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고려대학교 교수소개

Knowledge & Innovation

소개

Prof. 박일호

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E-mail: parkil5@korea.ac.kr

  • About Professor
  • Curriculum Vitae
  • Publication
  • Research
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    안녕하세요. 저는 고려대학교 의과대학 이비인후-두경부외과학 교실의 교수로 재직중인 박일호입니다. 이비인후과라는 전문과목 중에서도 비과(rhinology)를 세부전문과목으로 전공하고 있습니다. 대학에 근무하면서 사회가 요구하는 시스템에 적응하다 보니 의도하든 또는 의도하지 않았든 임상의로서 오랜 기간 세상을 ‘코’라는 작은 창을 통해 바라보았고 그 작은 창으로 보인 세상이 내가 볼 수 있는 가장 멋진 풍경이라고 믿고 지내왔습니다. 문득 어느 날 좁아진 시야에 갇혀 있고 한없이 지루해진 제 자신을 보았습니다. 그리고 다시 오랜 시간 좁아진 창을 다시 넓히고자 끊임없이 노력했고 지금도 노력하고 있습니다. 현재의 제 연구 관심 분야는 크게 3가지로 정리됩니다.

     

    • - Basic research to overcome upper airway chronic inflammatory disease
    • - Development of protocol for medical device usability test and clinical trial
    • - Development of smart healthcare medical devices (Wearables and biosensing personal health tools)

      

       위 연구분야에 대해 연구를 지속하기 위해 2020년 현재 2 가지 다른 분야의 연구팀이 저와 함께 하고 있습니다. 각 연구팀은 4-5명으로 구성되어 있습니다. 각 연구팀은 다음의 명칭을 가지고 있습니다.

    • - ACID (Upper Airway Chronic Inflammatory Disease) Research Laboratory
    • - KU DREAM (Development and Research Acceleration partner for Medical device)

       이름에서 짐작할 수 있겠지만 ACID 팀은 상기도만성염증성질환의 극복을 목적으로 기초연구를 진행하고 있으며 세포, 동물 그리고 임상연구를 동시에 수행합니다. Dream 팀은 의료기기의 Research도 일부 같이 수해하지만 주로 Development를 지원하는 연구를 진행하고 있습니다. 의료기기의 사용환경 조사, 사용자 특성 조사, 관련 규격 안내, 사용적합성 테스트 수행, 임상시험 수행을 하고 있으며 동시에 해당 내용과 관련된 인허가 관련 컨설팅을 수행하고 있습니다.  

     저의 연구관심 분야에 공통점이 있든 없든 소통을 원하시는 모든 연구자와의 소통을 환영합니다. 설명하였듯이 보다 넓은 시야로 세상을 바라보고 싶기 때문입니다.

     

  • Curriculum Vitae

    Education
    교육

    학사 – 고려대학교, 서울

    석사 – 고려대학교, 서울

    박사 – 고려대학교, 서울

    박사후 – Stanford University, Stanford, CA

    연수 – Wake-Forest University, Winton-Salem, NC

    수련

    수련의 – 고려대학교 의료원

    전임의 – 고려대학교 구로병원

     

     

    정부과제수행 지위

    2018-               식약처 고대구로병원 의료기기안전성모니터링센터 센터장

    2018-               보건산업진흥원 고대구로병원 의료기기사용적합성센터 센터장

    2016-               보건산업진흥원 고대구로병원 의료기기중개임상시험센터 부센터장

     

    학회활동

    2006-               대한이비인후과학회 정회원

    2009-               대한비과학회 정회원

    2009-               대한천식알레르기학회 정회원

    2012-               대한안면성형재건학회 정회원

    2019-             대한내시경뇌수술학회 정회원

    2019-               대한수면호흡학회 정회원

     

    학회내 지위

    2015-2017       대한비과학회 학술위원

    2015-2017       대한안면성형재건학회 홍보위원회 간사

    2020-               대한이비인후과학회 법제윤리위원회 간사

    2020-               대한이비인후과학회 국제위원

     

    정부기관 활동

    2018-2020      보건산업진흥원 후원 의료기기 사용적합성 연구회 회장

    2020-               보건산업진흥원 의료기기 시장진출컨설턴트

    2019-               한국보건의료연구원(NECA) 신의료기술평가 전문평가위원

    2019-               건강보험심사평가원(HIRA) 진료심사평가위원회 비상근심사위원

    2019-               식품의약품안전처 의료기기위원회의 전문위원

    2020-               식품의약품안전처 의료기기 기술문서심사기관 심의위원회 심의위원

    2020-               식품의약품안전처 의료제품분야 국가표준(KS) 전문위원

    2018-               한국의료기기안전정보원 의료기기 이상사례 심의위원회 심의위원

    2019-               한국의료기기안전정보원 희소긴급도입필요 의료기기 전문위원회 위원

     

    수상이력

    2010                제13회 한일이비인후과학회 학회장상

    2020                한국의료기기안전정보원 표창장

    (2019 의료기기 안전성정보 모니터링센터 최우수센터 선정)

     

  • Publication

    국제학술지

     

    1. Lee HM, Park IH, Woo JS, Chae SW, Kang HJ, Hwang SJ. Up-regulation of surfactant protein A in chronic sialadenitis. Arch Otolaryngol Head Neck Surg. 2005 Dec;131(12):1108-11.

    2(1). Park IH, Kwon SY, Jung KY, Woo JS. Thyroid hemiagenesis: clinical significance in the patient with thyroid nodule. J Laryngol Otol. 2006 Jul;120(7):605-7.

    3(2). Park IH, Kang HJ, Suh SI, Chae SW. Dural arteriovenous fistula presenting as subjective pulsatile tinnitus. Arch Otolaryngol Head Neck Surg. 2006 Oct;132(10):1148-50.

    4. Park HH, Park IH, Cho JS, Lee YM, Lee HM. The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. Am J Rhinol Allergy. 2010 Sep-Oct;24(5):348-53

    5(3). Park IH, Song JS, Choi H, Kim TH, Hoon S, Lee SH, Lee HM. Volumetric study in the development of paranasal sinuses by CT imaging in Asian: a pilot study. Int J Pediatr Otorhinolaryngol. 2010 Dec;74(12):1347-50.

    6. Lee JH, Chung SW, Park IH, Lee SH, Lee SH, Lee HM. Expression of extracellular matrix metalloproteinase inducer in nasal polyps. Am J Rhinol Allergy. 2010 Nov-Dec;24(6):127-31.

    7(4). Hwang KS, Park IH, Choi H, Lee SH, Lee SH, Lee HM. Increased expression of angiogenin in nasal polyps. Am J Rhinol Allergy. 2011 Jan-Feb;25(1):e23-6.

    8(5). Kim DH, Park IH, Cho JS, Lee YM, Choi H, Lee HM. Alterations of vasoactive intestinal polypeptide receptors in allergic rhinitis. Am J Rhinol Allergy. 2011 Jan-Feb;25(1):e44-7.

    9. Choi H, Park IH, Yoon HG, Lee HM. Wireless patient monitoring system for patients with nasal obstruction. Telemed J E Health. 2011 Jan-Feb;17(1):46-9.

    10. Choi H, Park IH, Yoon HG, Lee HM. Diagnostic accuracy evaluation of nasal sound spectral analysis compared with peak nasal inspiratory flow in nasal septal deviation. Am J Rhinol Allergy. 2011 Mar-Apr;25(2):e86-9.

    11(6). Park IH, Choi SW, Choi H, Kim TH, Lee SH, Lee SH, Lee HM. Increased expression of a disintegrin and metalloprotease 8 in allergic rhinitis. Am J Rhinol Allergy. 2011 May-Jun;25(3):107-11.

    12. Choi H, Cho JS, Park IH, Yoon HG, Lee HM. Effects of microelectrical current on migration of nasal fibroblasts. Am J Rhinol Allergy. 2011 May-Jun;25(3):157-62.

    13. Choi H, Park IH, Yoon HG, Lee HM. Comparison of nasal sound spectral analysis and peak nasal inspiratory flow before and after decongestion in patients with nasal obstruction. Ann Otol Rhinol Laryngol. 2011 Jun;120(6):391-6.

    14(7). Hong SM, Park IH, Kim KM, Shin JM, Lee HM. Relationship between the Korean Version of the Sniffin' Stick Test and the T&T Olfactometer in the Korean Population. Clin Exp Otorhinolaryngol. 2011 Dec;4(4):184-7.

    15(8). Park IH, Park SJ, Cho JS, Moon YM, Moon JH, Kim TH, Lee SH, Lee HM. Effect of simvastatin on transforming growth factor beta-1-induced myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. Am J Rhinol Allergy. 2012 Jan-Feb;26(1):7-11.

    16. Park SA, Park IH, Cho JS, Moon YM, Lee SH, Kim TH, Lee SH, Lee HM. Effect of [6]-gingerol on myofibroblast differentiation in transforming growth factor beta 1-induced nasal polyp-derived fibroblasts. Am J Rhinol Allergy. 2012 Mar-Apr;26(2):97-103.

    17. Lee SH, Choi JH, Park IH, Lee SH, Kim TH, Lee HM, Park HK, Thomas RJ, Shin C, Yun CH. Measuring sleep quality after adenotonsillectomy in pediatric sleep apnea. Laryngoscope. 2012 Apr 11. doi: 10.1002/lary.23356.

    18(9). Park IH, Park SJ, Cho JS, Moon YM, Kim TH, Lee SH, Lee HM. Role of Reactive Oxygen Species in Transforming Growth Factor Beta1-Induced Alpha Smooth-Muscle Actin and Collagen Production in Nasal Polyp-Derived Fibroblasts. Int Arch Allergy Immunol. 2012 Jun 21;159(3):278-286.

    19(10). Park IH, Hong SM, Lee HM. Efficacy and safety of sublingual immunotherapy in Asian children. Int J Pediatr Otorhinolaryngol. 2012 Dec;76(12):1761-6.

    20. Jung J, Lee HC, Park IH, Lee HM. Endoscopic Endonasal Treatment of a Pott's Puffy Tumor. Clin Exp Otorhinolaryngol. 2012 Jun;5(2):112-5.

    21. Cho JS, Moon YM, Um JY, Moon JH, Park IH, Lee HM. Inhibitory effect of ginsenoside Rg1 on extracellular matrix production via extracellular signal-regulated protein kinase/activator protein 1 pathway in nasal polyp-derived fibroblasts. Exp Biol Med (Maywood). 2012 Jun 1;237(6):663-9.

    22. Cho JS, Moon YM, Park IH, Um JY, Moon JH, Park SJ, Lee SH, Kang HJ, Lee HM. Epigenetic regulation of myofibroblast differentiation and extracellular matrix production in nasal polyp-derived fibroblasts. Clin Exp Allergy. 2012 Jun;42(6):872-82

    23(11). Park IH, Park SJ, Cho JS, Moon YM, Kim TH, Lee SH, Lee HM. Increased expression of intelectin-1 in nasal polyps. Am J Rhinol Allergy. 2012 Jul;26(4):274-7.

    24. Moon YM, Kang HJ, Cho JS, Park IH, Lee HM. Nox4 Mediates Hypoxia-Stimulated Myofibroblast Differentiation in Nasal Polyp-Derived Fibroblasts. Int Arch Allergy Immunol. 2012 Jul 26;159(4):399-409.

    25(12). Moon YM, Park IH, Cho JS, Um JY, Kim TH, Lee HM. Berberine inhibits myofibroblast differentiation in nasal polyp-derived fibroblasts via the p38 pathway. Phytother Res. 2013 Jan;27(1):16-20.

    26. Cho JS, Moon YM, Park IH, Um JY, Kang JH, Kim TH, Lee SH, Kang HJ, Lee HM. Effects of histone deacetylase inhibitor on extracellular matrix production in human nasal polyp organ cultures. Am J Rhinol Allergy. 2013 Jan;27(1):18-23.

    27(13). Jung JW, Park IH, Cho JS, Lee HM. Naringenin inhibits extracellular matrix production via extracellular signal-regulated kinase pathways in nasal polyp-derived fibroblasts. Phytother Res. 2013 Mar;27(3):463-7.

    28(14). Park IH, Lee HC, Lee HM. Respiratory epithelial adenomatoid hamartoma originating from nasal septum. Clin Exp Otorhinolaryngol. 2013 Mar;6(1):45-7.

    29. Lee HM, Park MS, Park IH, Lee SH, Lee SK, Kim KS, Choi H. A comparative pilot study of symptom improvement before and after phototherapy in Korean patients with perennial allergic rhinitis. Photochem Photobiol. 2013 May-Jun;89(3):751-7.

    30(15). Park IH, Hong SM, Choi H, Chang H, Lee HM. Sclerosing polycystic adenosis of the nasal septum: the risk of misdiagnosis. Clin Exp Otorhinolaryngol. 2013 Jun;6(2):107-9.

    31. Hong SM, Cho JS, Um JY, Shin JM, Park IH, Lee SH, Lee SH, Lee HM. Increased expression of high-mobility group protein B1 in chronic rhinosinusitis. Am J Rhinol Allergy. 2013 Jul-Aug;27(4):278-82.

    32. Wine JJ, Char JE, Chen J, Cho HJ, Dunn C, Frisbee E, Joo NS, Milla C, Modlin SE, Park IH, Thomas EA, Tran KV, Verma R, Wolfe MH. In vivo readout of CFTR function: ratiometric measurement of CFTR-dependent secretion by individual, identifiable human sweat glands. PLoS One. 2013;8(10):e77114.

    33(16). Kang JS, Park IH, Cho JS, Hong SM, Kim TH, Lee SH, Lee HM. Epigallocatechin-3-gallate inhibits collagen production of nasal polyp-derived fibroblasts. Phytother Res. 2014 Jan;28(1):98-103.

    34(17). Park IH, Um JY, Hong SM, Cho JS, Lee SH, Lee SH, Lee HM. Metformin Reduces TGF-β1-Induced Extracellular Matrix Production in Nasal Polyp-Derived Fibroblasts. Otolaryngol Head Neck Surg. 2014 Jan;150(1):148-53.

    35(18). Shin JM, Park IH, Moon YM, Hong SM, Cho JS, Um JY, Lee HM. IInhibitory effect of prostaglandin E2 on the migration of nasal fibroblasts. Am J Rhinol Allergy. 2014 May;28(3):120-4.

    36. Char JE, Wolfe MH, Cho HJ, Park IH, Jeong JH, Frisbee E, Dunn C, Davies Z, Milla C, Moss RB, Thomas EA, Wine JJ. A little CFTR goes a long way: CFTR-dependent sweat secretion from G551D and R117H-5T cystic fibrosis subjects taking ivacaftor. PLoS One. 2014 Feb 10;9(2):e88564.

    37. Cho JS, Kang JH, Park IH, Lee HM. Steroids inhibit vascular endothelial growth factor expression via TLR4/Akt/NF-κB pathway in chronic rhinosinusitis with nasal polyp. Exp Biol Med (Maywood). 2014 Jun 13;239(8):913-921.

    38. Cho JH, Suh JD, Kim JK, Hong SC, Park IH, Lee HM. Correlation between skin-prick testing, individual specific IgE tests, and a multiallergen IgE assay for allergy detection in patients with chronic rhinitis. Am J Rhinol Allergy. 2014 Sep-Oct;28(5):388-91.

    39(19). Park IH, Um JY, Cho JS, Lee SH, Lee SH, Lee HM. Histamine Promotes the Release of Interleukin-6 via the H1R/p38 and NF-κB Pathways in Nasal Fibroblasts. Allergy Asthma Immunol Res. 2014 Nov;6(6):567-72.

    40. Cho JS, Kang JH, Um JY, Han IH, Park IH, Lee HM. Lipopolysaccharide Induces Pro-Inflammatory Cytokines and MMP Production via TLR4 in Nasal Polyp-Derived Fibroblast and Organ Culture. PLoS One. 2014 Nov 12;9(11):e90683

    41. Chung SW, Park IH, Hong SM, Cho JS, Moon JH, Kim TH, Lee HM. Role of caffeic Acid on collagen production in nasal polyp-derived fibroblasts. Clin Exp Otorhinolaryngol. 2014 Dec;7(4):295-301.

    42(20). Hwang SJ, Ok S, Lee HM, Lee E, Park IH. Human papillomavirus-related carcinoma with adenoid cystic-like features of the inferior turbinate: A case report. Auris Nasus Larynx. 2015 Feb;42(1)

    43. Cho JS, Park JH, Kang JH, Kim SE, Park IH, Lee HM. Isolation and characterization of multipotent mesenchymal stem cells in nasal polyps. Exp Biol Med (Maywood). 2015 Feb;240(2):185-93.

    44. Joo NS, Evans IA, Cho HJ, Park IH, Engelhardt JF, Wine JJ. Proteomic analysis of pure human airway gland mucus reveals a large component of protective proteins. PLoS One. 2015 Feb 23;10(2):e0116756

    45. Cho JS, Kang JH, Shin JM, Park IH, Lee HM. Inhibitory Effect of Delphinidin on Extracellular Matrix Production via the MAPK/NF-κB Pathway in Nasal Polyp-Derived Fibroblasts. Allergy Asthma Immunol Res. 2015 May;7(3):276-82.

    46. Choi JH, Thomas RJ, Suh SY, Park IH, Kim TH, Lee SH, Lee HM, Yun CH, Lee SH. Sleep quality change after upper airway surgery in obstructive sleep apnea: Electrocardiogram-based cardiopulmonary coupling analysis. Laryngoscope. 2015 Jul;125(7):1737-42.

    47. Choi JH, Oh JI, Kim TM, Yoon HC, Park IH, Kim TH, Lee HM, Lee SH, Lee SH. Long-term Subjective and Objective Outcomes of Adenotonsillectomy in Korean Children With Obstructive Sleep Apnea Syndrome. Clin Exp Otorhinolaryngol. 2015 Sep;8(3):256-60.

    48. Choi JH, Yoon HC, Kim TM, Choi J, Park IH, Kim TH, Lee HM, Lee SH, Lee SH. The immediate effect of adenotonsillectomy on Eustachian tube function in children. Int J Pediatr Otorhinolaryngol. 2015 Sep;79(9):1444-7.

    49. Cho JS, Kang JH, Han IH, Um JY, Park IH, Lee SH, Lee HM. Antiallergic Effects of Trichostatin A in a Murine Model of Allergic Rhinitis. Clin Exp Otorhinolaryngol. 2015 Sep;8(3):243-9.

    50(21). Hong SM, Park IH, Um JY, Shin JM, Lee HM. Stimulatory effects of histamine on migration of nasal fibroblasts. Int Forum Allergy Rhinol. 2015 Oct;5(10):923-8.

    51. Shin JM, Park JH, Park IH, Lee HM. Pirfenidone inhibits transforming growth factor β1-induced extracellular matrix production in nasal polyp-derived fibroblasts. Am J Rhinol Allergy. 2015 Nov;29(6):408-13.

    52(22). Park IH, Lee HM, Yanagi K. Endoscopic transantral and transnasal repair of orbital floor fracture with the ballooning technique, and classification and characterization of orbital floor fractures. Am J Rhinol Allergy. 2015 Nov;29(6):445-8.

    53. Shin JM, Park JH, Park IH, Lee HM. Doxycycline inhibits TGF-β1-induced extracellular matrix production in nasal polyp-derived fibroblasts. Int Forum Allergy Rhinol. 2016 Mar;6(3):256-63.

    54. Kim JA, Cho JH, Park IH, Shin JM, Lee SA, Lee HM. Diesel Exhaust Particles Upregulate Interleukins IL-6 and IL-8 in Nasal Fibroblasts. PLoS One. 2016 Jun 13;11(6):e0157058.

    55. Ryu NH, Shin JM, Um JY, Park IH, Lee HM. Wogonin inhibits transforming growth factor β1-induced extracellular matrix production via the p38/activator protein 1 signaling pathway in nasal polyp-derived fibroblasts. Am J Rhinol Allergy. 2016 Jul;30(4):128-33.

    55(23). Park IH, Kang JH, Shin JM, Lee HM. Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium. PLoS One. 2016 Aug 29;11(8):e0162058.

    56(24). Park IH, Park JH, Shin JM, Lee HM. Tumor necrosis factor-α regulates interleukin-33 expression through extracellular signal-regulated kinase, p38, and nuclear factor-κB pathways in airway epithelial cells. Int Forum Allergy Rhinol. 2016 Sep;6(9):973-80.

    58. Cho JS, Kim JA, Park JH, Park IH, Han IH, Lee HM. Toll-like receptor 4-mediated expression of interleukin-32 via the c-Jun N-terminal kinase/protein kinase B/cyclic adenosine monophosphate response element binding protein pathway in chronic rhinosinusitis with nasal polyps. Int Forum Allergy Rhinol. 2016 Oct;6(10):1020-1028.

    59(25). Park IH, Kang JH, Kim JA, Shin JM, Lee HM. Diesel Exhaust Particles Enhance MUC4 Expression in NCI-H292 Cells and Nasal Epithelial Cells via the p38/CREB Pathway. Int Arch Allergy Immunol. 2016;171(3-4):209-216.

    60. Kang B, Kim JR, Shin JM, Park IH, Lee HM. Efficacy and Safety of Guardcel Nasal Packing After Endoscopic Sinus Surgery: A Prospective, Single-Blind, Randomized Controlled Study. Clin Exp Otorhinolaryngol. 2017 Sep;10(3):248-253.

    61. Shin JM, Kang JH, Lee SA, Park IH, Lee HM. Baicalin Down-Regulates IL-1β-Stimulated Extracellular Matrix Production in Nasal Fibroblasts. PLoS One. 2016 Dec 21;11(12):e0168195.

    62. Shin JM, Park JH, Kang B, Lee SA, Park IH, Lee HM. Effect of doxycycline on transforming growth factor-beta-1-induced matrix metalloproteinase 2 expression, migration, and collagen contraction in nasal polyp-derived fibroblasts. Am J Rhinol Allergy. 2016 Nov 1;30(6):385-390.

    63. Ko DY, Shin JM, Um JY, Kang B, Park IH, Lee HM. Rapamycin inhibits transforming growth factor beta 1 induced myofibroblast differentiation via the phosphorylated-phosphatidylinositol 3-kinase mammalian target of rapamycin signal pathways in nasal polyp-derived fibroblasts. Am J Rhinol Allergy. 2016 Nov 1;30(6):211-217.

    64. Shin JM, Park JH, Kim HJ, Park IH, Lee HM. Cigarette smoke extract increases vascular endothelial growth factor production via TLR4/ROS/MAPKs/NF-kappaB pathway in nasal fibroblast. Am J Rhinol Allergy. 2017 Mar 1;31(2):78-84.

    65. Shin JM, Kang JH, Lee SA, Park IH, Lee HM. Effect of doxycycline on epithelial-mesenchymal transition via the p38/Smad pathway in respiratory epithelial cells. Am J Rhinol Allergy. 2017 Mar 1;31(2):71-77.

    66. Yang HW, Lee SA, Shin JM, Park IH, Lee HM. Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways. Sci Rep. 2017 Jun 14;7(1):3486.

    67. Lee SA, Yang HW, Um JY, Shin JM, Park IH, Lee HM. Vitamin D attenuates myofibroblast differentiation and extracellular matrix accumulation in nasal polyp-derived fibroblasts through smad2/3 signaling pathway. Sci Rep. 2017 Aug 4;7(1):7299.

    68. Kim SJ, Shin JM, Lee EJ, Park IH, Lee HM, Kim KS. Efficacy of hyaluronic acid and hydroxyethyl starch in preventing adhesion following endoscopic sinus surgery. Eur Arch Otorhinolaryngol. 2017 Oct;274(10):3643-3649.

    69(26). Lee HM, Kang JH, Shin JM, Lee SA, Park IH. Chemical Chaperone of Endoplasmic Reticulum Stress Inhibits Epithelial-Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium via the c-Src Pathway. Mediators Inflamm. 2017;2017:8123281.

    70. Um JY, Lee SA, Park JH, Shin JM, Park IH, Lee HM. Role of adenosine monophosphate-activated protein kinase on cell migration, matrix contraction, and matrix metalloproteinase-1 and matrix metalloproteinase-2 production in nasal polyp-derived fibroblasts. Am J Rhinol Allergy. 2017 Nov 1;31(6):357-363.

    71. Kim B, Lee HJ, Im NR, Lee DY, Kang CY, Park IH, Lee SH, Lee SH, Baek SK, Kim TH. Effect of matrix metalloproteinase inhibitor on disrupted E-cadherin after acid exposure in the human nasal epithelium. Laryngoscope. 2018 Jan;128(1):E1-E7.

    72. Kim B, Lee HJ, Im NR, Lee DY, Kim HK, Kang CY, Park IH, Lee SH, Lee HM, Lee SH, Baek SK, Kim TH. Decreased expression of CCL17 in the disrupted nasal polyp epithelium and its regulation by IL-4 and IL-5. PLoS One. 2018 May 10;13(5):e0197355.

    73. Shin JM, Um JY, Lee SA, Park IH, Lee SH, Lee HM. Effect of MeCP2 on TGF- β1-induced Extracellular Matrix Production in Nasal Polyp-derived Fibroblasts. Am J Rhinol Allergy. 2018 Jul;32(4):228-235.

    74. Kim CH, Ryu SY, Yoon JY, Lee HK, Choi NG, Park IH, Choi HY. See-Through Type 3D Head-Mounted Display-Based Surgical Microscope System for Microsurgery: A Feasibility Study. JMIR Mhealth Uhealth. 2019 Mar 7;7(3):e11251.

    75(27). Kim HJ, Park JH, Shin JM, Yang HW, Lee HM, Park IH. TGF-β1-induced HSP47 regulates extracellular matrix accumulation via Smad2/3 signaling pathways in nasal fibroblasts. Sci Rep. 2019 Oct 29;9(1):15563.

    76(28). Yang HW, Park JH, Shin JM, Lee HM, Park IH. Asian Sand Dust Upregulates IL-6 and IL-8 via ROS, JNK, ERK, and CREB Signaling in Human Nasal Fibroblasts. Am J Rhinol Allergy. 2020 Mar;34(2):249-261.

    77(29). Shin JM, Park JH, Yang HW, Lee HM, Park IH. Cigarette smoke extract inhibits cell migration and contraction via the reactive oxygen species/adenosine monophosphate-activated protein kinase pathway in nasal fibroblasts. Int Forum Allergy Rhinol. 2020 Mar;10(3):356-363.

    78. Khan MA, Kwon S, Choo J, Hong SM, Kang SH, Park IH, Kim SK, Hong SJ. Automatic detection of tympanic membrane and middle ear infection from oto-endoscopic images via convolutional neural networks. Neural Netw. 2020 Jun;126:384-394.

    79(30) Kang JH, Yang HW, Park JH, Shin JM, Kim TH, Lee SH, Lee HM, Park IH. Lipopolysaccharide regulates thymic stromal lymphopoietin expression via TLR4/MAPK/Akt/NF-κB-signaling pathways in nasal fibroblasts: differential inhibitory effects of macrolide and corticosteroid. Int Forum Allergy Rhinol. 2020 Jul 5. [Epub ahead of print]

     

     

     

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