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소개

Prof. 동은상

Tel:  02-2626-1190

E-mail: prsdhong@kumc.or.kr

  • About Professor
  • Curriculum Vitae
  • Publication
  • Research
  • Lab Members

  • Profile

    전공 : 코성형, 미세수술


    자가 조직을 이용한 코 수술

    실리콘 등을 이용한 보형물 (alloplastic implant)은 합병증만 없다면 반 영구적이다.

    반 영구적이지만 스스로의 한계 (수명 : longevity) 가 분명 존재한다.

    이에 반해서 자가조직은 5-10일의 경과 기간이 지나서 생착이 되면 오히려 영구적이라고 볼 수 있다.

    그러나 자가조직은 흡수라는 문제에서 자유스럽지 못하다.

    혈류가 도달하지 않은 자가 조직은 결국 몸에서 자기의 조직으로 받아들이지 않는다. 일부 흉이되어 영구적으로 남고 일부는 흉이 되지 못하고 아주 천천히 흡수된다.

    그 흡수율은 작게는 30%에서 크게는 80%까지 상황에 따라 예측이 불가능 할 정도로 다양한 비율을 보인다. 그러면 누가 자가 조직으로 코 수술을 할 것이며 어떻게 환자에게 권할 것인가?

    그러나 원래 자기 위치에 있어야 할 조직 , 예를 들면 비중격 연골 부위에 이식한 귀연골, 콧등에 얇게 이식한 한 두겹의 진피 등은 흡수율이 현저히 낮고 유지가 잘 되는 것을 볼 수있다. 즉 과도하지 않게 자기 위치에 있어야 할 부위에 이식한 자가 조직은 마치 원래 그 자리에 있었던 조직처럼 자연 스럽게 자기 일을 하는 것이다.

    생체에 적용되는 모든 조직 이식이 그러하다.

    몸은 원래 있어야 할 부위의 연 조직을 한계 범위 내에서만 허용하는 듯 하다.

    의학 전반에서 기본적인 생리현상인 항상성(homeostasis)을 유지하려는 몸의 방어기능이라 볼 수 있다.


    모든 환자는 다른 상황을 가지고 있으며 이런 견지에서 모든 환자는 다른 결과를 보일 수 있다고 말 할 수 있다.

    따라서 모든 환자는 각각의 상황에서 의사를 가르치는 스승이다. 이렇게 다른 상황을 많이 격어본 의사는 경험을 통해 나름의 결과를 예측하고 그런 경험을 토대로 자가조직을 이식하게 되는 것이다.

     

  • Curriculum Vitae

    Eun-Sang Dhong MD PhD: 동 은상 교수



  • Publication

    • 1. Namgoong S, Yoon YD, Yoo KH, Han SK, Kim WK, Dhong ES. Alternative Choices for Anterolateral Thigh Flaps Lacking Suitable Perforators: A Systematic Review. J Reconstr Microsurg. 2018.
    • 2. Hwang NH, Dhong ES. Septal Extension Graft in Asian Rhinoplasty. Facial Plast Surg Clin North Am. 2018;26(3):331-341.
    • 3. Moon KC, Lee JS, Han SK, Lee HW, Dhong ES. Effects of human umbilical cord blood-derived mesenchymal stromal cells and dermal fibroblasts on diabetic wound healing. Cytotherapy. 2017;19(7):821-828.
    • 4. Lee SC, Park SH, Han SK, et al. Prognostic Factors of Orbital Fractures with Muscle Incarceration. Arch Plast Surg. 2017;44(5):407-412.
    • 5. Lee JS, Tae SS, Kim DY, Han SK, Kim WK, Dhong ES. Do IL-3/GM-CSF effect on the myofibroblastic differentiation of human adipose derived stromal cells? Exp Cell Res. 2017;355(2):67-82.
    • 6. Jung JA, Han SK, Jeong SH, Dhong ES, Park KG, Kim WK. In Vitro Evaluation of Betafoam, a New Polyurethane Foam Dressing. Adv Skin Wound Care. 2017;30(6):262-271.
    • 7. Jung JA, Dhong ES, Han SK. Reply: Nostrilplasty by Manipulating the Dilator Naris Muscles: A Pilot Study. Plast Reconstr Surg. 2017;139(5):1210e-1211e.
    • 8. You HJ, Yun TK, Jeong SH, Dhong ES, Han SK. Salivary Duct Carcinoma of the Deep Lobe of the Parotid Gland: A Rare Clinical Finding. Arch Plast Surg. 2016;43(1):107-110.
    • 9. Shim JH, Hwang NH, Yoon ES, Dhong ES, Kim DW, Kim SD. Closure of Myelomeningocele Defects Using a Limberg Flap or Direct Repair. Arch Plast Surg. 2016;43(1):26-31.
    • 10. Park KG, Dhong ES, Goong SN, Han JK, Han SK, Kim WK. Recurrent Extranodal NK/T-Cell Lymphoma Presenting as a Perforating Palatal Ulcer and Oro-Nasal Fistula. Arch Craniofac Surg. 2016;17(3):165-168.
    • 11. Park KG, Dhong ES, Goong SN, Han JK, Han SK, Kim WK. Atypical Facial Filler Granuloma: Comparative Histologic Analysis with Paraffinoma. Arch Craniofac Surg. 2016;17(3):169-172.
    • 12. Namgoong S, Jung S, Han SK, Jeong SH, Dhong ES, Kim WK. Risk factors for major amputation in hospitalised diabetic foot patients. Int Wound J. 2016;13 Suppl 1:13-19.
    • 13. Lee GY, Park KG, Namgoong S, et al. Effects of Panax ginseng extract on human dermal fibroblast proliferation and collagen synthesis. Int Wound J. 2016;13 Suppl 1:42-46.
    • 14. Kim DY, Kim DW, Dhong ES. Reply: Treatment of hydrofluoric acid burns of the fingers. J Plast Reconstr Aesthet Surg. 2016;69(4):582-583.
    • 15. Jung JA, Yoo KH, Han SK, et al. Influence of Negative-Pressure Wound Therapy on Tissue Oxygenation in Diabetic Feet. Adv Skin Wound Care. 2016;29(8):364-370.
    • 16. Jung JA, Yoo KH, Han SK, Dhong ES, Kim WK. Evaluation of the Efficacy of Highly Hydrophilic Polyurethane Foam Dressing in Treating a Diabetic Foot Ulcer. Adv Skin Wound Care. 2016;29(12):546-555.
    • 17. Jung JA, Jung SY, Han SK, Dhong ES, Kim WK. Nostrilplasty by Manipulating the Dilator Naris Muscles: A Pilot Study. Plast Reconstr Surg. 2016;138(5):1010-1013.
    • 18. Jeon BJ, Kim DW, Kim MS, et al. Protective effects of adipose-derived stem cells against UVB-induced skin pigmentation. J Plast Surg Hand Surg. 2016;50(6):336-342.
    • 19. You HJ, Namgoong S, Han SK, Jeong SH, Dhong ES, Kim WK. Wound-healing potential of human umbilical cord blood-derived mesenchymal stromal cells in vitro--a pilot study. Cytotherapy. 2015;17(11):1506-1513.
    • 20. Shin SH, Yun TK, Han SK, Jeong SH, Dhong ES, Kim WK. Comparison of the Matrix Synthesizing Abilities of Human Adipose-Derived Stromal Vascular Fraction Cells and Fibroblasts. J Craniofac Surg. 2015;26(4):1246-1250.
    • 21. Kim DY, Namgoong S, Han SK, et al. Optimal Viscosity and Particle Shape of Hyaluronic Acid Filler as a Scaffold for Human Fibroblasts. J Craniofac Surg. 2015;26(5):1534-1538.
    • 22. Kim DY, Kim DW, Dhong ES. Early surgical treatment by free flap reconstruction of hydrofluoric acid burn injury. J Plast Reconstr Aesthet Surg. 2015;68(10):1477-1478.
    • 23. Kim DW, Hwang NH, Yoon ES, Dhong ES, Park SH. Outcomes of ablative fractional laser scar treatment. J Plast Surg Hand Surg. 2015;49(2):88-94.
    • 24. You HJ, Kim DW, Dhong ES, Yoon ES. Precaruncular approach for the reconstruction of medial orbital wall fractures. Ann Plast Surg. 2014;72(6):652-656.
    • 25. Shon YS, Lee YN, Jeong SH, Dhong ES, Han SK. Influence of negative-pressure wound therapy on tissue oxygenation of the foot. Arch Plast Surg. 2014;41(6):668-672.
    • 26. Park HJ, Gu JH, Jang JC, Dhong ES, Yoon ES. Correction of pectus excavatum with breast hypoplasia using simultaneous pectus bar procedure and augmentation mammoplasty. Ann Plast Surg. 2014;73(2):190-195.
    • 27. Moon KC, Han SK, Lee YN, Jeong SH, Dhong ES, Kim WK. Effect of normobaric hyperoxic therapy on tissue oxygenation in diabetic feet: a pilot study. J Plast Reconstr Aesthet Surg. 2014;67(11):1580-1586.
    • 28. Kim DY, Ji YH, Kim DW, Dhong ES, Yoon ES. Effects of platelet-rich plasma, adipose-derived stem cells, and stromal vascular fraction on the survival of human transplanted adipose tissue. J Korean Med Sci. 2014;29 Suppl 3:S193-200.
    • 29. Kim DW, Jeon BJ, Hwang NH, et al. Adipose-derived stem cells inhibit epidermal melanocytes through an interleukin-6-mediated mechanism. Plast Reconstr Surg. 2014;134(3):470-480.
    • 30. Jeon H, Jeong SH, Dhong ES, Han SK. Pilomatricoma arising at an influenza vaccination site. Arch Plast Surg. 2014;41(6):775-777.
    • 31. Chung JH, Jeong SH, Dhong ES, Han SK. Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique. Arch Plast Surg. 2014;41(3):296-299.
    • 32. Choi JI, Dhong ES, Lim DJ, Kim SD. Reduction cranioplasty for macrocephaly with long-standing hydrocephalus and non-fused fontanelle in Chiari malformation type I. Childs Nerv Syst. 2014;30(10):1763-1766.
    • 33. You JP, Kim DW, Jeon BJ, et al. Two-Year Follow-up on the Use of Absorbable Mesh Plates in the Treatment of Medial Orbital Wall Fractures. Arch Plast Surg. 2013;40(6):728-734.
    • 34. Suh MK, Ahn ES, Kim HR, Dhong ES. A 2-year follow-up of irradiated homologous costal cartilage used as a septal extension graft for the correction of contracted nose in Asians. Ann Plast Surg. 2013;71(1):45-49.
    • 35. Lee DS, Jung SI, Kim DW, Dhong ES. Anterograde intra-arterial urokinase injection for salvaging fibular free flap. Arch Plast Surg. 2013;40(3):251-255.

  • Research

    Research Topic

    1. Neurocosmetics by nerve protection

    • - Verify the mechanism behind GM-CSF and neuroaging
    • - UV damaged skin and GM-CSF
    • - Antagonizing the GM-CSF pathway: inhibition of neurodegeneration?

    2. Capsular contracture biology on MFB differentiation

    • - Do inflammatory cytokines affect MFB phenotypic differentiation in hASCs and HDF?
    • - The biology of CD47 inhibition and MFB differentiation

     Research Fields 1 Life Science and Biotechnology·Health and Medical 2 Basic Research

    Keywords Contracture, Myofibroblast, CD47, Thrombospondin, Activin A, Neuroaging, Neurocosmetics

     

     

  • Lab Members

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