소개
Prof.이지원
Office: New Engineering Hall #715
Tel:02-3290-3304
E-mail:leejw@korea.ac.kr
- About Professor
- Curriculum Vitae
- Publication
- Lab Members
Profile
Professor. Jeewon Lee
- Office: New Engineering Hall #715
- E-mail: leejw@korea.ac.kr
- Phone: +82-2-3290-3304 / +82-2-3290-3721
- Fax: +82-2-926-6102
- Lab: Laboratory of Biomolecular Engineering
Curriculum Vitae
Education
- B.S., Dept. Chemical Engineering, Seoul National University (1985)
- Ph.D., Dept. Biochemical Engineering, Illinois Institute of Technology (1992)
Professional Experiences
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2020. 01. 01 - 2020. 12. 31: 한국생물공학회(KSBB) 회장2019. 01. 01 - 2020. 12. 31: 한국과학기술단체총연합회 대의원2019. 01. 01 - 2020. 12. 31: 한국생물공학회(KSBB) 수석부회장2019. 10. 01 - 2020. 12. 31: 세계미생물학회연합 (International Union of Microbiological Societies/IUMS) 총회 조직위원회 자문위원
- 2002. 03. 01 - 현재: 고려대학교 화공생명공학과 부교수, 교수
- 2017. 01. 01 – 현재: 한국공학한림원 일반회원, 정회원
- 2013. 02. 01 - 2015.01.31: 고려대학교 화공생명공학과 학과장
- 2014. 05. 01 - 현재 : 한국연구재단 기초연구본부 전문위원
- 2015. 12. 01 - 현재: 삼성 미래기술 육성사업 연구책임자
- 2012. 05. 01 - 현재: 중견도약연구사업(한국연구재단) 연구책임자
- 2008. 08. 01 - 2010. 7. 31: 고려대학교 공과대학 부학장
- 2010. 09. 01 - 2011. 8. 31: 미국 MIT 방문교수
- 2007. 06. 01 - 2012. 5. 31: 국가지정연구실(NRL) 연구책임자
- 1998. 01. 01 - 2002. 2. 28: 한국생명공학연구원(KRIBB) 선임연구원
- 1994. 03. 01 - 1997. 12. 31: 한효과학기술원 생물공정실장
- 1993. 01. 01 - 1994. 01. 01: 미국 Institute of Gas Technology Post-doctoral research fellow
- 1984. 12 - 1986. 05: (주)동양화학 중앙연구소 공정개발실 연구원
학회활동
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한국생물공학회(KSBB) 회장 (2020. 01. 01 - 2020. 12. 31)한국생물공학회 수석부회장 (2019. 01. 01.- 2019. 12. 31)세계미생물학회연합 (International Union of Microbiological Societies/IUMS) 총회 조직위원회 자문위원 (2019. 10. 01 - 2020. 12. 31)
- Bioprocess. Technol. Senior Editor (2013. 02 - 현재)
- Biotechnol. Bioprocess Eng. Associate Editor, Editor (1998. 01 - 현재)
- J. Ind. Eng. Chem. Editor (2003. 01 - 2004. 12)
- J. Microbiol. Biotechnol. Editor (2001. 07 - 2004. 06)
- 한국생물공학회 바이오칩 및 나노바이오공학 부문위원회 위원장 (2014. 01. 01 - 현재)
- 한국생물공학회 총무이사 (2013. 01. 01- 12. 31)
- 한국생물공학회 기획이사 (2012. 01. 01-12. 31)
- 한국생물공학회 학술이사 (2009. 01. 01-12. 31)
- 한국생물공학회 국제협력이사 (2008. 01. 01-12. 31)
- 한국생물공학회 기획이사 (2004. 01. 01-12. 31)
- 한국화학공학회 국제이사 (2009. 01. 01-12. 31)
- 한국화학공학회 생물화공부문위원회 감사 (2008. 01. 01 - 2008. 12. 31)
- 한국화학공학회 생물화공부문위원회 총무간사 (2007. 01. 01 - 2007. 12. 31)
- 한국화학공학회 생물화공부문위원회 기획간사 (2005. 01 - 2005. 12)
- 한국화학공학회 생물화공부문위원회 편집간사 (2002. 01 - 2003. 12)
- 한국미생물ㆍ생명공학회 생물공학부문위원회 위원장 (2006. 01-2008. 12)
- 13th Symposium of YABEC (Young Asian Biochemical Engineers' Community) (2007.10.20-22) 조직위원회 총무(Secretary General)
- 7th Asia-Pacific Biochemical Engineering Conference (2005.05.15-19) 조직위원회 편집위원
수상실적
- 2022년도 과학·정보통신인의 날 기념식 과학기술훈장 진보장 (정부 포상)
- 2022년도 석탑기술상 (2022 / 고려대학교 총장 표창)
- 2021년도 한국생물공학회 학술대상
- 제54회 과학의 날 과학기술정보통신부 장관 표창
- 2021년도 한국생물공학회 학술진흥상
- 2020년도 석탑기술상 (2020 / 고려대학교 총장 표창)
- 2014년도 올해의 10대 과학기술 뉴스 선정 (한국과학기술총연합회)
- 2013년도 기초연구 우수성과 (2013. 10. 16. / 한국연구재단 이사장 표창)
- 2012년도 국가연구개발 우수성과 (2013. 08. 28. / 미래창조과학부 장관 표창)
- 2010년도 기초연구 우수성과 (2010. 10. 26. / 교육과학기술부 장관 표창)
- 2010, 2012, 2014, 2015, 2016, 2017, 2019년도 우수강의상 (고려대학교 총장 표창)
- 2009년도 석탑강의상 (2010. 05. 05. / 고려대학교 총장 표창
Publication
대표 연구실적
- 1. Biological conversion of methane to methanol through genetic reassembly of native catalytic domains, Nature Catalysis 2, 342-353 (2019) Hyun Jin Kim, June Huh, Young Wan Kwon, Donghyun Park, Yeonhwa Yu, YoungEun Jang, Bo-Ram Lee, Eunji Jo, Eun Jung Lee, Yunseok Heo, Weontae lee, Jeewon Lee*
- 2. A highly sensitive and selective diagnostic assay based on virus nanoparticles, Nature Nanotechnology 29, 1701146 (2009) Jin-Seung Park, Moon Kyu Cho, Eun Jung Lee, Keum-Young Ahn, Kyung Eun Lee, Jae Hun Jung, Yunjung Cho, Sung-Sik Han, Young Keun Kim, Jeewon Lee*
- 3. A rationally designed miniature of soluble methane monooxygenase enables rapid and high-yield methanol production in Escherichia coli, Nature Communications 15(1), 4399 (2024) Yeonhwa Yu, Yongfan Shi, YoungWan Kwon, Yoobin Choi, Yusik Kim, Jeong-Geol Na, June Huh, Jeewon Lee*
- 4. Superparamagnetic Gold Nanoparticles Synthesized on Protein Particle Scaffolds for Cancer Theragnosis, Advanced Materials 29, 1701146 (2017) Koo Chul Kwon, Eunji Jo, Young-Wan Kwon, Boram Lee, Ju Hee Ryu, Eun Jung Lee, Kwangmeyung Kim, Jeewon Lee*
- 5. Proteinticle/Gold Core/Shell Nanoparticles for Targeted Cancer Therapy without Nanotoxicity, Advanced Materials 26, 6436-6441 (2014) Koo Chul Kwon, Ju Hee Ryu, Jong-Hwan Lee, Eun Jung Lee, Ick Chan Kwon, Kwangmeyung Kim, Jeewon Lee*
- 6. A novel bioassay platform using ferritin-based nanoprobe hydrogel, Advanced Materials 24 4739-4744 (2012) Eun Jung Lee, Keum-Young Ahn, Jong-Hwan Lee, Jin-Seung Park, Jong-Am Song, Sang Jun Sim, Eun Bong Lee, Young Joo Cha, Jeewon Lee*
- 7. Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells, Advanced Functional Materials 25, 1279-1286 (2015) Eun Jung Lee, So Jin Lee, Yoon-Sik Kang, Ju Hee Ryu, Koo Chul Kwon, Eunji Jo, Ji Young Yhee, Ick Chan Kwon, Kwangmeyung Kim, Jeewon Lee*
- 8. A Three-Dimensional and Sensitive Bioassay Based on Nanostructured Quartz Combined with Viral Nanoparticles, Advanced Functional Materials 20, 2004-2009 (2015) Jong-Hwan Lee, Jung Suk Kim, Jin-Seung Park, Wonbae Lee, Kyung Eun Lee, Sung-Sik Han, Kyu Back Lee*, Jeewon Lee*
- 9. Proteinticle Engineering for Accurate 3D Diagnosis, ACS NANO 7, 10879-10886 (2013) Jong-Hwan Lee, Hyuk Seong Seo, Jong Am Song, Koo Chul Kwon, Eun Jung Lee, Ho Jin Kim, Eun Bong Lee, Young Joo Cha, Jeewon Lee*
- 10. Nonimmunogenetic Viral Capsid Carrier with Cancer Targeting Activity, Advanced Science 5, 1800494 (2018) Bo-Ram Lee, Eunji Jo, Hong Yeol Yoon, Chul Joo Yoon, Hyo-Jung Lee, Koo Chul Kwon, Tae Woo Kim, Jeewon Lee*
- 11. Genetic Assembly of Double-Layered Fluorescent Protein Nanoparticles for Cancer Targeting and Imaging, Advanced Science 4, 1600471 (2017) Seong-Eun Kim, Sung Duk Jo, Koo Chul Kwon, You-Yeon Won, Jeewon Lee*
- 12. A Platinum-Protein hybrid nanostructure enables both targeted cancer theragnosis and platinum clearance. Chemical Engineering Journal 494: 152957 (2024) Sojin Jeong, Young Wan Kwon, Yewon Lee, Tai-Kyong Song, Jeewon Lee*
- 13. Tumor-specific release of copper-incorporated diethyldithio-carbamate from an optimized apoferritin scaffold enables both potent and safe anti-cancer therapy. Chemical Engineering Journal 473: 145176 (2023) Ok Jeong Moon, Chul Joo Yoon, Jun Soo Lee, Hye Hyun Kim, Yong Hwan Seol, and Jeewon Lee*
- 14. Engineered protein nanoparticles for in vivo tumor detection. Biomaterials 35, 6422-6429 (2014) Keum-Young Ahn, Ho Kyung Ko, Bo-Ram Lee, Eun Jung Lee, Jong-Hwan Lee, Youngro Byun, Ick Chan Kwon, Kwangmeyung Kim*, Jeewon Lee*
- 15. Terminal Tryptophan-Directed Anisotropic Self-Assembly for Precise Protein Nanostructure Regulation, Small 21, 2408977 (2025) Young Eun Jang, June Huh, Yoobin Choi, Yusik Kim, Jeewon Lee*
- 16. Enhanced in vivo tumor detection by active tumor cell targeting using multiple tumor receptor-binding peptides presented on genetically engineered human ferritin nanoparticles, Small 12, 4241-4253 (2016) Koo Chul Kwon , Ho Kyung Ko , Jiyun Lee , Eun Jung Lee , Kwangmeyung Kim*, Jeewon Lee*
SCI Journal
- 1. Young Eun Jang, June Huh, Yoobin Choi, Yusik Kim, and Jeewon Lee* (2025) Terminal Tryptophan-Directed Anisotropic Self-Assembly for Precise Protein Nanostructure Regulation. Small, 21: 2408977
- 2. Sojin Jeong, Young Wan Kwon, Yewon Lee, Tai-Kyong Song, Jeewon Lee* (2024) A Platinum-Protein hybrid nanostructure enables both targeted cancer theragnosis and platinum clearance. Chemical Engineering Journal 494: 152957.
- 3. Yeonhwa Yu, Yongfan Shi, Young Wan Kwon, Yoobin Choi, Yusik Kim, Jeong-Geol Na, June Huh, Jeewon Lee* (2024) A rationally designed miniature of soluble methane monooxygenase enables rapid and high-yield methanol production in Escherichia coli. Nat. Commun. 15(1): 4399.
- 4. Jeongsoo Kim, Tae-Jin Kim, Sehyun Chae, Hyojeong Ha, Yejin Park, Sunghee Park, Chul Joo Yoon, Seon Ah Lim, Hyemin Lee, Jiyoung Kim, Jungwon Kim, Kyungtaek Im, Kyunghye Lee, Jeongmin Kim, Daham Kim, Eunju Lee, Min Hwa Shin, Serk In Park, Inmoo Rhee, Keehoon Jung, Jeewon Lee, Keun Hwa Lee*, Daehee Hwang*, and Kyung-Mi Lee* (2024) Targeted deletion of CD244 on monocytes promotes differentiation into anti-tumorigenic macrophages and potentiates PD-L1 blockade in melanoma. Molecular cancer. 23(1); 45.
- 5. Ok Jeong Moon, Chul Joo Yoon, Jun Soo Lee, Hye Hyun Kim, Yong Hwan Seol, and Jeewon Lee* (2023) Tumor-specific release of copper-incorporated diethyldithio- carbamate from an optimized apoferritin scaffold enables both potent and safe anti-cancer therapy. Chemical Engineering Journal 473: 145176.
- 6. Hye Hyun Kim, Ok Jeong Moon, Yong Hwan Seol, Jeewon Lee* (2023) A simple urine test by 3D-plus-3D immunoassay guides precise in vitro cancer diagnosis. Bioengineering & Translational Medicine 8(3): e10489.
- 7. Ji Sung Cho, Hye Ji Oh, Young Eun Jang, Hyun Jin Kim, Areum Kim, Jong-Am Song, Eun Jung Lee*, Jeewon Lee* (2022) Synthetic propeptide design to enhance the secretion of heterologous proteins by Saccharomyces cerevisiae. Microbiology Open 11(3): e1300.
- 8. Ok Jeong Moon, Chul Joo Yoon, Bo-Ram Lee, Jeewon Lee* (2022) An Optimally Fabricated Platform Guides Cancer-Specific Activation of Chemotherapeutic Drugs and Toxicity-Free Cancer Treatment Advanced Healthcare Materials 11(15): 2200765.
- 9. Yunseok Heo, Hyeongseop Jeong, Youngki Yoo, Ji-Hye Yun, Bumhan Ryu, Young-je Cha, Bo-Ram Lee, Ye-Eun Jeon, Jongmin Kim, Sojin Jeong, Eunji Jo, Jae-Sung Woo, Jeewon Lee*, Hyun-Soo Cho*, and Weontae Lee* (2021) Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid. Int. J. Mol. Sci. 22(17): 9140.
- 10. W. Ahn, J.H. Lee, S.R. Kim*, J. Lee* & E.J. Lee* (2021) Designed Protein- and Peptide-based Hydrogels for Biomedical Sciences, J. Mater. Chem. B, 9(8): 1919-1940 Front cover
- 11. Jae-Hwan Oh, Jung-Hyuk Kwon, Hye-Hyun Kim, and Jeewon Lee* (2021) One-step-immunoassay of procalcitonin enables rapid and accurate diagnosis of bacterial infection. RSC Advances 11(35): 21375-21383.
- 12.Bo-Ram Lee, Hyo-Jung Lee, June Huh, Chul Joo Yoon, Se Jin Oh, Kwon-Ho Song, Sojin Jeong, Beom Soo Shin, Ji Hoon Jeong, Tae Woo Kim and Jeewon Lee* (2021) Human ferritin platform and its optimized structures to enhance anti-cancer immunity. Advanced Therapeutics 4(2): 2000208.
- 13. Yu, Yeonhwa; Jung, Euiyoung; Kim, Hyun Jin; Cho, Ahyoung; Kim, Jinheung; Yu, Taekyung; Lee, Jeewon* (2020) Protein Particles Decorated with Pd Nanoparticles for the Catalytic Reduction of p-Nitrophenol to p-Aminophenol. ACS Applied Nano Materials 3(10): 10487-10496.
- 14. J-H. Kwon, H-H. Kim, H-B. Cho, Y.J. Cha and J. Lee* (2019) Viral antigen nanoparticles for discriminated and quantitative detection of different subtypes of anti-virus immunoglobulins. Nanoscale 11(39): 18282-18289.
- 15. Hyun Jin Kim, June Huh, Young Wan Kwon, Donghyun Park, Yeonhwa Yu, Young Eun Jang, Bo-Ram Lee, Eunji Jo, Eun Jung Lee, Yunseok Heo, Weontae Lee, and Jeewon Lee* (2019) Biological conversion of methane to methanol through genetic reassembly of native catalytic domains. Nat. Catal. 2: 342–353.
- 16. Bo-Ram Lee, Eunji Jo, Hong Yeol Yoon, Chul Joo Yoon, Hyo-Jung Lee, Koo Chul Kwon, Tae Woo Kim, and Jeewon Lee* (2018) Non-immunogentic viral capsid carrier with cancer targeting activity. Adv. Sci. 1800494.
- 17. Eunji Jo, June Seok Heo, Ja-Yun Lim, Bo-Ram Lee, Chul Joo Yoon, Jinkwan Kim, and Jeewon Lee* (2018) Peptide ligand-mediated endocytosis of nanoparticles to cancer cells: cell receptor-binding- vs. cell membrane-penetrating peptides. Biotechnol. & Bioeng. (DOI 10.1002/bit.26575)
- 18. J.-H. Kwon, H.-T. Kim, S. J. Sim, Y. J. Cha, and J. Lee* (2018) Performance of point-of-care diagnosis of AIDS: Label-free one-step-immunoassay vs. Lateral flow assay. Analyst 143: 936-942. DOI: 10.1039/C7AN01748K
- 19. Seong-Eun Kim, Bo-Ram Lee, Hohyeon Lee, Sung Duk Jo, Hyuncheol Kim, You-Yeon Won, and Jeewon Lee* (2017) Near-Infrared Plasmonic Assemblies of Gold Nanoparticles with Multimodal Function for Targeted Cancer Theragnosis. Scientific Reports 7(1), 17327
- 20. J-H. Kwon, H-T. Kim, J-H. Lee, R. Kim, M. Heo, J. Shin, H-Y. Lee, Y.J. Cha and J. Lee* (2017) Signal self-enhancement by coordinated assembly of gold nano-particles enables accurate one-step-immunoassays. Nanoscale 9: 16476 – 16484. (2)
- 21. Koo Chul Kwon, Eunji Jo, Young-Wan Kwon, Boram Lee, Ju Hee Ryu, Eun Jung Lee, Kwangmeyung Kim, and Jeewon Lee* (2017) Superparamagnetic Gold Nanoparticles Synthesized on Protein Particle Scaffold for Cancer Theragnosis. Advanced Materials 29: 1701146 DOI: 10.1002/adma.201701146 (1)
- 22. Seong-Eun Kim, Sung Duk Jo, Koo Chul Kwon, You-Yeon Won,* and Jeewon Lee* (2017) Genetic Assembly of Double-Layered Fluorescent Protein Nanoparticles for Cancer Targeting and Imaging. Advanced Science 4: 1600471 | DOI: 10.1002/advs.201600471 (1)
- 23. Bo-Ram Lee, Ho Kyung Ko, Ju Hee Ryu, Keum Young Ahn, Young-Ho Lee, Se Jin Oh, Jin Hee Na, Tae Woo Kim, Youngro Byun, Ick Chan Kwon, Kwangmeyung Kim and Jeewon Lee* (2016) Engineered Human Ferritin Nanoparticles for Direct Delivery of Tumor Antigens to Lymph Node and Cancer Immunotherapy. Scientific Reports 6: 35182 | DOI: 10.1038/srep35182. (6)
- 24. Koo Chul Kwon, Ho Kyung Ko, Jiyun Lee, Eun Jung Lee, Kwangmeyung Kim, and Jeewon Lee* (2016) Enhanced in vivo tumor detection by active tumor cell targeting using multiple tumor receptor-binding peptides presented on genetically engineered human ferritin nanoparticles. Small 12(31): 4241–4253 (August 17, 2016) (7)
- 25. Hyun Jin Kim, Eun Jung Lee, Jin-Seung Park, Sang Jun Sim, and Jeewon Lee* (2016) Reversible and multi-cyclic protein-protein interaction in bacterial cellulosome-mimic system using rod-shaped viral nanostructure J. Biotechnol. 221: 101-106. (1)
- 26. Sung Bong Kim, Ja Hyun Lee, Xiaoguang Yang, Jeewon Lee, Seung Wook Kim (2015), Furfural production from hydrolysis of barley straw after dilute sulfuric acid pretreatment. Kor. J. Chem. Eng. 32(11): 2280-2284 (6)
- 27. Hyun Jin Kim, Keum-Young Ahn, Kyung Dong Bae, Jiyun Lee, Sang Jun Sim and Jeewon Lee* (2016) Adjuvant effect of B domain of Staphyloccocal protein A displayed on the surface of hepatitis B virus capsid. Biotechnol. Bioeng. 113(2): 268-274. (3)
- 28. Min-Eui Hong, Sung Kwan Hwang, Won Seok Chang, Byung Woo Kim, Jeewon Lee, and Sang Jun Sim* (2015) Enhanced autotrophic astaxanthin production from Haematococcus pluvialis under high temperature via heat stress-driven Haber–Weiss reaction. Appl. Microbiol. Biotechnol. 99(12): 5203-5215. (24)
- 29. Anh H. Nguyen, Jeewon Lee, Hong Il Choi, Ho Seok Kwak, and Sang Jun Sim* (2015) Fabrication of plasmon length-based surface enhanced Raman scattering for multiplex detection on microfluidic device. Biosens. & Bioelectron. 70: 358-365 (15)
- 30. Min Kyung Kang, Jeewon Lee, Anh H. Nguyen, Sang Jun Sim* (2015) Label-free detection of ApoE4-mediated β-amyloid aggregation on single nanoparticle uncovering Alzheimer's disease. Biosens. & Bioelectron. 72: 197-204. (17)
- 31. Ji Young Yhee, Jangwook Lee, Hyeyoun Chang, Jeewon Lee, Ick Chan Kwon Kwangmeyung Kim* (2015) Molecular imaging and targeted drug delivery using albumin-based nanoparticles. Curr. Pharm. Des. 21(14): 1889-1898. (9)
- 32. Jong-Hwan Lee, Hyuk Seong Seo, Jung-Hyuk Kwon, Hee-Tae Kim, Koo Chul Kwon, Sang Jun Sim, Young Joo Cha, and Jeewon Lee,* (2015) Multiplex Diagnosis of Viral Infectious Diseases (AIDS, Hepatitis C, and Hepatitis A) Based on Point of Care Lateral Flow Assay Using Engineered Proteinticles. Biosens. & Bioelectron. 69: 213-225. (18)
- 33. Eun Jung Lee, So Jin Lee, Yoon-Sik Kang, Ju Hee Ryu, Koo Chul Kwon, Eunji Jo, Ji Young Yhee, Ick Chan Kwon, Kwangmeyung Kim, and Jeewon Lee* (2015) Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells. Adv. Funct. Mater. 25: 1279-1286. (17)
- 34. Yoon-Sik Kang, Jong-AmSong, Kyung-Yeon Han, and Jeewon Lee* (2015) Escherichia coli EDA is a novel fusion expression partner to improve solubility of aggreagation-prone heterologous proteins. J. Biotechnol. 194: 39-47. (8)
- 35. Eun Jung Lee, Euna Lee, Hyun Jin Kim, Jong-Hwan Lee, Keum-Young Ahn, Jin-Seung Park, and Jeewon Lee* (2014) Self-assembled Proteinticle Nanostructures for 3-dimensional Display of Antibodies. Nanoscale 6(24): 14919-14925. (6)
- 36. Jong-Hwan Lee, Ji Yun Lee, Jong-Am Song, Kyung-Yeon Han, Doo Sung Lee, and Jeewon Lee* (2014) A stress-responsive Escherichia coli protein, CysQ is a highly effective solubility enhancer for aggregation-prone heterologous proteins. Protein Expression & Purification 101: 91-98. (September, 2014)
- (DOI: 10.1016/j.pep.2014.06.006) (4)
- 37. Koo Chul Kwon, Ju Hee Ryu, Jong-Hwan Lee, Eun Jung Lee, Ick Chan Kwon, Kwangmeyung Kim, and Jeewon Lee* (2014) Proteinticle/Gold Core/Shell Nanoparticles for Targeted Cancer Therapy without Nanotoxicity. Adv. Mater. 26: 6436-6441.
- (DOI: 10.1002/adma.201401499) (33)
- 38. Keum-Young Ahn, Boram Lee, Kyung-Yeon Han, Jong-Am Song and Jeewon Lee* (2014) Synthesis of Mycoplasma Arginine Deiminase in E. coli Using Stress-responsive Proteins. Enzyme & Microbial Technol. 63: 46-49. (5)
- 39. Keum-Young Ahn, Ho Kyoung Ko, Bo-Ram Lee, Eun Jung Lee, Jong-Hwan Lee, Youngro Byun, Ick Chan Kwon, Kwangmeyung Kim, and Jeewon Lee* (2014) Engineered protein nanoparticles for in vivo tumor detection. Biomaterials 35: 6422-6429. (17)
- 40. Lee, Jong-Hwan; Seo, Hyuk Seong; Song, Jong Am; Kwon, Koo Chul; Lee, Eun Jung; Kim, Ho Jin; Lee, Eun Bong; Cha, Young Joo; Lee, Jeewon* (2013) Proteinticle Engineering for Accurate 3D Diagnosis. ACS Nano 7(12): 10879-10886. (17)
- 41. Dae-Sung Lee, Jin-Seung Park, Eun Jung Lee, Hyun Jin Kim, Jeewon Lee* (2013) Protein nanofiber hydrogel for sensitive immunoassays. Analyst 138(17): 4786-4794. (Back cover) (3)
- 42. Donghyun Park, Jeewon Lee* (2013) Biological conversion of methane to methanol. Kor. J. Chem. Eng. 30(5): 977-987. (37)
- 43. Min Sun Song, Seung Phill Choi, Jeewon Lee, Young Jik Kwon, Sang Jun Sim* (2013) Real-Time, Sensitive, and Specific Detection of Promoter-Polymerase Interactions in Gene Transcription Using a Nanoplasmonic Sensor. Adv. Mater. 25: 1265-1269. (9)
- 44. Lina Yoo, Keum-Young Ahn, Ji-Young Ahn, Thomas Laurell, Yong Man Lee, Pil J. Yoo, and Jeewon Lee* (2013) A simple one-step assay platform based on fluorescence quenching of macroporous silicon. Biosens. & Bioelectron. 41: 477-483. (12)
- 45. Eun Jung Lee, Keum-Young Ahn, Jonghwan Lee, Jin-Seung Park, Jong-AmSong, Sang Jun Sim, Eun Bong Lee, Young Joo Cha, and Jeewon Lee* (2012) A novel bioassay platform using ferritin based nanoprobe hydrogel. Adv. Mater. 24(35): 4739-4744. (Inside front cover) (23)
- 46. Lina Yoo, Jin-Seung Park, Koo Chul Kwon, Seong-Eun Kim, Xiong Jin, Hyunggee Kim, and Jeewon Lee* (2012) Fluorescent viral nanoparticles with stable in vitro and in vivo activity. Biomaterials 33(26): 6194-6200. (17)
- 47. Keum-Young Ahn, Jin-Seung Park, Kyung-Yeon Han, Jong-Am Song, and Jeewon Lee* (2012) YrhB is a highly stable small protein with unique chaperone-like activity in Escherichia coli BL21(DE3). FEBS Letters 586: 1044-1048. (1)
- 48. Jinmi Han, Dohoon Lee, Jinku Cho, Jeewon Lee*, Sangyong Kim* (2012) Hydrogen production from biodiesel byproduct by immobilized Enterobacter aerogenes. Bioprocess. Biosyst. Eng. 35(1): 151-157. (9)
- 49. Jong-Am Song, Dae-Sung Lee, Jin-Seung Park, Kyung-Yeon Han, and Jeewon Lee* (2012) The N-domain of Escherichia coli phosphoglycerate kinase is a novel fusion partner to express aggregation-prone heterologous proteins. Biotechnol. & Bioeng. 109(2): 325-335 (9)
- 50. Keum-Young Ahn, Koo Chul Kwon, Junghwan Huh, Gyu Tae Kim, Eun Bong Lee, Donghyun Park, and Jeewon Lee* (2011) A sensitive diagnostic assay of rheumatoid arthritis using three-dimensional ZnO nanorod structure. Biosensors & Bioelectronics 28: 378-385 (23)
- 51. Seong-Eun Kim, Keum-Young Ahn, Jin-Seung Park, Kyung Rim Kim, Kyung Eun Lee, Sung-Sik Han,and Jeewon Lee* (2011) Fluorescent Ferritin Nanoparticles and Application to Aptamer Sensor. Analytical Chemistry 83(15), 5834-5843 (48)
- 52. Jong-Am Song, Dae-Sung Lee, Jin-Seung Park, Kyung-Yeon Han and Jeewon Lee* (2011) A Novel E. coli Solubility Enhancer Protein for Fusion Expression of Aggregation-prone Heterologous Proteins. Enzyme & Microbial Technol. 49(2), 124-130 (14)
- 53. Kyung Rim Kim, Keum-Young Ahn, Jin-Seung Park, Kyung Eun Lee, Hyesung Jeon and Jeewon Lee* (2011) Lyophilization and Enhanced Stability of Fluorescent Protein Nanoparticles. Biochem. Biophys. Res. Commun. 408(2), 225-229. (8)
- 54. Park DK, Kim HI, Kim JP, Park JS, Lee SY, Yang SM, Lee J, Chung CH, Sim SJ, Yoo PJ* (2010) Rigiflex Lithography-Based Nanodot Arrays for Localized Surface Plasmon Resonance Biosensors. Langmuir 26(9), 6119-6126. (10)
- 55. Hyuk Seong Seo, Seong Eun Kim, Jin-Seung Park, Jong Hwan Lee, Ki-Yeon Yang, Heon Lee, Kyung Eun Lee, Sung-Sik Han, and Jeewon Lee* (2010) A Three-dimensional Nanostructured Array of Protein Nanoparticles. Adv. Funct. Mater. 20(23), 4055-4061. (23)
- 56. Jong-Hwan Lee, Jung Suk Kim,20 Jin-Seung Park, Wonbae Lee, Kyung Eun Lee, Sung-Sik Han, Kyu Back Lee, and Jeewon Lee* (2010) A Three-dimensional and Sensitive Bioassay Based on Nanostructured Quartz Combined with Viral Nanoparticles. Adv. Funct. Mater. 20: 2004-2009. (31)
- 57. Song, Jong-Am; Han, Kyung Yeon; Park, Jin-Seung; Seo, Hyuk-Seong; Ahn, Keum-Young; Lee, Jeewon (2009) Human G-CSF synthesis using stress-responsive bacterial proteins. FEMS Microbiol. Lett. 296: 60-66. (10)
- 58. Song, Jong-Am, Han, Kyung-Yeon, Ahn, Keum-Young, Park, Jin-Seung, Seo, Hyuk-Seong, and Lee, Jeewon* (2009) Proteolysis and Synthetic Strategy of Human G-CSF in Escherichia coli BL21(DE3). Enzyme & Microbial Technol. 45: 7-14. (4)
- 59. Jin-Seung Park, Moon Kyu Cho, Eun Jung Lee, Keum-Young Ahn, Kyung Eun Lee, Jae Hun Jung, Yunjung Cho, Sung-Sik Han, Young Keun Kim, Jeewon Lee* (2009) A highly sensitive and selective diagnostic assay based on virus nanoparticles. Nature Nanotechnol. 4: 259-264. (123)
- 60. Hyuk-Seong Seo, Seong-Eun Kim, Kyung-Yeon Han, Jin-Seung Park, Yong-Hwan Kim and Jeewon Lee* (2009) Functional fusion mutant of Candida antarctica lipase B (CalB) expressed in Escherichia coli. Biochimica et Biophysica Acta – Proteins and Proteomics 1794: 519-525. (18)
- 61. Cuong Cao, Xinxing Li, Jeewon Lee, Sang Jun Sim* (2009) Homogeneous growth of gold nanocrystals for quantification of PSA protein biomarker. Biosensors & Bioelectronics 24: 1292-1297. (40)
- 62. Hyuk-Seong Seo, Jin-Seung Park, Kyung-Yeon Han, Kyung-Dong Bae, Sang Jeom Ahn, Hyun Ah Kang, Jeewon Lee* (2008) Analysis and characterization of hepatitis B vaccine particles synthesized from Hansenula polymorpha. Vaccine 26: 4138-4144 (15)
- 63. Park JS, Han KY, Lee JH, Song JA, Ahn KY, Seo HS, Sim SJ, Kim SW, Lee J* (2008) Solubility enhancement of aggregation-prone heterologous proteins by fusion expression using stress-responsive Escherichia coli protein, RpoS. BMC Biotechnol. 8:15 doi:10.1186/1472-6750-8-15. (22)
- 64. Han KY, Park JS, Seo HS, Ahn KY, Lee J* (2008) Multiple Stressor-induced proteome responses of Escherichia coli BL21(DE3) J. Proteome Res. 7: 1891–1903 (27)
- 65. Chang Duk Kang, Cuong Cao, Jeewon Lee, Insung S. Choi, Byung Woo Kim, Sang Jun Sim*, (2008) Surface plasmon resonance-based inhibition assay for real-time detection of Cryptosporidium parvum oocyst. Water Research 42:1693-1699 (19)
- 66. Han KY, Seo HS, Song JA, Ahn KY, Park JS, Lee J* (2007) Transport Proteins PotD and Crr of Escherichia coli, Novel Fusion Partners for Heterologous Protein Expression. Biochimica et Biophysica Acta – Proteins and Proteomics 1774: 1536-1543 (17)
- 67. Han KY, Song JA, Ahn KY, Park JS, Seo HS, Lee J* (2007) Solubilization of aggregation-prone heterologous proteins by covalent fusion of stress-responsive Escherichia coli protein, SlyD. Protein Engineering Design & Selection 20(11): 543-549. (38)
- 68. Park SW, Park SJ, Han SJ, Lee J, Kim DS, Kim JH, Kim BW, Lee J, Sim SJ (2007) Repeated Batch Production of Epothilone B by Immobilized Sorangium cellulosum J. Microbiol. Biotechnol. 17(7), 1208–1212. (9)
- 69. Keum-Young Ahn, Jong-Am Song, Kyung-Yeon Han, Jin-Seung Park, Hyuk-Seong Seo and Jeewon Lee (2007) Heterologous Protein Expression Using A Novel Stress-Responsive Protein of E. coli RpoA As Fusion Expression Partner. Enzyme and Microbial Technology 41:859-866 (10)
- 70. Lee SH, Lee H, Park JS, Choi H, Han KY, Seo, HS, Ahn KY, Han SS, Cho Y, Lee KH, Lee J* (2007) A Novel approach to ultrasensitive diagnosis using supramolecular protein nanoparticles. The FASEB J. 21(7): 1324-1334. (27)
- 71. Seo HS, Um HJ, Min J, Rhee SK, Cho TJ, Kim YH, Lee J* (2007) Pseudozyma jejuensissp. nov., a novel cutinolytic ustilaginomycetous yeast species that is able to degrade plastic waste. FEMS Yeast Res. (IF 2.477) 7:1035-1045 (35)
- 72. Park JS, Ahn JY, Lee SH, Lee H, Han KY, Seo HS, Ahn KY, Min BH, Sim SJ, Choi IS, Kim YH, Lee J* (2007) Enhanced stability of heterologous proteins by supramolecular self-assembly. Appl. Microbiol. Biotechnol. 75: 347-355 (IF 2.586) (6)
- 73. Han KY, Song JA, Ahn KY, Park JS, Seo HS, Lee J* (2007) Enhanced solubility of heterologous proteins by fusion expression using stress-induced Escherichia coli protein, Tsf. FEMS Microbiol. Lett. 274(1):132-138. (23)
- 74. Jin-Seung Park, Kyung-Yeon Han, Jong-Am Song, Keum-Young Ahn, Hyuk-Seong Seo and Jeewon Lee* (2007) Escherichia coli malate dehydrogenase, a novel solubility enhancer for heterologous proteins synthesized in Escherichia coli. Biotechnol. Lett. 29:1513-1518. (9)
- 75. Lee BS, Lee JK, Kim WJ, Jung YH, Sim SJ, Lee J, Choi IS* (2007) Surface-Initiated, Atom Transfer Radical Polymerization of Oligo(ethylene glycol) Methyl Ether Methacrylate and Subsequent Click Chemistry for Bioconjugation. Biomacromolecules 8: 744-749. (144)
- 76. Kim Y-H, Min J, Han KY, Park JS, Seo HS, Bae KD, Gu MB, Lee J* (2007) Enhanced degradation and toxicity reduction of dihexyl phthalate by Fusarium oxysporum f. sp. pisi cutinase. J. Appl. Microbiol. 102(1): 221-228 (26)
- 77. Ahn JY, Kim YH, Min J, Lee J* (2006) Accelerated degradation of diphenyl phthalate by Fusarium oxysporum f. sp. pisi cutinase and toxicity evaluation of its degradation products uisng bioluminescent bacteria. Curr. Microbiol. 52(5): 340-344. (22)
- 78. Kim YH, Lee J* (2006) Enzymatic degradation and detoxification of diethyl phthalate by Fusarium oxysporum f. sp. pisi cutinase Studies in Surface Science and Catalysis 159: 137-140.
- 79. Kim YH, Kim SW, Lee J* (2006) Characterization of substrate- specificity for cutinase produced by novel Pseudozyma aphidis isolated from pea leaves in South Korea. Studies in Surface Science and Catalysis 159: 125-128.
- 80. Lee DH, Kim JM, Kang SW, Lee J, Kim SW* (2006) Pretreatment of lipase with soybean oil before immobilization to prevent loss of activity. Biotechnol. Lett. 28: 1965-1969. (26)
- 81. Ahn JY, Choi H, Kim YH, Han KY, Park JS, Han SS, Lee J* (2005) Heterologous gene expression using self-assembled supra-molecules with high affinity for HSP70 chaperone. Nucleic Acids Res. 33(12): 3751-3762. (36)
- 82. Park JS, Seo HS, Yum JS, Moon HM, Lee J* (2005) The influence of N-glycosylation and C-terminal sequence on secretion of HBV large surface antigen from S. cerevisiae. Biotechnol. Bioeng. 92(2): 250-255 (4)
- 83. Kim YH, Han KY, Lee KB, Lee J* (2005) Proteome Response of Escherichia coli Fed-batch Culture to Temperature Downshift. Appl. Microbiol. Biotechnol. 68: 786-793. (40)
- 84. Kim YH, Ahn JY, Lee J*, SH Moon (2005) Biodegradation and detoxification of organophosphate insecticide, malathion by Fusarium oxysporum f. sp. pisi cutinase. Chemosphere 60: 1349-1355. (63)
- 85. Kim YH, Min J, Bae KD, Gu MB, Lee J* (2005) Biodegradation of dipropyl phthalate and toxicity of its degradation products: a comparison of Fusarium oxysporum f. sp. pisi cutinase and Candida cylindracea esterase. Archives of Microbiology. 184: 25-31. (22)
- 86. Kim YH, Lee J* (2005) Enzymatic degradation of dibutyl phthalate and toxicity of its degradation products. Biotechnol. Lett. 27(9): 635-639. (14)
- 87. Choi H, Ahn JY, Sim SJ, Lee J* (2005) Glutamate decarboxylase –derived IDDM autoantigens displayed on self-assembled protein nanoparticles. Biochem. Biophys. Res. Commun. 327: 604-608. (6)
- 88. Lee JW, Sim SJ*, Cho SM, Lee J (2005) Characterization of self-assembled monolayer of thiol on gold surface and the fabrication of biosensor chip based on SPR for detection of anti-GAD Ab. Biosensors & Bioelectronics 20(7): 1422-1427. (127)
- 89. Lee PJ, Ahn JY, Kim YH, Kim JY, Park JS, and Lee J* (2004) Cloning and heterologous expression of a novel insecticidal gene (tccC1) from Xenorhabdus nematophilus strain. Biochem. Biophys. Res. Commun. 319: 1110-1116. (25)
- 90. Kim YH, Park JS, Cho JY, Cho KM, Park YH ang Lee J* (2004) Proteomic response analysis of a threonine-overproducing mutant of Escherichia coli. Biochemical J. 381(3): 823-829. (33)
- 91. Kim YH, Han KY, Lee KB, Kang HA, Lee J* (2004) Comparative proteome analysis of Hansenula polymorpha DL1 and A16. Proteomics 4(7): 2005-2013. (14)
- 92. Kim YH, Lee J*, Moon SH (2003) Degradation of an Endocrine Disrupting Chemical, DEHP(Di-(2-Ethylhexyl)-Phthalate) by Fusarium oxysporum f. sp. pisi Cutinase. Appl. Microbiol. Biotechnol. 63: 75-80. (44)
- 93. Park SW, Lee J, Hong SI, Kim SW* (2003) Enhancement of stability of GL-7-ACA acylase immobilized on silica gel modified by epoxide silanization. Process Biochem. 39: 359-366. (14)
- 94. Lee J*, Park JS, Moon JY, Kim KY, Moon HM (2003) The influence of glycosylation on secretion, stability, and immunogenicity of recombinant HBV pre-S antigen synthesized in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 303: 427-432. (48)
- 95. Park SW, Lee J, Hong SI, Kim SW* (2003) Immobilization of glutaryl-7-aminocephalosporanic acid acylase on silica gel and enhancement of its stability. Appl. Biochem. Biotechnol. 104(3): 185-198. (12)
- 96. Kim YH, Lee J*, Moon SH (2003) Uniqueness of microbial cutinase in hydrolysis of p-nitrophenyl esters. J. Microbiol. Biotechnol. 13(1): 57-63. (Times Cited: 0) (24)
- 97. Moon H, Kim SW, Lee J, Rhee SK, Choi ES, Kang HA, Kim IH, Hong SI* (2003) Independent exponential feeding of glycerol and methanol for fed-batch culture of recombinant Hansenula polymorpha DL-1. Appl. Biochem. Biotechnol. 111(2): 65-79 (10)
- 98. Lee J*, Kim SW, Kim YH, Ahn JY (2002) Active human ferritin H/L-hybrid and sequence effect on folding efficiency in Escherichia coli. Biochem. Biophys. Res. Commun. 298: 225-229. (16)
- 99. Kim YH, Lee J*, Ahn JY, Gu MB, Moon SH (2002) Enhanced degradation of an endocrine-disrupting chemical, butyl benzyl phthalate, by Fusarium oxysporum f. sp. pisi cutinase. Appl. Environ. Microbiol. 68(9): 4684-4688. (74)
- 100. Lee J*, Kim HC, Kim SW, Kim SW, Hong SI, Park YH (2002) Interplay of SOS induction, recombinant gene expression, and plasmid multimerization in Escherichia coli. Biotechnol. Bioeng. 80(1): 84-90. (12)
- 101. Kim SW, Kim YH, Lee J* (2001) Thermal stability of human ferritin: concentration dependence and enhanced stability of an N-terminal fusion mutant. Biochem. Biophys. Res. Commun. Nov. 23, 289: 125-129. (16)
- 102. Lee K, Lee J*, Kim YH, Moon SH, Park YH (2001) Unique properties of four Lactobacilli in amino acid production and symbiotic mixed culture for lactic acid biosynthesis. Curr. Microbiol. Nov. 6, 43(6): 383-390. (20)
- 103. Lee J*, Saraswat V, Koh I, Rhee SK, Park YH (2001) Secretory production of Arthrobacter levan fructotransferase from recombinant Escherichia coli. FEMS Microbiol. Lett. Feb. 20, 195(2): 127-132. (22)
- 104. Jeong JC, Lee J*, Park YH (2001) A unique pattern of mycelial elongation of Blakeslea trispora and effect on morphological characteristics and β-carotene synthesis. Curr. Microbiol. Feb. 7, 42(3): 225-228. (15)
- 105. Shin CS, Hong MS, Shin HC, Lee J* (2001) High-level production of recombinant human IFN-α2a with co-expression of tRNAArg(AGG/AGA) in high-cell-density cultures of Escherichia coli. Biotechnol. Bioprocess Eng. 6: 301-305. (6)
- 106. Kim DY, Lee J*, Saraswat V, Park YH (2000) Glucagon-induced self-association of recombinant proteins in Escherichia coli and affinity purification using a fragment of glucagon receptor. Biotechnol. Bioeng. Aug. 20, 69(4): 418-428. (13)
- 107. Saraswat V, Lee J*, Kim DY, Park YH (2000) Synthesis of recombinant human interleukin-2 via controlled feed of lactose- complex media in fed-batch cultures of Escherichia coli BL21(DE3) [pT7-G3IL2]. Biotechnol. Lett. Feb. 4, 22: 261-265. (11)
- 108. Won H-S, Lee J, Kim I-H*, Park Y-H (2000) Simple purification of Escherichia coli-derived recombinant human interleukin-2 expressed with N-terminus fusion glucagon. Biotechnol. Bioprocess Eng. 5: 13-16. (3)
- 109. Saraswat V, Kim DY, Lee J*, Park YH (1999) Effect of specific production rate of recombinant protein on multimerization of plasmid vector and gene expression level. FEMS Microbiol. Lett. Oct. 15, 179(2): 367-373. (21)
- 110. Lee J, Choi SI, Jang JS, Jang KR, Moon JW, Bae CS, Yang DS, Seong BL* (1999) Novel secretion system of recombinant Saccharomyces cerevisiae using an N-terminus residue of human IL-1β as secretion enhancer. Biotechnol. Prog. Aug. 11, 15(5): 884-890. (26)
- 111. Bae CS, Yang DS, Lee J*, and Park YH (1999) Improved process for production of recombinant yeast-derived monomeric human G-CSF. Appl. Microbiol. Biotechnol. Sept. 20, 52(3): 338-344. (24)
- 112. Shin CS, Hong MS, Kim DY, Lee J*, and Park YH (1999) Synthesis of mini-proinsulin precursors using N-termini of human TNFα as fusion partners in recombinant Escherichia coli. J. Ind. Microbiol. Biotechnol. Mar. 7, 22: 176-180. (6)
- 113. Kang MH, Saraswat V, Lee J*, Park Y-H (1999) Production of lyophilized culture of Lactobacillus acidophilus with preserving cell viability. Biotechnol. Bioprocess Eng. 4(1): 36-40. (4)
- 114. Bae CS, Yang DS, Jang KR, Seong BL, and Lee J* (1998) Enhanced secretion of human granulocyte colony-stimulating factor directed by a novel hybrid fusion peptide in recombinant Saccharomyces cerevisiae at high cell concentration. Biotechnol. Bioeng. Mar. 5, 57: 600-609. (38)
- 115. Shin CS, Hong MS, Kim DY, Shin HC, Lee J* (1998) Growth-associated synthesis of recombinant human glucagon and human growth hormone in high cell density cultures of Escherichia coli. Appl. Microbiol. Biotechnol. Apr. 29, 49: 364-370. (63)
- 116. Shin NK, Kim DY, Shin CS, Hong MS, Lee J, Shin HC* (1998) High-level production of human growth hormone in Escherichia coli by a simple recombinant process. J. Biotechnol. Jun. 30, 62: 143-151. (64)
- 117. Kang MH and Lee J* (1998) Continuous cultivation of a human intestinal microflora via controlled culture recycle. Biotechnol. Lett. Mar. 3, 20(3): 295-299. (2)
- 118. Shin CS, Hong MS, Bae CS, and Lee J* (1997) Enhanced production of human mini-proinsulin in fed-batch cultures at high cell density of recombinant Escherichia coli BL21(DE3) [pET-3aT2M2]. Biotechnol. Prog. Mar. 7, 13: 249-257. (122)
- 119. Lee J* (1997) Review: Biological conversion of lignocellulosic biomass to ethanol. J. Biotechnol. July 23, 56(1): 1-24. (812)
- 120. Yang DS, Bae CS, and Lee J* (1997) Production of recombinant human granulocyte colony-stimulating factor in high cell density yeast cultures. Biotechnol. Letts. July 20, 19(7): 655-659. (6)
- 121. Kang MH and Lee J* (1996) An improved procedure for the recovery of pancreatic enzymes with enhanced activity. Biotechnol. Tech. Jun. 4, 10(6): 419-424. (2)
- 122. Shin CS, Hong MS, and Lee J* (1996) Oxygen transfer correlation in high cell density culture of recombinant E. coli. Biotechnol. Tech. Sept. 11, 10(9): 679-682. (13)
- 123. Lee J and Parulekar SJ* (1996) Periodic operation of continuous recombinant cultures improves antibiotic selection. Chem. Eng. Sci. Jan. 10, 51(2): 217-231. (20)
- 124. Lee J*, Soni BK, and Kelley RL (1996) Cell growth and oxygen transfer in Methylosinus trichosporium OB3b cultures. Biotechnol. Letts. Aug. 20, 18(8): 903-908. (6)
- 125. Lee J*, Soni BK, and Kelley RL (1996) Enhancement of biomass production and soluble methane monooxygenase activity in continuous cultures of Methylosinus trichosporium OB3b. Biotechnol. Letts. Aug. 20, 18(8): 897-902. (6)
- 126. Parulekar SJ* and Lee J (1993) Structure analysis of continuous cultures subject to periodic medium tuning. Chem. Eng. Sci. Sept. 5, 48(17): 3007-3035. (10)
- 127. Lee J and Parulekar SJ* (1993) Enhanced production of α-amylase in fed-batch cultures of Bacillus subtilis TN106[pAT5]. Biotechnol. Bioeng. 42: 1142-1150. (40)
- 128. Lee J, Chang H-L, and Parulekar SJ* (1991) An alternate method for estimation of cell growth kinetics from batch culture. Biotechnol. Bioeng. Jan. 5, 37: 26-34. (4)
- Lee J, Lee EK* (2001) Review: Development and applications of Proteomics Technologies. Kor. J. Biotechnol. Bioeng. 16(2): 99-106.
Research
Research Topic
Nanobiotechnology
- -Development of 3D probe with Super-Sensitivity using Self-Assembled Protein Nanoparticles.
- -Application of Protein Nanoparticles to Protein Chip/Sensor and Drug Delivery System.
Microbial Proteomics
- -Novel Biomarker Identification
- -Metabolic Network Analysis
- -Cellular Response Analysis for Expression Proteomics
Biomolecular Process Engineering
- -Development of Heterogenous Gene Expression System using E.coli & Yeast
- -Profusion Peptide Design for In-vivo Protein Folding and Secretion
- -Production of Value-Added Recombinant Proteins
In vivo Imaging
Nano-vaccine
Photothermal therapy of cancer
Synthetic pro-peptide design for protein secretion from Yeast
Lab Members
Ph.D. Candidate
YoungEun Jang

E-mail: youngeunv@korea.ac.kr
Present Address: NEW Engineering Hall 7, 701
Phone: +82-2-3290-3721
Fax: +82-2-953-3722
Education:
1. March 2018 - Present, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (Ph. D course)
2. March 2015 - August 2017, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (master course)
3. March 2012 - February 2014, Department of Chemical and Biological Engineering, Sungkyunkwan University, Seoul, Republic of Korea. (B.S)
4. March 2008 - August 2010, Department of Dental Hygiene, Gachon University, Incheon, Republic of Korea.
YeonHwa Yoo
E-mail: yh.v_v@hanmail.net
Present Address: New Engineering Hall 7, 701
Phone: +82-2-3290-3721
Fax: +82-2-953-3722
Education:
1. March 2017 - Present, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (Ph. D course)
2. March 2013 - February 2017, Department of Chemical Engineering, KyungHee University. (B.S)
HyeHyun Kim

E-mail: gpgus4402@naver.com
Present Address: New Engineering Hall 7, 701
Phone: +82-2-3290-3721
Fax: +82-2-953-3722
Education:
1.March 2017 - Present, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (Ph. D course)
2. March 2012 - February 2017, Department of Biomedical Engineering, Korea University, Seoul, Republic of Korea. (B.S)
YuBin Choi

E-mail: cyb940518@gmail.com
Present Address: New Engineering Hall 7, 701
Phone: +82-2-3290-3721
Fax: +82-2-953-3722
Education:
1. March 2018 - Present, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (Ph. D course)
2. March 2013 - February 2018, Department of Chemical Engineering, Hongik University, Seoul, Republic of Korea. (B.S)
Yong-hwan Seol

E-mail: ilumiee@korea.ac.kr
Present Address: New Engineering Hall 7, 701
Phone: +82-2-3290-3721
Fax: +82-2-953-3722
Education:
1. March 2021 - Present, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (Ph. D course)
2. March 2015 - February 2021, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (B.S)
Master Course
Gyu In Kyung

E-mail: rudrbdls0427@korea.ac.kr
Present Address: NEW Engineering Hall 7, 701
Phone: +82-2-3290-3721
Fax: +82-2-953-3722
Education:
1. September 2023 - Present, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (master course)
2. March 2017 - August 2023, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (B.S)
DaeKwon Park

E-mail: pdkchris@korea.ac.kr
Present Address: New Engineering Hall 7, 701
Phone: +82-2-3290-3721
Fax: +82-2-953-3722
Education:
1. March 2024 - Present, Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea. (master course)
2. March 2020 - February 2024, School of Health and Environmental Science, Korea University, Seoul, Republic of Korea. (B.S)
