University Research

    and Business Foundation

    10-1782263

    Choi Hyuk, Hwang Min-ho,

    Park Jeong-hun

    24

    Diagnostic Kit For Diagnosing Vaginitis

    Korea University Research

    and Business Foundation

    10-2015-0102826

    Choi Hyuk, Jo Ga-eun

    25

    Method For Measuring Traction Power Of Annulus Fibrosus Cell When Infammation Of Generating Disc Is Expressed

    Korea University Research

    and Business Foundation

    10-1725601

    Choi Hyuk, Park Yong-doo,

    Hwang Min-ho

    26

    Dual Mode BIO-Feed Back Rehabilitation Treatment Device

    Korea University Research

    and Business Foundation

    10-1592089

    Choi Hyuk, Kim Kyoung-soo,

    Back Seung-min

    27

    Method For Generating Disc Cell Inflammatory Model And Method For Determining Optimum Laser Wavelength For Disc Cell Inflammatory Treatment Using The Same

    Korea University Research

    and Business Foundation

    10-1581589

    Choi Hyuk, Hwang Min-ho,

    Kim Kyoung-soo

    28

    High Frequency Treatment Apparatus Having Cooling Function

    Korea University Research

    and Business Foundation

    10-2015-0090221

    Choi Hyuk, Hwang Min-ho

    29

    High Frequency Treatment Apparatus Having Spark-Prevention Function 

    Korea University Research

    and Business Foundation

    10-2015-0090484

    Choi Hyuk, Hwang Min-ho

    30

    Wound Healing Apparatus Negative Pressure And Micro Current

    Korea University Research

    and Business Foundation

    10-1528401

    Choi Hyuk

    31

    Bacterial Vaginosis Test Chip, Apparatus For Detecting Bacterial Vaginosis And Detection Method Using Thereof

    Korea University Research

    and Business Foundation

    10-1528433

    Choi Hyuk, Jo Ga-eun

    32

    Gradient Microfluidic Chip Device

    Korea University Research

    and Business Foundation

    10-1528429

    Choi Hyuk, Hwang Min-ho

    33

    Portable Skin Care Device

    Korea University Research

    and Business Foundation

    10-2015-0003115

    Choi Hyuk

    34

    Catheter Inserting Apparatus For Urinary System

    Korea University Research

    and Business Foundation

    10-1374492

    Choi Hyuk, Yoon Joon-shik

    35

    Needle Guide For Remedying Otits Media

    Korea University Research

    and Business Foundation

    10-1260676

    Lee Heung-man, Choi Hyuk,

    Park Il-ho

    36

    Hemostatic Packing

    Korea University Research

    and Business Foundation

    10-1310625

    Lee Heung-man, Choi Hyuk

    37

    Needle Holder For Transseptal Suturing

    Korea University Research

    and Business Foundation

    10-2011-0033222

    Lee Heung-man, Choi Hyuk

    38

    Medicine Dispenser And Medicine Supply System Using The Same

    Korea University Research

    and Business Foundation

    10-1175210

    Choi Hyuk

    39

    Apparatus For Increasing Alveolar Bone 

    Korea University Research

    and Business Foundation

    10-1655109

    Choi Hyuk

    40

    Portable Catheter Inserting Device

    Korea University Research

    and Business Foundation

    10-2098766

    Choi Hyuk

    41

    Cell Incubation Apparatus Using Micro-current Occurrence

    Korea University Research

    and Business Foundation

    10-1239731

    Lee Heung-man, Choi Hyuk

    42

    Non-Invasive Nasal Sound Analyzing Apparutus, Non-Invasive Nasal Sound Analyzing System Available Of Wireless Data Transmission, Non-Invasive Nasal Sound Analyzing Method And Medium Recorded The Same Methed

    Korea University Research

    and Business Foundation

    10-1182762

    Lee Heung-man, Choi Hyuk